Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CIB1
  • Mouse genes Cib1
  • Rat genes Cib1
  • Zfish genes cib1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cib1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	CIB1	IMP		Human	PMID:15475008
Molecular Function	GO:0008427	calcium-dependent protein kinase inhibitor activity	CIB1	IMP		Human	PMID:20473878
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P49810	Human	PMID:10366599
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:O95071	Human	PMID:12011095
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P09912	Human	PMID:15685448
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:O00401	Human	PMID:16582881
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q99683	Human	PMID:19805025
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q9NYA1	Human	PMID:19854831
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P63098	Human	PMID:20639889
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q63810-1	Human	PMID:20639889
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q63810-2	Human	PMID:20639889
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q9H4B4	Human	PMID:20951827
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q93045	Human	PMID:21215777
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q9H4B4	Human	PMID:21264284
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P08514	Human	PMID:22779914
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P06756	Human	PMID:24011356
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P08648	Human	PMID:24011356
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q7Z403|UniProtKB:Q8IU68	Human	PMID:30068544
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:O00746	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:O60422	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P04066	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P10092	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P23759-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P26842	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P40199	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P48449	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q04637-9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q3KNT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q6UXG2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q6ZSB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q7RTT5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q8NEA6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q9H7N4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P05362	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CIB1	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cib1	IPI	UniProtKB:Q63810-1|UniProtKB:Q63810-2	Mouse	MGI:MGI:4821678|PMID:20639889
Molecular Function	GO:0005515	protein binding	Cib1	IPI	RGD:620760	Rat	PMID:10523297|RGD:61555
Molecular Function	GO:0005515	protein binding	Cib1	IPI	UniProtKB:Q9R011	Rat	PMID:10523297|RGD:61555
Molecular Function	GO:0005515	protein binding	Cib1	IPI	UniProtKB:Q9R012	Rat	PMID:10523297|RGD:61555
Molecular Function	GO:0019901	protein kinase binding	Cib1	IPI	RGD:62039	Rat	PMID:10523297|RGD:61555
Molecular Function	GO:0019901	protein kinase binding	Cib1	IPI	RGD:620760	Rat	PMID:10523297|RGD:61555
Molecular Function	GO:0030291	protein serine/threonine kinase inhibitor activity	CIB1	IDA		Human	PMID:20473878
Molecular Function	GO:0043495	protein-membrane adaptor activity	CIB1	IGI	UniProtKB:Q9Z0F4	Human	PMID:20639889
Molecular Function	GO:0043495	protein-membrane adaptor activity	Cib1	IMP		Mouse	MGI:MGI:4821678|PMID:20639889
Molecular Function	GO:0031267	small GTPase binding	CIB1	IPI	UniProtKB:P60763	Human	PMID:11756406
Molecular Function	GO:0044325	transmembrane transporter binding	Cib1	IPI	UniProtKB:Q01815	Mouse	MGI:MGI:4821678|PMID:20639889
Cellular Component	GO:0030424	axon	Cib1	IDA		Rat	PMID:16257512|RGD:10401856
Cellular Component	GO:0071944	cell periphery	CIB1	IDA		Human	PMID:11756406
Cellular Component	GO:0071944	cell periphery	CIB1	IDA		Human	PMID:20951827
Cellular Component	GO:0005813	centrosome	CIB1	IDA		Human	PMID:20951827
Cellular Component	GO:0005737	cytoplasm	CIB1	IMP		Human	PMID:10366599
Cellular Component	GO:0005737	cytoplasm	CIB1	IDA		Human	PMID:11756406
Cellular Component	GO:0005737	cytoplasm	CIB1	IDA		Human	PMID:19854831
Cellular Component	GO:0005737	cytoplasm	CIB1	IDA		Human	PMID:20639889
Cellular Component	GO:0005737	cytoplasm	CIB1	IDA		Human	PMID:21215777
Cellular Component	GO:0005737	cytoplasm	Cib1	IMP		Mouse	MGI:MGI:3687725|PMID:10366599
Cellular Component	GO:0005737	cytoplasm	Cib1	IDA		Mouse	MGI:MGI:4821678|PMID:20639889
Cellular Component	GO:0005737	cytoplasm	Cib1	IDA		Rat	PMID:10523297|RGD:61555
Cellular Component	GO:0030425	dendrite	Cib1	IDA		Rat	PMID:10523297|RGD:61555
Cellular Component	GO:0005783	endoplasmic reticulum	CIB1	IMP		Human	PMID:10366599
Cellular Component	GO:0070062	extracellular exosome	CIB1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CIB1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CIB1	HDA		Human	PMID:23533145
Cellular Component	GO:0032433	filopodium tip	CIB1	IDA		Human	PMID:20951827
Cellular Component	GO:0030426	growth cone	CIB1	IDA		Human	PMID:21215777
Cellular Component	GO:0030027	lamellipodium	CIB1	IDA		Human	PMID:21215777
Cellular Component	GO:0016020	membrane	CIB1	IDA		Human	PMID:10366599
Cellular Component	GO:0016020	membrane	Cib1	IDA		Mouse	MGI:MGI:3687725|PMID:10366599
Cellular Component	GO:0043005	neuron projection	CIB1	IDA		Human	PMID:21215777
Cellular Component	GO:0043025	neuronal cell body	CIB1	IDA		Human	PMID:21215777
Cellular Component	GO:0043025	neuronal cell body	Cib1	IDA		Rat	PMID:10523297|RGD:61555
Cellular Component	GO:0005654	nucleoplasm	CIB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CIB1	IMP		Human	PMID:10366599
Cellular Component	GO:0005634	nucleus	CIB1	IDA		Human	PMID:11756406
Cellular Component	GO:0005634	nucleus	CIB1	IDA		Human	PMID:30068544
Cellular Component	GO:0005634	nucleus	Cib1	IDA		Rat	PMID:10523297|RGD:61555
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CIB1	IDA		Human	PMID:11756406
Cellular Component	GO:0005886	plasma membrane	CIB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CIB1	IDA		Human	PMID:19854831
Cellular Component	GO:0005886	plasma membrane	CIB1	IDA		Human	PMID:20473878
Cellular Component	GO:0042383	sarcolemma	CIB1	IDA		Human	PMID:20639889
Cellular Component	GO:0042383	sarcolemma	Cib1	IDA		Mouse	MGI:MGI:4821678|PMID:20639889
Cellular Component	GO:0031982	vesicle	CIB1	HDA		Human	PMID:19190083
Biological Process	GO:0006915	apoptotic process	CIB1	IMP		Human	PMID:10366599
Biological Process	GO:0071363	cellular response to growth factor stimulus	Cib1	IDA		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0071363	cellular response to growth factor stimulus	Cib1	IDA		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	CIB1	IDA		Human	PMID:21215777
Biological Process	GO:0071356	cellular response to tumor necrosis factor	CIB1	IMP		Human	PMID:19854831
Biological Process	GO:0031122	cytoplasmic microtubule organization	CIB1	IMP		Human	PMID:20951827
Biological Process	GO:0006974	DNA damage response	CIB1	IDA		Human	PMID:12011095
Biological Process	GO:0007113	endomitotic cell cycle	CIB1	IDA		Human	PMID:21264284
Biological Process	GO:0043066	negative regulation of apoptotic process	CIB1	IMP		Human	PMID:19854831
Biological Process	GO:0043066	negative regulation of apoptotic process	Cib1	IMP		Mouse	MGI:MGI:3689659|PMID:16982698
Biological Process	GO:0008285	negative regulation of cell population proliferation	CIB1	IMP		Human	PMID:21264284
Biological Process	GO:0045653	negative regulation of megakaryocyte differentiation	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	CIB1	IDA		Human	PMID:21215777
Biological Process	GO:0010977	negative regulation of neuron projection development	CIB1	IDA		Human	PMID:21215777
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:0030220	platelet formation	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	CIB1	IDA		Human	PMID:20639889
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	Cib1	IMP		Mouse	MGI:MGI:4821678|PMID:20639889
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	Cib1	IMP		Rat	PMID:20639889|RGD:8554486
Biological Process	GO:0043085	positive regulation of catalytic activity	Cib1	IMP		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	CIB1	IDA		Human	PMID:11756406
Biological Process	GO:0030307	positive regulation of cell growth	Cib1	IMP		Mouse	MGI:MGI:3689659|PMID:16982698
Biological Process	GO:0030335	positive regulation of cell migration	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	Cib1	IMP		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0008284	positive regulation of cell population proliferation	Cib1	IMP		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Cib1	IMP		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:2000256	positive regulation of male germ cell proliferation	Cib1	IMP		Mouse	MGI:MGI:3689659|PMID:16982698
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	CIB1	IMP		Human	PMID:19854831
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	CIB1	IGI	UniProtKB:Q9Z0F4	Human	PMID:20639889
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	Cib1	IMP		Mouse	MGI:MGI:4821678|PMID:20639889
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Cib1	IMP		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	Cib1	IMP		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	CIB1	IMP		Human	PMID:19854831
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	CIB1	IDA		Human	PMID:11756406
Biological Process	GO:0051302	regulation of cell division	CIB1	IMP		Human	PMID:20951827
Biological Process	GO:0042127	regulation of cell population proliferation	CIB1	IMP		Human	PMID:20951827
Biological Process	GO:0002931	response to ischemia	Cib1	IDA		Mouse	MGI:MGI:3818804|PMID:17975111
Biological Process	GO:0007286	spermatid development	Cib1	IMP		Mouse	MGI:MGI:3689659|PMID:16982698
Biological Process	GO:0038163	thrombopoietin-mediated signaling pathway	Cib1	IMP		Mouse	MGI:MGI:5314162|PMID:22128142

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern