Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHRNB1
  • Mouse genes Chrnb1
  • Rat genes Chrnb1
  • Zfish genes chrnb1,chrnb1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042166	acetylcholine binding	Chrnb1	IMP		Mouse	MGI:MGI:3799559|PMID:8872460
Molecular Function	GO:0015464	acetylcholine receptor activity	CHRNB1	IMP		Human	PMID:8651643
Molecular Function	GO:0015464	acetylcholine receptor activity	CHRNB1	IMP		Human	PMID:8872460
Molecular Function	GO:0015464	acetylcholine receptor activity	chrnb1l	IDA		Zfish	PMID:22580045
Molecular Function	GO:0015464	acetylcholine receptor activity	chrnb1	IDA		Zfish	PMID:22580045
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IGI	MGI:MGI:87893	Mouse	PMID:8798466
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IGI	MGI:MGI:87893	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IGI	MGI:MGI:87895	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IGI	MGI:MGI:87894	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IGI	MGI:MGI:87895	Mouse	PMID:8798466
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IDA		Rat	PMID:1702709|RGD:68734
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb1	IDA		Rat	PMID:22461452|RGD:8549758
Molecular Function	GO:0015267	channel activity	CHRNB1	IMP		Human	PMID:8872460
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	Chrnb1	IDA		Rat	PMID:1702709|RGD:68734
Molecular Function	GO:0005515	protein binding	CHRNB1	IPI	UniProtKB:Q9NWX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Chrnb1	IPI	PR:P35564	Mouse	PMID:8798466
Molecular Function	GO:0005515	protein binding	Chrnb1	IPI	PR:P04760	Mouse	PMID:8798466
Molecular Function	GO:0005515	protein binding	Chrnb1	IPI	PR:P02716	Mouse	PMID:8798466
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNB1	IDA		Human	PMID:7531341
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNB1	IMP		Human	PMID:7531341
Cellular Component	GO:0005892	acetylcholine-gated channel complex	CHRNB1	IMP		Human	PMID:8872460
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb1	IPI		Mouse	MGI:MGI:6828906|PMID:8334706
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb1	IDA		Mouse	PMID:8798466
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb1	IDA		Rat	PMID:22461452|RGD:8549758
Cellular Component	GO:0005892	acetylcholine-gated channel complex	chrnb1l	IDA		Zfish	PMID:22580045
Cellular Component	GO:0005892	acetylcholine-gated channel complex	chrnb1	IDA		Zfish	PMID:22580045
Cellular Component	GO:0031594	neuromuscular junction	CHRNB1	IDA		Human	PMID:7531341
Cellular Component	GO:0031594	neuromuscular junction	CHRNB1	IMP		Human	PMID:7531341
Cellular Component	GO:0031594	neuromuscular junction	Chrnb1	IDA		Mouse	PMID:4781450
Cellular Component	GO:0005886	plasma membrane	Chrnb1	IDA		Mouse	PMID:12388596
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrnb1	IDA		Mouse	PMID:4781450
Cellular Component	GO:0045202	synapse	CHRNB1	IMP		Human	PMID:8872460
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Chrnb1	IDA		Mouse	MGI:MGI:6850201|PMID:15864502
Biological Process	GO:0035095	behavioral response to nicotine	CHRNB1	IMP		Human	PMID:16874522
Biological Process	GO:0006812	monoatomic cation transport	CHRNB1	IMP		Human	PMID:8872460
Biological Process	GO:0006812	monoatomic cation transport	Chrnb1	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0055001	muscle cell development	CHRNB1	IMP		Human	PMID:8651643
Biological Process	GO:0006936	muscle contraction	CHRNB1	IMP		Human	PMID:8651643
Biological Process	GO:0050877	nervous system process	CHRNB1	IMP		Human	PMID:11104662
Biological Process	GO:0007274	neuromuscular synaptic transmission	CHRNB1	IMP		Human	PMID:8651643
Biological Process	GO:0001941	postsynaptic membrane organization	CHRNB1	IMP		Human	PMID:8651643
Biological Process	GO:0042391	regulation of membrane potential	Chrnb1	IGI	MGI:MGI:87893	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnb1	IGI	MGI:MGI:87895	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnb1	IGI	MGI:MGI:87895	Mouse	PMID:8798466
Biological Process	GO:0042391	regulation of membrane potential	Chrnb1	IGI	MGI:MGI:87894	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnb1	IGI	MGI:MGI:87893	Mouse	PMID:8798466
Biological Process	GO:0042391	regulation of membrane potential	Chrnb1	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Biological Process	GO:0007165	signal transduction	CHRNB1	IMP		Human	PMID:8872460
Biological Process	GO:0003009	skeletal muscle contraction	Chrnb1	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0007271	synaptic transmission, cholinergic	CHRNB1	IMP		Human	PMID:8872460
Biological Process	GO:0007271	synaptic transmission, cholinergic	chrnb1	IDA		Zfish	PMID:21844221

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern