Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHRM1
  • Mouse genes Chrm1
  • Rat genes Chrm1
  • Zfish genes chrm1a,chrm1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016907	G protein-coupled acetylcholine receptor activity	Chrm1	IDA		Rat	PMID:12534975|RGD:724727
Molecular Function	GO:0005515	protein binding	CHRM1	IPI	UniProtKB:Q9BVK8	Human	PMID:21056967
Cellular Component	GO:0032279	asymmetric synapse	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0043679	axon terminus	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0098981	cholinergic synapse	Chrm1	IDA		Mouse	PMID:20335477
Cellular Component	GO:0030425	dendrite	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0098978	glutamatergic synapse	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0016020	membrane	Chrm1	IDA		Rat	PMID:8320877|RGD:2303388
Cellular Component	GO:0014069	postsynaptic density	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0098839	postsynaptic density membrane	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0045211	postsynaptic membrane	Chrm1	IDA		Mouse	PMID:20335477
Cellular Component	GO:0042734	presynaptic membrane	Chrm1	IDA		Rat	PMID:8182478|RGD:2303389
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Chrm1	EXP		Mouse	PMID:26472558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Chrm1	IDA		Mouse	PMID:26472558
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Chrm1	IMP		Mouse	PMID:26472558
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	Chrm1	IDA		Rat	PMID:12534975|RGD:724727
Biological Process	GO:0007274	neuromuscular synaptic transmission	Chrm1	IDA		Rat	PMID:12534975|RGD:724727
Biological Process	GO:0090316	positive regulation of intracellular protein transport	Chrm1	IDA		Rat	PMID:17908240|RGD:7242040
Biological Process	GO:0043270	positive regulation of monoatomic ion transport	CHRM1	IGI	UniProtKB:Q9JJH7	Human	PMID:14657398
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Chrm1	IMP		Mouse	PMID:26472558
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Chrm1	EXP		Mouse	PMID:26472558
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Chrm1	IDA		Mouse	PMID:26472558
Biological Process	GO:0040012	regulation of locomotion	Chrm1	IMP	MGI:MGI:2158743	Mouse	PMID:11752469
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Chrm1	IMP		Mouse	PMID:26472558
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Chrm1	IDA		Mouse	PMID:26472558
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Chrm1	EXP		Mouse	PMID:26472558

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern