Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Chrnb2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CHRNB2
- Mouse genes Chrnb2
- Rat genes Chrnb2
- Zfish genes chrnb2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrnb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042166	acetylcholine binding	CHRNB2	IMP		Human	PMID:15964197
Molecular Function	GO:0042166	acetylcholine binding	Chrnb2	IDA		Rat	PMID:9030613\|RGD:2303190
Molecular Function	GO:0015464	acetylcholine receptor activity	CHRNB2	IDA		Human	PMID:8906617
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNB2	IDA		Human	PMID:18387948
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	CHRNB2	IDA		Human	PMID:8906617
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IDA		Mouse	PMID:17470777
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IDA		Mouse	PMID:9614223
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IGI	MGI:MGI:87888	Mouse	PMID:15569257
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IGI	MGI:MGI:87888	Mouse	PMID:15741168
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11222635
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IMP		Rat	PMID:11259617\|RGD:8549520
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IDA		Rat	PMID:11956333\|RGD:727635
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnb2	IGI	UniProtKB:P04757	Rat	PMID:21540349\|RGD:12790638
Molecular Function	GO:1901363	heterocyclic compound binding	Chrnb2	IPI	CHEBI:4803	Rat	PMID:16129735\|RGD:2303195
Molecular Function	GO:1901363	heterocyclic compound binding	Chrnb2	IDA		Rat	PMID:22550286\|RGD:8549526
Molecular Function	GO:1901363	heterocyclic compound binding	Chrnb2	IDA		Rat	PMID:15016836\|RGD:2303194
Molecular Function	GO:0005515	protein binding	CHRNB2	IPI	UniProtKB:Q86Y78	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	CHRNB2	IPI	UniProtKB:P43681-1	Human	PMID:29720657
Molecular Function	GO:0005515	protein binding	CHRNB2	IPI	UniProtKB:P30532	Human	PMID:8663494
Molecular Function	GO:0005515	protein binding	Chrnb2	IPI	PR:Q9R0W9	Mouse	PMID:12944511
Molecular Function	GO:0005515	protein binding	Chrnb2	IPI	PR:O70174	Mouse	PMID:12944511
Molecular Function	GO:0005515	protein binding	Chrnb2	IPI	UniProtKB:P09483	Rat	PMID:20566638\|RGD:10047290
Molecular Function	GO:0044877	protein-containing complex binding	Chrnb2	IDA		Rat	PMID:20796176\|RGD:8549534
Molecular Function	GO:0050997	quaternary ammonium group binding	Chrnb2	IDA		Rat	PMID:15016836\|RGD:2303194
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Chrnb2	IMP		Mouse	PMID:23811311
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Chrnb2	IDA		Mouse	PMID:23811311
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Chrnb2	EXP		Rat	PMID:15044058\|RGD:1600975
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Chrnb2	IDA		Rat	PMID:15044058\|RGD:1600975
Cellular Component	GO:0005892	acetylcholine-gated channel complex	CHRNB2	IDA		Human	PMID:8906617
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IPI		Mouse	MGI:MGI:6810690\|PMID:22039094
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IDA		Mouse	PMID:12944511
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IDA		Mouse	PMID:26276394
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IDA		Rat	PMID:11259617\|RGD:8549520
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IDA		Rat	PMID:11956333\|RGD:727635
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IDA		Rat	PMID:20796176\|RGD:8549534
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IDA		Rat	PMID:9030613\|RGD:2303190
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnb2	IGI	UniProtKB:P04757	Rat	PMID:21540349\|RGD:12790638
Cellular Component	GO:0098981	cholinergic synapse	Chrnb2	IMP		Mouse	PMID:23811311
Cellular Component	GO:0098981	cholinergic synapse	Chrnb2	IDA		Mouse	PMID:23811311
Cellular Component	GO:0098981	cholinergic synapse	Chrnb2	IDA		Mouse	PMID:12079404
Cellular Component	GO:0098981	cholinergic synapse	Chrnb2	EXP		Rat	PMID:15044058\|RGD:1600975
Cellular Component	GO:0098981	cholinergic synapse	Chrnb2	IDA		Rat	PMID:15044058\|RGD:1600975
Cellular Component	GO:0098981	cholinergic synapse	Chrnb2	IDA		Rat	PMID:3380297\|RGD:13702334
Cellular Component	GO:0098691	dopaminergic synapse	Chrnb2	IDA		Mouse	PMID:11145999
Cellular Component	GO:0098691	dopaminergic synapse	Chrnb2	IMP		Mouse	PMID:11145999
Cellular Component	GO:0098691	dopaminergic synapse	Chrnb2	IDA		Mouse	PMID:12944511
Cellular Component	GO:0098691	dopaminergic synapse	Chrnb2	IMP		Mouse	PMID:12944511
Cellular Component	GO:0009897	external side of plasma membrane	Chrnb2	IDA		Mouse	PMID:15963492
Cellular Component	GO:0016020	membrane	Chrnb2	IDA		Rat	PMID:16129735\|RGD:2303195
Cellular Component	GO:0005886	plasma membrane	Chrnb2	IDA		Mouse	PMID:26276394
Cellular Component	GO:0005886	plasma membrane	Chrnb2	IDA		Mouse	PMID:15741168
Cellular Component	GO:0005886	plasma membrane	Chrnb2	IDA		Rat	PMID:12748066\|RGD:1600980
Cellular Component	GO:0005886	plasma membrane	Chrnb2	IDA		Rat	PMID:19474315\|RGD:8554250
Cellular Component	GO:0044853	plasma membrane raft	Chrnb2	IGI	UniProtKB:P04757	Rat	PMID:21540349\|RGD:12790638
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrnb2	IDA		Mouse	PMID:12079404
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrnb2	IDA		Rat	PMID:3380297\|RGD:13702334
Cellular Component	GO:0042734	presynaptic membrane	Chrnb2	IDA		Mouse	PMID:24607281
Cellular Component	GO:0042734	presynaptic membrane	Chrnb2	IEP		Mouse	PMID:24607281
Cellular Component	GO:0042734	presynaptic membrane	Chrnb2	IDA		Rat	PMID:24607281\|RGD:13702281
Cellular Component	GO:0032991	protein-containing complex	Chrnb2	IDA		Rat	PMID:16129735\|RGD:2303195
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Chrnb2	IDA		Mouse	PMID:26276394
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Chrnb2	IGI	UniProtKB:P04757	Rat	PMID:21540349\|RGD:12790638
Biological Process	GO:0001508	action potential	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15456819
Biological Process	GO:0008306	associative learning	Chrnb2	IGI	MGI:MGI:99779	Mouse	PMID:15541879
Biological Process	GO:0042113	B cell activation	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:16253349
Biological Process	GO:0042113	B cell activation	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15963492
Biological Process	GO:0042100	B cell proliferation	Chrnb2	IGI	MGI:MGI:88336	Mouse	PMID:15963492
Biological Process	GO:0035095	behavioral response to nicotine	CHRNB2	IMP		Human	PMID:17559419
Biological Process	GO:0035095	behavioral response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11955523
Biological Process	GO:0035095	behavioral response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:17470777
Biological Process	GO:0035095	behavioral response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15464132
Biological Process	GO:0035095	behavioral response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:12876201
Biological Process	GO:0035095	behavioral response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:16965547
Biological Process	GO:0006816	calcium ion transport	Chrnb2	IGI	MGI:MGI:87888	Mouse	PMID:15569257
Biological Process	GO:0021955	central nervous system neuron axonogenesis	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:12097474
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11344259
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:15608630
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:14687550
Biological Process	GO:0050890	cognition	CHRNB2	IMP		Human	PMID:17559419
Biological Process	GO:0001661	conditioned taste aversion	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11955523
Biological Process	GO:0014046	dopamine secretion	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:9428762
Biological Process	GO:0051649	establishment of localization in cell	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:9428762
Biological Process	GO:0021771	lateral geniculate nucleus development	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:12097474
Biological Process	GO:0007612	learning	CHRNB2	IMP		Human	PMID:15964197
Biological Process	GO:0007612	learning	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11044747
Biological Process	GO:0007626	locomotory behavior	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:9428762
Biological Process	GO:0051899	membrane depolarization	Chrnb2	IDA		Mouse	MGI:MGI:6810694\|PMID:24144909
Biological Process	GO:0051899	membrane depolarization	Chrnb2	IDA		Mouse	MGI:MGI:6810690\|PMID:22039094
Biological Process	GO:0051899	membrane depolarization	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11222635
Biological Process	GO:0051899	membrane depolarization	Chrnb2	IDA		Rat	PMID:19176801\|RGD:150521628
Biological Process	GO:0007613	memory	CHRNB2	IMP		Human	PMID:15964197
Biological Process	GO:0007613	memory	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:7870173
Biological Process	GO:1904456	negative regulation of neuronal action potential	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15456819
Biological Process	GO:0050877	nervous system process	CHRNB2	IMP		Human	PMID:17900292
Biological Process	GO:0019228	neuronal action potential	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:10235262
Biological Process	GO:0019228	neuronal action potential	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15456819
Biological Process	GO:0019228	neuronal action potential	Chrnb2	IGI	MGI:MGI:87892	Mouse	PMID:10531434
Biological Process	GO:0021631	optic nerve morphogenesis	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:12097474
Biological Process	GO:0021631	optic nerve morphogenesis	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11344259
Biological Process	GO:0030890	positive regulation of B cell proliferation	Chrnb2	IGI	MGI:MGI:88336	Mouse	PMID:15963492
Biological Process	GO:0033603	positive regulation of dopamine secretion	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:9428762
Biological Process	GO:0032226	positive regulation of synaptic transmission, dopaminergic	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15464132
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Chrnb2	IDA		Mouse	PMID:11145999
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Chrnb2	IMP		Mouse	PMID:11145999
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Chrnb2	IMP		Mouse	PMID:12944511
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Chrnb2	IDA		Mouse	PMID:12944511
Biological Process	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15215293
Biological Process	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15215293
Biological Process	GO:0048814	regulation of dendrite morphogenesis	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:11027228
Biological Process	GO:0042053	regulation of dopamine metabolic process	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11282258
Biological Process	GO:0014059	regulation of dopamine secretion	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:12944511
Biological Process	GO:0042391	regulation of membrane potential	Chrnb2	IGI	MGI:MGI:87888	Mouse	PMID:15569257
Biological Process	GO:0042391	regulation of membrane potential	Chrnb2	IGI	MGI:MGI:87892	Mouse	PMID:10531434
Biological Process	GO:0042391	regulation of membrane potential	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:9428762
Biological Process	GO:0042391	regulation of membrane potential	Chrnb2	IGI	MGI:MGI:87888	Mouse	PMID:15741168
Biological Process	GO:0051963	regulation of synapse assembly	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:17301182
Biological Process	GO:0032225	regulation of synaptic transmission, dopaminergic	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:16772172
Biological Process	GO:1905144	response to acetylcholine	Chrnb2	IDA		Rat	PMID:15016836\|RGD:2303194
Biological Process	GO:1905144	response to acetylcholine	Chrnb2	IGI	UniProtKB:P04757	Rat	PMID:21540349\|RGD:12790638
Biological Process	GO:0042220	response to cocaine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11282258
Biological Process	GO:0045471	response to ethanol	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:15489024
Biological Process	GO:0001666	response to hypoxia	CHRNB2	IDA		Human	PMID:12189247
Biological Process	GO:0001666	response to hypoxia	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15450117
Biological Process	GO:0035094	response to nicotine	CHRNB2	IDA		Human	PMID:12189247
Biological Process	GO:0035094	response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15215293
Biological Process	GO:0035094	response to nicotine	Chrnb2	IGI	MGI:MGI:87892	Mouse	PMID:10531434
Biological Process	GO:0035094	response to nicotine	Chrnb2	IGI	MGI:MGI:87888	Mouse	PMID:15741168
Biological Process	GO:0035094	response to nicotine	Chrnb2	IMP	MGI:MGI:2158714	Mouse	PMID:15489024
Biological Process	GO:0035094	response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:10235262
Biological Process	GO:0035094	response to nicotine	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:9428762
Biological Process	GO:0035094	response to nicotine	Chrnb2	IGI	MGI:MGI:99779	Mouse	PMID:17470777
Biological Process	GO:0035094	response to nicotine	Chrnb2	IMP		Rat	PMID:14764595\|RGD:1358636
Biological Process	GO:0019233	sensory perception of pain	Chrnb2	IMP	MGI:MGI:1926251	Mouse	PMID:10235262
Biological Process	GO:0007605	sensory perception of sound	Chrnb2	IMP		Mouse	PMID:15788760
Biological Process	GO:0007165	signal transduction	CHRNB2	IDA		Human	PMID:8906617
Biological Process	GO:0006939	smooth muscle contraction	Chrnb2	IGI	MGI:MGI:87892	Mouse	PMID:10531434
Biological Process	GO:0035176	social behavior	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:12876201
Biological Process	GO:0060084	synaptic transmission involved in micturition	Chrnb2	IGI	MGI:MGI:87892	Mouse	PMID:10531434
Biological Process	GO:0007271	synaptic transmission, cholinergic	Chrnb2	IMP		Rat	PMID:12754307\|RGD:1358637
Biological Process	GO:0021562	vestibulocochlear nerve development	Chrnb2	IMP		Mouse	PMID:15788760
Biological Process	GO:0008542	visual learning	CHRNB2	IMP		Human	PMID:15964197
Biological Process	GO:0008542	visual learning	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:10064590
Biological Process	GO:0008542	visual learning	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:12876201
Biological Process	GO:0007601	visual perception	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:15456819
Biological Process	GO:0007601	visual perception	Chrnb2	IMP	MGI:MGI:1926253	Mouse	PMID:11344259

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.