Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHL1
  • Mouse genes Chl1
  • Rat genes Chl1
  • Zfish genes chl1a,chl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002020	protease binding	Chl1	IPI	UniProtKB:Q05910	Mouse	MGI:MGI:3040545|PMID:14761956
Molecular Function	GO:0005515	protein binding	Chl1	IPI	UniProtKB:P18052|UniProtKB:Q9JMB8	Mouse	MGI:MGI:3771533|PMID:18046458
Cellular Component	GO:0045177	apical part of cell	Chl1	IDA		Mouse	PMID:15504324
Cellular Component	GO:0030425	dendrite	Chl1	IDA		Mouse	PMID:15504324
Cellular Component	GO:0070062	extracellular exosome	CHL1	HDA		Human	PMID:23533145
Biological Process	GO:0008344	adult locomotory behavior	Chl1	IMP	MGI:MGI:2429688	Mouse	PMID:14659567
Biological Process	GO:0007411	axon guidance	Chl1	IMP	MGI:MGI:2429688	Mouse	PMID:12391163
Biological Process	GO:0031103	axon regeneration	Chl1	IEP		Rat	PMID:14707551|RGD:1303346
Biological Process	GO:0050890	cognition	Chl1	IMP	MGI:MGI:2429688	Mouse	PMID:14659567
Biological Process	GO:0035640	exploration behavior	Chl1	IMP	MGI:MGI:2429688	Mouse	PMID:12391163
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Chl1	IDA		Mouse	MGI:MGI:3040545|PMID:14761956
Biological Process	GO:0001764	neuron migration	Chl1	IMP	MGI:MGI:2429688	Mouse	PMID:15504324
Biological Process	GO:0031175	neuron projection development	Chl1	IDA		Mouse	PMID:10103075
Biological Process	GO:0021591	ventricular system development	chl1a	IMP	ZFIN:ZDB-MRPHLNO-211026-3	Zfish	PMID:32902807
Biological Process	GO:0021591	ventricular system development	chl1a	IMP	ZFIN:ZDB-MRPHLNO-220329-2	Zfish	PMID:32902807
Biological Process	GO:0021591	ventricular system development	chl1a	IMP	ZFIN:ZDB-MRPHLNO-220329-1	Zfish	PMID:32902807

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern