Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHMP6
  • Mouse genes Chmp6
  • Rat genes Chmp6
  • Zfish genes chmp6a,chmp6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chmp6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BRG1	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9H444	Human	PMID:14505570
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q86VN1	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q96CF2	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q96H20	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BRG1	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BY43	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9H444	Human	PMID:14519844
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BRG1	Human	PMID:16730941
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BRG1	Human	PMID:16856878
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BRG1	Human	PMID:16973552
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9UN37	Human	PMID:18606141
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9UN37	Human	PMID:21543490
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q9BRG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:O14656-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CHMP6	IPI	UniProtKB:Q16637	Human	PMID:32814053
Molecular Function	GO:0044877	protein-containing complex binding	CHMP6	IDA		Human	PMID:16973552
Cellular Component	GO:1904930	amphisome membrane	CHMP6	IDA		Human	PMID:17984323
Cellular Component	GO:0000421	autophagosome membrane	CHMP6	IDA		Human	PMID:17984323
Cellular Component	GO:0010008	endosome membrane	CHMP6	IDA		Human	PMID:16973552
Cellular Component	GO:0000815	ESCRT III complex	CHMP6	IDA		Human	PMID:24878737
Cellular Component	GO:0070062	extracellular exosome	CHMP6	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CHMP6	HDA		Human	PMID:20458337
Cellular Component	GO:0000776	kinetochore	CHMP6	IDA		Human	PMID:26040712
Cellular Component	GO:0005828	kinetochore microtubule	CHMP6	IDA		Human	PMID:26040712
Cellular Component	GO:0005765	lysosomal membrane	CHMP6	IDA		Human	PMID:17984323
Cellular Component	GO:0016020	membrane	CHMP6	HDA		Human	PMID:19946888
Cellular Component	GO:0030496	midbody	CHMP6	IDA		Human	PMID:26040712
Cellular Component	GO:0032585	multivesicular body membrane	CHMP6	IDA		Human	PMID:16554368
Cellular Component	GO:0005643	nuclear pore	CHMP6	IDA		Human	PMID:26040713
Cellular Component	GO:0005886	plasma membrane	CHMP6	IDA		Human	PMID:24878737
Biological Process	GO:0097352	autophagosome maturation	CHMP6	IMP		Human	PMID:17984323
Biological Process	GO:0006914	autophagy	CHMP6	IMP		Human	PMID:17984323
Biological Process	GO:1902774	late endosome to lysosome transport	CHMP6	IMP		Human	PMID:17984323
Biological Process	GO:0061952	midbody abscission	CHMP6	IMP		Human	PMID:20616062
Biological Process	GO:0007080	mitotic metaphase plate congression	CHMP6	IMP		Human	PMID:20616062
Biological Process	GO:0071985	multivesicular body sorting pathway	CHMP6	IDA		Human	PMID:16554368
Biological Process	GO:0060548	negative regulation of cell death	CHMP6	IMP		Human	PMID:20616062
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	CHMP6	IMP		Human	PMID:16973552
Biological Process	GO:0031468	nuclear membrane reassembly	CHMP6	IMP		Human	PMID:26040713
Biological Process	GO:0006997	nucleus organization	CHMP6	IMP		Human	PMID:20616062
Biological Process	GO:0001778	plasma membrane repair	CHMP6	IDA		Human	PMID:24482116
Biological Process	GO:1901673	regulation of mitotic spindle assembly	CHMP6	IMP		Human	PMID:20616062
Biological Process	GO:0042176	regulation of protein catabolic process	CHMP6	IMP		Human	PMID:18606141
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	CHMP6	IDA		Human	PMID:17984323
Biological Process	GO:0046761	viral budding from plasma membrane	CHMP6	IDA		Human	PMID:24878737
Biological Process	GO:0039702	viral budding via host ESCRT complex	CHMP6	IDA		Human	PMID:24878737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern