Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHKA
  • Mouse genes Chka
  • Rat genes Chka
  • Zfish genes chka
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chka

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Chka	IDA		Rat	PMID:12815193|RGD:1626304
Molecular Function	GO:0033265	choline binding	Chka	IDA		Rat	PMID:12815193|RGD:1626304
Molecular Function	GO:0004103	choline kinase activity	CHKA	IDA		Human	PMID:19915674
Molecular Function	GO:0004103	choline kinase activity	CHKA	IDA		Human	PMID:34077757
Molecular Function	GO:0004103	choline kinase activity	Chka	IDA		Mouse	PMID:16861741
Molecular Function	GO:0004103	choline kinase activity	Chka	IDA		Mouse	PMID:11964179
Molecular Function	GO:0004103	choline kinase activity	Chka	IDA		Rat	PMID:12815193|RGD:1626304
Molecular Function	GO:0004103	choline kinase activity	Chka	IDA		Rat	PMID:1577786|RGD:61551
Molecular Function	GO:0004104	cholinesterase activity	Chka	IDA		Mouse	PMID:16371353
Molecular Function	GO:0004305	ethanolamine kinase activity	CHKA	IDA		Human	PMID:19915674
Molecular Function	GO:0004305	ethanolamine kinase activity	Chka	IDA		Rat	PMID:1577786|RGD:61551
Molecular Function	GO:0042802	identical protein binding	Chka	IPI	PR:O54804	Mouse	PMID:16371353
Molecular Function	GO:0042803	protein homodimerization activity	CHKA	IDA		Human	PMID:34077757
Cellular Component	GO:0005829	cytosol	CHKA	IDA		Human	PMID:34077757
Biological Process	GO:0019695	choline metabolic process	Chka	IDA		Rat	PMID:12815193|RGD:1626304
Biological Process	GO:0006580	ethanolamine metabolic process	Chka	IDA		Rat	PMID:1577786|RGD:61551
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	CHKA	IDA		Human	PMID:19915674
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	CHKA	IDA		Human	PMID:34077757
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	Chka	IDA		Mouse	PMID:16371353
Biological Process	GO:0006646	phosphatidylethanolamine biosynthetic process	CHKA	IDA		Human	PMID:19915674
Biological Process	GO:1904681	response to 3-methylcholanthrene	Chka	IEP		Rat	PMID:7852267|RGD:632361
Biological Process	GO:0009636	response to toxic substance	Chka	IEP		Rat	PMID:7852267|RGD:632361

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern