Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CIT
  • Mouse genes Cit
  • Rat genes Cit
  • Zfish genes cita
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cit

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	CIT	IDA		Human	PMID:17474715
Molecular Function	GO:0005515	protein binding	CIT	IPI	UniProtKB:Q15058	Human	PMID:16431929
Molecular Function	GO:0005515	protein binding	Cit	IPI	PR:Q62159	Mouse	PMID:8543060
Molecular Function	GO:0005515	protein binding	Cit	IPI	MGI:MGI:1276539	Mouse	PMID:17143286
Molecular Function	GO:0005515	protein binding	Cit	IPI	PR:P63001	Mouse	PMID:8543060
Molecular Function	GO:0005515	protein binding	Cit	IPI	UniProtKB:P53804	Mouse	PMID:17143286
Molecular Function	GO:0005515	protein binding	Cit	IPI	PR:Q9QUI0	Mouse	PMID:8543060
Molecular Function	GO:0005515	protein binding	Cit	IPI	PR:P62746	Mouse	PMID:8543060
Molecular Function	GO:0019901	protein kinase binding	CIT	IPI	UniProtKB:Q9NRM7	Human	PMID:30865227
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cit	IDA		Mouse	PMID:9792683
Molecular Function	GO:0030291	protein serine/threonine kinase inhibitor activity	CIT	IDA		Human	PMID:30865227
Molecular Function	GO:0097110	scaffold protein binding	CIT	IDA		Human	PMID:17474715
Molecular Function	GO:0001223	transcription coactivator binding	CIT	IPI	UniProtKB:P46937	Human	PMID:30865227
Cellular Component	GO:0015629	actin cytoskeleton	Cit	IDA		Mouse	PMID:9792683
Cellular Component	GO:0032154	cleavage furrow	Cit	IDA		Rat	PMID:11932363|RGD:13204832
Cellular Component	GO:0005737	cytoplasm	Cit	IDA		Mouse	PMID:12781320
Cellular Component	GO:0005829	cytosol	CIT	IDA		Human	PMID:30865227
Cellular Component	GO:0005829	cytosol	Cit	IDA		Rat	PMID:12411428|RGD:628497
Cellular Component	GO:0031985	Golgi cisterna	Cit	IDA		Rat	PMID:14595335|RGD:1358646
Cellular Component	GO:0016020	membrane	CIT	HDA		Human	PMID:19946888
Cellular Component	GO:0030496	midbody	Cit	IDA		Rat	PMID:17534152|RGD:13442487
Cellular Component	GO:0043025	neuronal cell body	Cit	IDA		Rat	PMID:14595335|RGD:1358646
Cellular Component	GO:0005634	nucleus	Cit	IDA		Rat	PMID:12411428|RGD:628497
Cellular Component	GO:0005886	plasma membrane	Cit	IDA		Rat	PMID:14595335|RGD:1358646
Cellular Component	GO:0001726	ruffle	Cit	IDA		Mouse	PMID:12781320
Cellular Component	GO:0005773	vacuole	Cit	IDA		Mouse	PMID:17488780
Biological Process	GO:0000910	cytokinesis	Cit	IMP	MGI:MGI:2447844	Mouse	PMID:11086988
Biological Process	GO:0000910	cytokinesis	Cit	IMP	MGI:MGI:2447844	Mouse	PMID:12432070
Biological Process	GO:0016358	dendrite development	Cit	IMP	MGI:MGI:2447844	Mouse	PMID:12781320
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	Cit	IMP		Rat	PMID:12411428|RGD:628497
Biological Process	GO:0048699	generation of neurons	Cit	IDA		Mouse	MGI:MGI:2181325|PMID:11086988
Biological Process	GO:0007030	Golgi organization	Cit	IMP		Rat	PMID:14595335|RGD:1358646
Biological Process	GO:0001889	liver development	Cit	IEP		Rat	PMID:12411428|RGD:628497
Biological Process	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	Cit	IMP	MGI:MGI:2447844	Mouse	PMID:12764032
Biological Process	GO:0000278	mitotic cell cycle	Cit	IDA		Mouse	MGI:MGI:2181325|PMID:11086988
Biological Process	GO:0000281	mitotic cytokinesis	CIT	IMP		Human	PMID:16236794
Biological Process	GO:0000281	mitotic cytokinesis	CIT	IMP		Human	PMID:27453578
Biological Process	GO:0000070	mitotic sister chromatid segregation	Cit	IMP	MGI:MGI:2447844	Mouse	PMID:12764032
Biological Process	GO:0050774	negative regulation of dendrite morphogenesis	Cit	IDA		Mouse	PMID:12781320
Biological Process	GO:0035331	negative regulation of hippo signaling	CIT	IMP		Human	PMID:30865227
Biological Process	GO:0051402	neuron apoptotic process	CIT	IMP		Human	PMID:27453578
Biological Process	GO:0032467	positive regulation of cytokinesis	CIT	IMP		Human	PMID:16431929
Biological Process	GO:0008064	regulation of actin polymerization or depolymerization	Cit	IDA		Rat	PMID:14595335|RGD:1358646
Biological Process	GO:0007283	spermatogenesis	Cit	IMP	MGI:MGI:2447844	Mouse	PMID:12432070

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern