Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CILK1
  • Mouse genes Cilk1
  • Rat genes Cilk1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cilk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	CILK1	IDA		Human	PMID:10699974
Molecular Function	GO:0005524	ATP binding	Cilk1	IDA		Rat	PMID:8570168|RGD:70769
Molecular Function	GO:0000287	magnesium ion binding	CILK1	IDA		Human	PMID:10699974
Molecular Function	GO:0005515	protein binding	CILK1	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	CILK1	IPI	UniProtKB:Q9NRG4	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	CILK1	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CILK1	IPI	UniProtKB:Q9NRG4	Human	PMID:32707033
Molecular Function	GO:0004672	protein kinase activity	CILK1	IDA		Human	PMID:19185282
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CILK1	IDA		Human	PMID:10699974
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cilk1	IDA		Mouse	PMID:10699974
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cilk1	IDA		Rat	PMID:8570168|RGD:70769
Cellular Component	GO:0036064	ciliary basal body	Cilk1	IDA		Mouse	MGI:MGI:5575814|PMID:24853502
Cellular Component	GO:0097546	ciliary base	Cilk1	IDA		Mouse	MGI:MGI:5787768|PMID:25243405
Cellular Component	GO:0097542	ciliary tip	CILK1	IMP		Human	PMID:24797473
Cellular Component	GO:0097542	ciliary tip	Cilk1	IMP		Mouse	MGI:MGI:5575827|PMID:24797473
Cellular Component	GO:0005929	cilium	Cilk1	IDA		Mouse	MGI:MGI:5787768|PMID:25243405
Cellular Component	GO:0005737	cytoplasm	Cilk1	IDA		Rat	PMID:8570168|RGD:70769
Cellular Component	GO:0001650	fibrillar center	CILK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CILK1	IDA		Human	PMID:19185282
Cellular Component	GO:0005634	nucleus	Cilk1	IDA		Mouse	MGI:MGI:5787768|PMID:25243405
Biological Process	GO:0060271	cilium assembly	CILK1	IMP		Human	PMID:24797473
Biological Process	GO:0060271	cilium assembly	Cilk1	IMP		Mouse	MGI:MGI:5575827|PMID:24797473
Biological Process	GO:0035556	intracellular signal transduction	CILK1	IDA		Human	PMID:10699974
Biological Process	GO:0035556	intracellular signal transduction	Cilk1	IDA		Rat	PMID:8570168|RGD:70769
Biological Process	GO:0035720	intraciliary anterograde transport	Cilk1	IMP		Mouse	MGI:MGI:5787768|PMID:25243405
Biological Process	GO:0035721	intraciliary retrograde transport	Cilk1	IMP		Mouse	MGI:MGI:5787768|PMID:25243405
Biological Process	GO:0042073	intraciliary transport	Cilk1	IMP		Mouse	MGI:MGI:5575827|PMID:24797473
Biological Process	GO:0006468	protein phosphorylation	CILK1	IDA		Human	PMID:10699974
Biological Process	GO:0006468	protein phosphorylation	Cilk1	IDA		Mouse	MGI:MGI:5575827|PMID:24797473
Biological Process	GO:0006468	protein phosphorylation	Cilk1	IDA		Rat	PMID:8570168|RGD:70769

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern