Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHMP2A
  • Mouse genes Chmp2a
  • Rat genes Chmp2a
  • Zfish genes chmp2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chmp2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031210	phosphatidylcholine binding	CHMP2A	IMP		Human	PMID:18687924
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:O75351	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9BY43	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9UN37	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9BY43	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9UN37	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9Y3E7	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q8WV92	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9UN37	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9Y3E7	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9NP79	Human	PMID:18385515
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:O75351	Human	PMID:18687924
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9Y3E7	Human	PMID:18687924
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:P53990	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9Y3E7	Human	PMID:19525971
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9Y3E7-1	Human	PMID:19525971
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9NP79	Human	PMID:21543490
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9UN37	Human	PMID:21543490
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9BY43	Human	PMID:21975012
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q8WV92	Human	PMID:23045692
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9H444	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9Y3E7	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9NP79	Human	PMID:23105106
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q8NF50-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q9H444	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:Q8WV92	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHMP2A	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Chmp2a	IPI	PR:P46467	Mouse	PMID:15173323
Molecular Function	GO:0019904	protein domain specific binding	CHMP2A	IPI	UniProtKB:O75351	Human	PMID:17928862
Molecular Function	GO:0019904	protein domain specific binding	CHMP2A	IPI	UniProtKB:Q9UN37	Human	PMID:17928862
Cellular Component	GO:1904930	amphisome membrane	CHMP2A	IDA		Human	PMID:17984323
Cellular Component	GO:0000421	autophagosome membrane	CHMP2A	IDA		Human	PMID:17984323
Cellular Component	GO:0000785	chromatin	CHMP2A	IDA		Human	PMID:28242692
Cellular Component	GO:0005829	cytosol	Chmp2a	IDA		Mouse	PMID:15173323
Cellular Component	GO:0000815	ESCRT III complex	CHMP2A	IDA		Human	PMID:18687924
Cellular Component	GO:0000815	ESCRT III complex	CHMP2A	IDA		Human	PMID:26040712
Cellular Component	GO:0070062	extracellular exosome	CHMP2A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CHMP2A	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CHMP2A	HDA		Human	PMID:23533145
Cellular Component	GO:0000776	kinetochore	CHMP2A	IDA		Human	PMID:26040712
Cellular Component	GO:0005828	kinetochore microtubule	CHMP2A	IDA		Human	PMID:26040712
Cellular Component	GO:0005765	lysosomal membrane	CHMP2A	IDA		Human	PMID:17984323
Cellular Component	GO:0016020	membrane	CHMP2A	HDA		Human	PMID:19946888
Cellular Component	GO:0030117	membrane coat	CHMP2A	IMP		Human	PMID:24878737
Cellular Component	GO:0030496	midbody	CHMP2A	IDA		Human	PMID:26040712
Cellular Component	GO:0032585	multivesicular body membrane	CHMP2A	IDA		Human	PMID:16554368
Cellular Component	GO:0005635	nuclear envelope	CHMP2A	IDA		Human	PMID:26040712
Cellular Component	GO:0005643	nuclear pore	CHMP2A	IDA		Human	PMID:26040713
Cellular Component	GO:0005886	plasma membrane	CHMP2A	IDA		Human	PMID:24878737
Biological Process	GO:0097352	autophagosome maturation	CHMP2A	IMP		Human	PMID:17984323
Biological Process	GO:0006914	autophagy	CHMP2A	IMP		Human	PMID:17984323
Biological Process	GO:0045184	establishment of protein localization	CHMP2A	IMP		Human	PMID:23045692
Biological Process	GO:0010458	exit from mitosis	CHMP2A	IMP		Human	PMID:26040712
Biological Process	GO:1902774	late endosome to lysosome transport	CHMP2A	IMP		Human	PMID:17984323
Biological Process	GO:0010324	membrane invagination	CHMP2A	IMP		Human	PMID:24878737
Biological Process	GO:0061952	midbody abscission	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:0007080	mitotic metaphase plate congression	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:0071985	multivesicular body sorting pathway	CHMP2A	IDA		Human	PMID:16554368
Biological Process	GO:0060548	negative regulation of cell death	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:1903723	negative regulation of centriole elongation	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP2A	IMP		Human	PMID:26040712
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP2A	IMP		Human	PMID:26040713
Biological Process	GO:0006997	nucleus organization	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:0001778	plasma membrane repair	CHMP2A	IDA		Human	PMID:24482116
Biological Process	GO:1903543	positive regulation of exosomal secretion	CHMP2A	IMP		Human	PMID:22660413
Biological Process	GO:0051260	protein homooligomerization	CHMP2A	IMP		Human	PMID:18687924
Biological Process	GO:0051258	protein polymerization	CHMP2A	IMP		Human	PMID:23051622
Biological Process	GO:0051258	protein polymerization	CHMP2A	IMP		Human	PMID:24878737
Biological Process	GO:0010824	regulation of centrosome duplication	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:1901673	regulation of mitotic spindle assembly	CHMP2A	IMP		Human	PMID:20616062
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	CHMP2A	IDA		Human	PMID:17984323
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP2A	IMP		Human	PMID:14505570
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP2A	IDA		Human	PMID:24878737
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP2A	IMP		Human	PMID:23051622
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP2A	IGI	UniProtKB:Q9UQN3	Human	PMID:24107264
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP2A	IDA		Human	PMID:24878737
Biological Process	GO:0019076	viral release from host cell	CHMP2A	IGI	UniProtKB:Q9UQN3	Human	PMID:23051622
Biological Process	GO:0019076	viral release from host cell	CHMP2A	IGI	UniProtKB:Q9Y3E7	Human	PMID:23051622
Biological Process	GO:0019076	viral release from host cell	CHMP2A	IMP		Human	PMID:23051622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern