Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CIITA
  • Mouse genes Ciita
  • Rat genes Ciita
  • Zfish genes ciita
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ciita

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	CIITA	IPI	UniProtKB:Q16594	Human	PMID:9171108
Molecular Function	GO:0005515	protein binding	CIITA	IPI	UniProtKB:P48382	Human	PMID:10938133
Molecular Function	GO:0005515	protein binding	CIITA	IPI	UniProtKB:Q2QGD7	Human	PMID:16600381
Molecular Function	GO:0005515	protein binding	CIITA	IPI	UniProtKB:P98168	Human	PMID:17493635
Molecular Function	GO:0005515	protein binding	CIITA	IPI	UniProtKB:Q2QGD7	Human	PMID:17493635
Molecular Function	GO:0005515	protein binding	CIITA	IPI	UniProtKB:Q96EB6	Human	PMID:21890893
Molecular Function	GO:0005515	protein binding	CIITA	IPI	UniProtKB:P29590-2	Human	PMID:23007646
Molecular Function	GO:0005515	protein binding	Ciita	IPI	UniProtKB:Q07279	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0044877	protein-containing complex binding	CIITA	IDA		Human	PMID:17493635
Molecular Function	GO:0000976	transcription cis-regulatory region binding	CIITA	IDA		Human	PMID:19041327
Cellular Component	GO:0009986	cell surface	Ciita	IDA		Rat	PMID:23524893|RGD:7242890
Cellular Component	GO:0005829	cytosol	CIITA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CIITA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016605	PML body	CIITA	IDA		Human	PMID:23007646
Biological Process	GO:0007568	aging	Ciita	IEP		Rat	PMID:15890435|RGD:2313439
Biological Process	GO:0071257	cellular response to electrical stimulus	Ciita	IEP		Rat	PMID:10051633|RGD:7242894
Biological Process	GO:0071360	cellular response to exogenous dsRNA	Ciita	IEP		Rat	PMID:10051633|RGD:7242894
Biological Process	GO:0071346	cellular response to type II interferon	Ciita	IEP		Rat	PMID:11071855|RGD:632488
Biological Process	GO:0006954	inflammatory response	Ciita	IEP		Rat	PMID:15821736|RGD:1358146
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CIITA	IDA		Human	PMID:19041327
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ciita	IMP	MGI:MGI:1857456	Mouse	PMID:15100295
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CIITA	IMP		Human	PMID:19041327
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ciita	IDA		Rat	PMID:11071855|RGD:632488
Biological Process	GO:0046597	negative regulation of viral entry into host cell	CIITA	IDA		Human	PMID:32855215
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CIITA	IDA		Human	PMID:19041327
Biological Process	GO:0045345	positive regulation of MHC class I biosynthetic process	CIITA	IDA		Human	PMID:20639463
Biological Process	GO:0045348	positive regulation of MHC class II biosynthetic process	Ciita	IDA		Rat	PMID:11071855|RGD:632488
Biological Process	GO:0045348	positive regulation of MHC class II biosynthetic process	Ciita	IEP		Rat	PMID:11477547|RGD:632487
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CIITA	IDA		Human	PMID:20639463
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CIITA	IDA		Human	PMID:32855215
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CIITA	IMP		Human	PMID:9171108
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ciita	IDA		Mouse	MGI:MGI:6478071|PMID:32855215
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ciita	IDA		Rat	PMID:11071855|RGD:632488
Biological Process	GO:0046677	response to antibiotic	CIITA	IDA		Human	PMID:107465
Biological Process	GO:0034341	response to type II interferon	CIITA	IDA		Human	PMID:19041327
Biological Process	GO:0034341	response to type II interferon	CIITA	IDA		Human	PMID:32855215
Biological Process	GO:0034341	response to type II interferon	Ciita	IDA		Mouse	MGI:MGI:6478071|PMID:32855215
Biological Process	GO:0034341	response to type II interferon	Ciita	IDA		Mouse	PMID:16280321

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern