Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHMP2B
  • Mouse genes Chmp2b
  • Rat genes Chmp2b
  • Zfish genes chmp2ba,chmp2bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chmp2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CHMP2B	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9Y3E7	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9D8B3	Human	PMID:17683935
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9H444	Human	PMID:21975012
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:P0C6X7:PRO_0000037309	Human	PMID:22046132
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:P0C6X7:PRO_0000037316	Human	PMID:22046132
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9H444	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9Y3E7	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP2B	IPI	UniProtKB:Q9H444	Human	PMID:26496610
Molecular Function	GO:0019904	protein domain specific binding	CHMP2B	IPI	UniProtKB:O75351	Human	PMID:17928862
Molecular Function	GO:0019904	protein domain specific binding	CHMP2B	IPI	UniProtKB:Q9UN37	Human	PMID:17928862
Cellular Component	GO:1904930	amphisome membrane	CHMP2B	IDA		Human	PMID:17984323
Cellular Component	GO:0000421	autophagosome membrane	CHMP2B	IDA		Human	PMID:17984323
Cellular Component	GO:0005737	cytoplasm	CHMP2B	IDA		Human	PMID:24878737
Cellular Component	GO:0005737	cytoplasm	CHMP2B	IDA		Human	PMID:25468996
Cellular Component	GO:0005829	cytosol	CHMP2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CHMP2B	IDA		Human	PMID:16041373
Cellular Component	GO:0005768	endosome	CHMP2B	IDA		Human	PMID:24878737
Cellular Component	GO:0000815	ESCRT III complex	CHMP2B	IDA		Human	PMID:24878737
Cellular Component	GO:0070062	extracellular exosome	CHMP2B	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CHMP2B	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	Chmp2b	IDA		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0098978	glutamatergic synapse	Chmp2b	IMP		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0000776	kinetochore	CHMP2B	IDA		Human	PMID:26040712
Cellular Component	GO:0005828	kinetochore microtubule	CHMP2B	IDA		Human	PMID:26040712
Cellular Component	GO:0005770	late endosome	CHMP2B	IDA		Human	PMID:16041373
Cellular Component	GO:0005765	lysosomal membrane	CHMP2B	IDA		Human	PMID:17984323
Cellular Component	GO:0005764	lysosome	CHMP2B	IDA		Human	PMID:16041373
Cellular Component	GO:0030496	midbody	CHMP2B	IDA		Human	PMID:26040712
Cellular Component	GO:0032585	multivesicular body membrane	CHMP2B	IDA		Human	PMID:16554368
Cellular Component	GO:0005643	nuclear pore	CHMP2B	IDA		Human	PMID:26040713
Cellular Component	GO:0005886	plasma membrane	CHMP2B	IDA		Human	PMID:24878737
Cellular Component	GO:0014069	postsynaptic density	Chmp2b	EXP		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0014069	postsynaptic density	Chmp2b	IDA		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0014069	postsynaptic density	Chmp2b	IMP		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0097352	autophagosome maturation	CHMP2B	IMP		Human	PMID:17984323
Biological Process	GO:0006914	autophagy	CHMP2B	IMP		Human	PMID:17984323
Biological Process	GO:0050890	cognition	CHMP2B	IMP		Human	PMID:16041373
Biological Process	GO:0007032	endosome organization	CHMP2B	IMP		Human	PMID:16041373
Biological Process	GO:1902774	late endosome to lysosome transport	CHMP2B	IMP		Human	PMID:17984323
Biological Process	GO:0061952	midbody abscission	CHMP2B	IMP		Human	PMID:20616062
Biological Process	GO:0007080	mitotic metaphase plate congression	CHMP2B	IMP		Human	PMID:20616062
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Chmp2b	IDA		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Chmp2b	IMP		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0071985	multivesicular body sorting pathway	CHMP2B	IDA		Human	PMID:16554368
Biological Process	GO:0060548	negative regulation of cell death	CHMP2B	IMP		Human	PMID:20616062
Biological Process	GO:0070050	neuron cellular homeostasis	CHMP2B	IMP		Human	PMID:16041373
Biological Process	GO:0070050	neuron cellular homeostasis	CHMP2B	IMP		Human	PMID:16807408
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP2B	IMP		Human	PMID:26040713
Biological Process	GO:0006997	nucleus organization	CHMP2B	IMP		Human	PMID:20616062
Biological Process	GO:0001778	plasma membrane repair	CHMP2B	IDA		Human	PMID:24482116
Biological Process	GO:0010824	regulation of centrosome duplication	CHMP2B	IMP		Human	PMID:20616062
Biological Process	GO:1901673	regulation of mitotic spindle assembly	CHMP2B	IMP		Human	PMID:20616062
Biological Process	GO:0099159	regulation of modification of postsynaptic structure	Chmp2b	IDA		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0099159	regulation of modification of postsynaptic structure	Chmp2b	IMP		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0099175	regulation of postsynapse organization	Chmp2b	IDA		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0099175	regulation of postsynapse organization	Chmp2b	IMP		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	CHMP2B	IDA		Human	PMID:17984323
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP2B	IDA		Human	PMID:24878737
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP2B	IMP		Human	PMID:23051622
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP2B	IGI	UniProtKB:O43633	Human	PMID:24107264
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP2B	IDA		Human	PMID:24878737
Biological Process	GO:0019076	viral release from host cell	CHMP2B	IGI	UniProtKB:O43633	Human	PMID:23051622
Biological Process	GO:0019076	viral release from host cell	CHMP2B	IGI	UniProtKB:Q9Y3E7	Human	PMID:23051622
Biological Process	GO:0019076	viral release from host cell	CHMP2B	IMP		Human	PMID:23051622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern