Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHRNE
  • Mouse genes Chrne
  • Rat genes Chrne
  • Zfish genes chrne
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chrne

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015464	acetylcholine receptor activity	chrne	IDA		Zfish	PMID:22580045
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrne	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrne	IGI	MGI:MGI:87890	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrne	IGI	MGI:MGI:87893	Mouse	PMID:2383398
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	Chrne	IDA		Rat	PMID:22461452|RGD:8549758
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNE	IDA		Human	PMID:7531341
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNE	IMP		Human	PMID:7531341
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrne	IPI		Mouse	MGI:MGI:6828906|PMID:8334706
Cellular Component	GO:0005892	acetylcholine-gated channel complex	Chrne	IDA		Rat	PMID:22461452|RGD:8549758
Cellular Component	GO:0005892	acetylcholine-gated channel complex	chrne	IDA		Zfish	PMID:22580045
Cellular Component	GO:0031594	neuromuscular junction	CHRNE	IDA		Human	PMID:7531341
Cellular Component	GO:0031594	neuromuscular junction	CHRNE	IMP		Human	PMID:7531341
Cellular Component	GO:0031594	neuromuscular junction	Chrne	IDA		Mouse	PMID:4781450
Cellular Component	GO:0031594	neuromuscular junction	Chrne	IDA		Mouse	PMID:12832540
Cellular Component	GO:0045211	postsynaptic membrane	Chrne	IDA		Mouse	PMID:15883046
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrne	IDA		Mouse	PMID:4781450
Cellular Component	GO:0099634	postsynaptic specialization membrane	Chrne	IDA		Mouse	PMID:12832540
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Chrne	IDA		Mouse	MGI:MGI:6850201|PMID:15864502
Biological Process	GO:1905145	cellular response to acetylcholine	chrne	IGI	ZFIN:ZDB-GENO-210810-10	Zfish	PMID:32284992
Biological Process	GO:0006812	monoatomic cation transport	Chrne	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0042391	regulation of membrane potential	Chrne	IGI	MGI:MGI:87885	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrne	IGI	MGI:MGI:87893	Mouse	PMID:2383398
Biological Process	GO:0042391	regulation of membrane potential	Chrne	IGI	MGI:MGI:87890	Mouse	PMID:2383398
Biological Process	GO:0003009	skeletal muscle contraction	Chrne	IDA		Rat	PMID:22461452|RGD:8549758
Biological Process	GO:0007271	synaptic transmission, cholinergic	chrne	IDA		Zfish	PMID:21844221

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern