Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHMP5
  • Mouse genes Chmp5
  • Rat genes Chmp5
  • Zfish genes chmp5a,chmp5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chmp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CHMP5	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9NP79	Human	PMID:15644320
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9H444	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9NP79	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:O95630	Human	PMID:17711858
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9NP79	Human	PMID:18385515
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9NP79	Human	PMID:21543490
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:O95630	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9NP79	Human	PMID:23105106
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:O75351	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q8WV92	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9H444	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9HC29	Human	PMID:27812135
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:Q9NP79	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CHMP5	IPI	UniProtKB:O75351	Human	PMID:32296183
Cellular Component	GO:1904930	amphisome membrane	CHMP5	IDA		Human	PMID:17984323
Cellular Component	GO:0000421	autophagosome membrane	CHMP5	IDA		Human	PMID:17984323
Cellular Component	GO:0005829	cytosol	CHMP5	IDA		Human	PMID:15644320
Cellular Component	GO:0070062	extracellular exosome	CHMP5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CHMP5	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CHMP5	HDA		Human	PMID:23533145
Cellular Component	GO:0000776	kinetochore	CHMP5	IDA		Human	PMID:26040712
Cellular Component	GO:0005828	kinetochore microtubule	CHMP5	IDA		Human	PMID:26040712
Cellular Component	GO:0005765	lysosomal membrane	CHMP5	IDA		Human	PMID:17984323
Cellular Component	GO:0030496	midbody	CHMP5	IDA		Human	PMID:26040712
Cellular Component	GO:0032585	multivesicular body membrane	CHMP5	IDA		Human	PMID:16554368
Cellular Component	GO:0005643	nuclear pore	CHMP5	IDA		Human	PMID:26040713
Cellular Component	GO:0005634	nucleus	Chmp5	IDA		Mouse	PMID:11555636
Cellular Component	GO:0005886	plasma membrane	CHMP5	IDA		Human	PMID:24878737
Biological Process	GO:0097352	autophagosome maturation	CHMP5	IMP		Human	PMID:17984323
Biological Process	GO:0006914	autophagy	CHMP5	IMP		Human	PMID:17984323
Biological Process	GO:0071222	cellular response to lipopolysaccharide	CHMP5	IMP		Human	PMID:27812135
Biological Process	GO:0071225	cellular response to muramyl dipeptide	CHMP5	IMP		Human	PMID:27812135
Biological Process	GO:0008333	endosome to lysosome transport	Chmp5	IMP	MGI:MGI:3626293	Mouse	PMID:16567502
Biological Process	GO:1902774	late endosome to lysosome transport	CHMP5	IMP		Human	PMID:17984323
Biological Process	GO:0007040	lysosome organization	Chmp5	IMP	MGI:MGI:3626293	Mouse	PMID:16567502
Biological Process	GO:0061952	midbody abscission	CHMP5	IMP		Human	PMID:20616062
Biological Process	GO:0007080	mitotic metaphase plate congression	CHMP5	IMP		Human	PMID:20616062
Biological Process	GO:0071985	multivesicular body sorting pathway	CHMP5	IMP		Human	PMID:15644320
Biological Process	GO:0071985	multivesicular body sorting pathway	CHMP5	IDA		Human	PMID:16554368
Biological Process	GO:0060548	negative regulation of cell death	CHMP5	IMP		Human	PMID:20616062
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP5	IMP		Human	PMID:26040713
Biological Process	GO:0006997	nucleus organization	CHMP5	IMP		Human	PMID:20616062
Biological Process	GO:0001778	plasma membrane repair	CHMP5	IDA		Human	PMID:24482116
Biological Process	GO:0010824	regulation of centrosome duplication	CHMP5	IMP		Human	PMID:20616062
Biological Process	GO:1901673	regulation of mitotic spindle assembly	CHMP5	IMP		Human	PMID:20616062
Biological Process	GO:0001919	regulation of receptor recycling	Chmp5	IMP		Mouse	PMID:16567502
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	CHMP5	IDA		Human	PMID:17984323
Biological Process	GO:0046755	viral budding	CHMP5	IMP		Human	PMID:15644320
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP5	IDA		Human	PMID:24878737
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP5	IDA		Human	PMID:24878737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern