Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHRND
  • Mouse genes Chrnd
  • Rat genes Chrnd
  • Zfish genes chrnd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrnd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042166	acetylcholine binding	Chrnd	IGI	MGI:MGI:87885	Mouse	PMID:8910344
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IGI	MGI:MGI:87894	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IGI	MGI:MGI:87895	Mouse	PMID:8798466
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IGI	MGI:MGI:87890	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IGI	MGI:MGI:87890	Mouse	PMID:8798466
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IGI	MGI:MGI:87895	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IDA		Rat	PMID:1702709|RGD:68734
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrnd	IDA		Rat	PMID:22461452|RGD:8549758
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	chrnd	IMP	ZFIN:ZDB-GENO-980202-1045	Zfish	PMID:19270440
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	Chrnd	IDA		Rat	PMID:1702709|RGD:68734
Molecular Function	GO:0005515	protein binding	Chrnd	IPI	PR:P04760	Mouse	PMID:8798466
Molecular Function	GO:0005515	protein binding	Chrnd	IPI	PR:P09690	Mouse	PMID:8798466
Molecular Function	GO:0005515	protein binding	Chrnd	IPI	PR:P35564	Mouse	PMID:8798466
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRND	IDA		Human	PMID:11435464
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRND	IMP		Human	PMID:11435464
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnd	IPI		Mouse	MGI:MGI:6828906|PMID:8334706
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnd	IPI	PR:P04756	Mouse	PMID:8910344
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnd	IDA		Mouse	PMID:8798466
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrnd	IDA		Rat	PMID:22461452|RGD:8549758
Cellular Component	GO:0005829	cytosol	CHRND	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031594	neuromuscular junction	CHRND	IDA		Human	PMID:11435464
Cellular Component	GO:0031594	neuromuscular junction	CHRND	IMP		Human	PMID:11435464
Cellular Component	GO:0031594	neuromuscular junction	Chrnd	IDA		Mouse	PMID:4781450
Cellular Component	GO:0005654	nucleoplasm	CHRND	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CHRND	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Chrnd	IDA		Mouse	PMID:12388596
Cellular Component	GO:0005886	plasma membrane	chrnd	IDA		Zfish	PMID:15201319
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrnd	IDA		Mouse	PMID:4781450
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Chrnd	IDA		Mouse	MGI:MGI:6850201|PMID:15864502
Biological Process	GO:0006812	monoatomic cation transport	Chrnd	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0050881	musculoskeletal movement	CHRND	IMP		Human	PMID:18252226
Biological Process	GO:0030239	myofibril assembly	chrnd	IMP	ZFIN:ZDB-GENO-060216-1	Zfish	PMID:16245342
Biological Process	GO:0042391	regulation of membrane potential	Chrnd	IGI	MGI:MGI:87890	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnd	IGI	MGI:MGI:87894	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnd	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnd	IGI	MGI:MGI:87890	Mouse	PMID:8798466
Biological Process	GO:0042391	regulation of membrane potential	Chrnd	IGI	MGI:MGI:87895	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrnd	IGI	MGI:MGI:87895	Mouse	PMID:8798466
Biological Process	GO:0003009	skeletal muscle contraction	Chrnd	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0048630	skeletal muscle tissue growth	CHRND	IMP		Human	PMID:18252226

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern