Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CISD2
  • Mouse genes Cisd2
  • Rat genes Cisd2
  • Zfish genes cisd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cisd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051537	2 iron, 2 sulfur cluster binding	CISD2	IDA		Human	PMID:19580816
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P10415	Human	PMID:20010695
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q07817	Human	PMID:20010695
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q14643	Human	PMID:20010695
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:B2RUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O14523	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O14735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O15155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O15400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O60883	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O75379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P01350	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P30301	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P42857	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P43628	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P46695	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P49638	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P50402	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P78369	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q14656	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q5VZY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q6UX34	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q7Z4F1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q86UF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q86Y82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8N0U8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8N2M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8N3T1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8N6R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8N912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8WVV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8WVX3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8WWG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8WWT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8WZA1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q969S0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96D05-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96GM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96PS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q96T60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9BQE5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9BTV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9BU79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9BXR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9C0I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9H115	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9HCP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9NVV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9NWW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9UHJ9-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9Y2E5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:P26436	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8TAB5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q8WXF7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q99932-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CISD2	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	CISD2	IDA		Human	PMID:19580816
Molecular Function	GO:0003723	RNA binding	CISD2	HDA		Human	PMID:22658674
Cellular Component	GO:0005783	endoplasmic reticulum	CISD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	CISD2	IDA		Human	PMID:20010695
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Cisd2	IDA		Mouse	MGI:MGI:3845412|PMID:19451219
Cellular Component	GO:0016020	membrane	CISD2	HDA		Human	PMID:19946888
Cellular Component	GO:0005741	mitochondrial outer membrane	Cisd2	IDA		Mouse	MGI:MGI:3845412|PMID:19451219
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	CISD2	IDA		Human	PMID:17376863
Cellular Component	GO:0032991	protein-containing complex	CISD2	IDA		Human	GO_REF:0000054
Biological Process	GO:0000422	autophagy of mitochondrion	Cisd2	IMP		Mouse	MGI:MGI:3845412|PMID:19451219
Biological Process	GO:0010506	regulation of autophagy	CISD2	IMP		Human	PMID:20010695

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern