Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CIC
  • Mouse genes Cic
  • Rat genes Cic
  • Zfish genes cica,cicb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cic

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Cic	IDA		Mouse	PMID:20628574
Molecular Function	GO:0003682	chromatin binding	Cic	IDA		Mouse	PMID:22014525
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:Q9HC77	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:P54253	Human	PMID:18337722
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:P54253	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:Q08379	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CIC	IPI	UniProtKB:Q99816	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Cic	IPI	UniProtKB:P0C7T6|UniProtKB:P54254	Mouse	MGI:MGI:5888926|PMID:28288114
Molecular Function	GO:0005515	protein binding	Cic	IPI	PR:P0C7T6	Mouse	PMID:20628574
Molecular Function	GO:0005515	protein binding	Cic	IPI	PR:P54254	Mouse	PMID:18337722
Molecular Function	GO:0005515	protein binding	Cic	IPI	PR:P54254	Mouse	PMID:20628574
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CIC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CIC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Cic	IDA		Mouse	PMID:18337722
Biological Process	GO:0007420	brain development	Cic	IMP		Mouse	MGI:MGI:5888926|PMID:28288114
Biological Process	GO:0007612	learning	Cic	IMP		Mouse	MGI:MGI:5888926|PMID:28288114
Biological Process	GO:0048286	lung alveolus development	Cic	IGI	MGI:MGI:3694797	Mouse	PMID:22014525
Biological Process	GO:0048286	lung alveolus development	Cic	IGI	MGI:MGI:104783	Mouse	PMID:22014525
Biological Process	GO:0048286	lung alveolus development	Cic	IMP	MGI:MGI:4125985	Mouse	PMID:22014525
Biological Process	GO:0007613	memory	Cic	IMP		Mouse	MGI:MGI:5888926|PMID:28288114
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cic	IMP		Mouse	MGI:MGI:5888926|PMID:28288114
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cic	IGI	MGI:MGI:104783	Mouse	PMID:22014525
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cic	IGI	MGI:MGI:3694797	Mouse	PMID:20628574
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cic	IGI	MGI:MGI:3694797	Mouse	PMID:22014525
Biological Process	GO:0060319	primitive erythrocyte differentiation	cicb	IMP	ZFIN:ZDB-MRPHLNO-141211-16	Zfish	PMID:24240475
Biological Process	GO:0035176	social behavior	Cic	IMP		Mouse	MGI:MGI:5888926|PMID:28288114
Biological Process	GO:0006366	transcription by RNA polymerase II	Cic	IGI	MGI:MGI:104783	Mouse	PMID:22014525
Biological Process	GO:0006366	transcription by RNA polymerase II	Cic	IGI	MGI:MGI:3694797	Mouse	PMID:22014525

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern