Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHMP4B
  • Mouse genes Chmp4b
  • Rat genes Chmp4b,Chmp4bl1
  • Zfish genes chmp4ba,chmp4bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chmp4b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CHMP4B	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	CHMP4B	IPI	UniProtKB:Q9H444	Human	PMID:16730941
Molecular Function	GO:0042802	identical protein binding	CHMP4B	IPI	UniProtKB:Q9H444	Human	PMID:18209100
Molecular Function	GO:0042802	identical protein binding	CHMP4B	IPI	UniProtKB:Q9H444	Human	PMID:19523902
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:12860994
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q96CF2	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q96FZ7	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q96CF2	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q96FZ7	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9BY43	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:P63279	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:O95630	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:P63279	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q6P1N0	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9BY43	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9NZZ3	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9Y3E7	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUX9	Human	PMID:16856878
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9H3S7	Human	PMID:17174262
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:O95630	Human	PMID:17711858
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:18434552
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9H3S7	Human	PMID:18434552
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:18511562
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:18641129
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9WU78-1	Human	PMID:19523902
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q6DKK2	Human	PMID:20208530
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9UN37	Human	PMID:21543490
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:21889351
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9UQN3	Human	PMID:21975012
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q5VW32	Human	PMID:22162750
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q5VW32	Human	PMID:22484091
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:22484091
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:O43633	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9UQN3	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9Y3E7	Human	PMID:23051622
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:O43633	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q6P1N0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q8WUM4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9NZZ3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9UQN3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9Y3E7	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:O60664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q9BY43-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHMP4B	IPI	UniProtKB:Q5VW32	Human	PMID:34818527
Molecular Function	GO:0005515	protein binding	Chmp4b	IPI	UniProtKB:Q8WUM4	Mouse	MGI:MGI:5705193|PMID:26496610
Molecular Function	GO:0005515	protein binding	Chmp4b	IPI	UniProtKB:Q8WUM4	Mouse	MGI:MGI:5914142|PMID:25686249
Molecular Function	GO:0005515	protein binding	Chmp4b	IPI	UniProtKB:Q9UQN3	Mouse	MGI:MGI:3851235|PMID:17683935
Molecular Function	GO:0042803	protein homodimerization activity	CHMP4B	IPI	UniProtKB:Q9H444	Human	PMID:14519844
Cellular Component	GO:1904930	amphisome membrane	CHMP4B	IDA		Human	PMID:17984323
Cellular Component	GO:0000421	autophagosome membrane	CHMP4B	IDA		Human	PMID:17984323
Cellular Component	GO:0005737	cytoplasm	CHMP4B	IDA		Human	PMID:17701905
Cellular Component	GO:0005737	cytoplasm	CHMP4B	IDA		Human	PMID:21975012
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	CHMP4B	IDA		Human	PMID:18209100
Cellular Component	GO:0005829	cytosol	Chmp4b	IDA		Mouse	MGI:MGI:3851235|PMID:17683935
Cellular Component	GO:0005768	endosome	CHMP4B	IDA		Human	PMID:17701905
Cellular Component	GO:0000815	ESCRT III complex	CHMP4B	IDA		Human	PMID:18209100
Cellular Component	GO:0000815	ESCRT III complex	CHMP4B	IDA		Human	PMID:21310966
Cellular Component	GO:0000815	ESCRT III complex	CHMP4B	IDA		Human	PMID:21975012
Cellular Component	GO:0000815	ESCRT III complex	CHMP4B	IDA		Human	PMID:24878737
Cellular Component	GO:0000815	ESCRT III complex	CHMP4B	IDA		Human	PMID:26040712
Cellular Component	GO:0070062	extracellular exosome	CHMP4B	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CHMP4B	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CHMP4B	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	Chmp4bl1	IDA		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0098978	glutamatergic synapse	Chmp4bl1	IMP		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0000776	kinetochore	CHMP4B	IDA		Human	PMID:26040712
Cellular Component	GO:0005828	kinetochore microtubule	CHMP4B	IDA		Human	PMID:26040712
Cellular Component	GO:0005765	lysosomal membrane	CHMP4B	IDA		Human	PMID:17984323
Cellular Component	GO:0016020	membrane	Chmp4b	IDA		Mouse	MGI:MGI:3851235|PMID:17683935
Cellular Component	GO:0030117	membrane coat	CHMP4B	IDA		Human	PMID:24878737
Cellular Component	GO:0030496	midbody	CHMP4B	IDA		Human	PMID:21310966
Cellular Component	GO:0030496	midbody	CHMP4B	IDA		Human	PMID:22724069
Cellular Component	GO:0030496	midbody	CHMP4B	IDA		Human	PMID:26040712
Cellular Component	GO:0032585	multivesicular body membrane	CHMP4B	IDA		Human	PMID:16554368
Cellular Component	GO:0005635	nuclear envelope	CHMP4B	IDA		Human	PMID:26040712
Cellular Component	GO:0005643	nuclear pore	CHMP4B	IDA		Human	PMID:26040713
Cellular Component	GO:0005634	nucleus	CHMP4B	IDA		Human	PMID:21975012
Cellular Component	GO:0005634	nucleus	Chmp4b	IDA		Mouse	MGI:MGI:3851235|PMID:17683935
Cellular Component	GO:0005886	plasma membrane	CHMP4B	IDA		Human	PMID:24878737
Cellular Component	GO:0014069	postsynaptic density	Chmp4bl1	IDA		Rat	PMID:25698751|RGD:13702150
Cellular Component	GO:0031982	vesicle	CHMP4B	IDA		Human	PMID:25468996
Biological Process	GO:0097352	autophagosome maturation	CHMP4B	IMP		Human	PMID:17984323
Biological Process	GO:0006914	autophagy	CHMP4B	IMP		Human	PMID:17984323
Biological Process	GO:0006914	autophagy	CHMP4B	IMP		Human	PMID:24095276
Biological Process	GO:0060271	cilium assembly	chmp4ba	IGI	ZFIN:ZDB-MRPHLNO-200721-5,ZFIN:ZDB-MRPHLNO-200721-4	Zfish	PMID:31914703
Biological Process	GO:0060271	cilium assembly	chmp4bb	IGI	ZFIN:ZDB-MRPHLNO-200721-5,ZFIN:ZDB-MRPHLNO-200721-4	Zfish	PMID:31914703
Biological Process	GO:0010458	exit from mitosis	CHMP4B	IMP		Human	PMID:26040712
Biological Process	GO:1902774	late endosome to lysosome transport	CHMP4B	IMP		Human	PMID:17984323
Biological Process	GO:0036438	maintenance of lens transparency	CHMP4B	IMP		Human	PMID:17701905
Biological Process	GO:0090148	membrane fission	CHMP4B	IMP		Human	PMID:21310966
Biological Process	GO:0061952	midbody abscission	CHMP4B	IMP		Human	PMID:20616062
Biological Process	GO:0000281	mitotic cytokinesis	CHMP4B	IMP		Human	PMID:21310966
Biological Process	GO:0007080	mitotic metaphase plate congression	CHMP4B	IMP		Human	PMID:20616062
Biological Process	GO:0071985	multivesicular body sorting pathway	CHMP4B	IDA		Human	PMID:16554368
Biological Process	GO:1902902	negative regulation of autophagosome assembly	CHMP4B	IMP		Human	PMID:21975012
Biological Process	GO:0060548	negative regulation of cell death	CHMP4B	IMP		Human	PMID:20616062
Biological Process	GO:1901215	negative regulation of neuron death	CHMP4B	IMP		Human	PMID:21975012
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP4B	IMP		Human	PMID:26040712
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP4B	IMP		Human	PMID:26040713
Biological Process	GO:0006997	nucleus organization	CHMP4B	IMP		Human	PMID:20616062
Biological Process	GO:0001778	plasma membrane repair	CHMP4B	IDA		Human	PMID:24482116
Biological Process	GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	CHMP4B	IMP		Human	PMID:21975012
Biological Process	GO:0051258	protein polymerization	CHMP4B	IDA		Human	PMID:18209100
Biological Process	GO:0010506	regulation of autophagy	Chmp4b	IMP		Mouse	MGI:MGI:3851235|PMID:17683935
Biological Process	GO:0010824	regulation of centrosome duplication	CHMP4B	IMP		Human	PMID:20616062
Biological Process	GO:1901673	regulation of mitotic spindle assembly	CHMP4B	IMP		Human	PMID:20616062
Biological Process	GO:0099175	regulation of postsynapse organization	Chmp4bl1	IDA		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0099175	regulation of postsynapse organization	Chmp4bl1	IMP		Rat	PMID:25698751|RGD:13702150
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	CHMP4B	IDA		Human	PMID:17984323
Biological Process	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	CHMP4B	IMP		Human	PMID:22547407
Biological Process	GO:0046755	viral budding	CHMP4B	IMP		Human	PMID:17701905
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP4B	IMP		Human	PMID:14505570
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP4B	IDA		Human	PMID:24878737
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP4B	IGI	UniProtKB:Q8WUM4	Human	PMID:24107264
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP4B	IGI	UniProtKB:Q9BY43	Human	PMID:24107264
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP4B	IDA		Human	PMID:24878737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern