Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLASP1
  • Mouse genes Clasp1
  • Rat genes Clasp1
  • Zfish genes clasp1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clasp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002162	dystroglycan binding	CLASP1	IPI	UniProtKB:Q14118	Human	PMID:23940118
Molecular Function	GO:0043515	kinetochore binding	CLASP1	IMP		Human	PMID:12837247
Molecular Function	GO:0008017	microtubule binding	CLASP1	IDA		Human	PMID:11290329
Molecular Function	GO:0008017	microtubule binding	CLASP1	IMP		Human	PMID:12837247
Molecular Function	GO:0008017	microtubule binding	Clasp1	IDA		Mouse	PMID:11290329
Molecular Function	GO:0051010	microtubule plus-end binding	CLASP1	IDA		Human	PMID:12837247
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:O55156	Human	PMID:11290329
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:Q9JK25	Human	PMID:11290329
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:Q15691	Human	PMID:15631994
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:P60709	Human	PMID:17342765
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:Q8IWJ2	Human	PMID:17543864
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:O60333	Human	PMID:20852589
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:Q96R06	Human	PMID:20852589
Molecular Function	GO:0005515	protein binding	CLASP1	IPI	UniProtKB:Q9P270	Human	PMID:21646404
Molecular Function	GO:0005515	protein binding	Clasp1	IPI	UniProtKB:Q9QXZ0	Mouse	MGI:MGI:3828223|PMID:18854161
Molecular Function	GO:0005515	protein binding	Clasp1	IPI	UniProtKB:Q3U5C7	Mouse	PMID:27378169
Molecular Function	GO:0005515	protein binding	Clasp1	IPI	PR:Q9Z0H8	Mouse	PMID:11290329
Molecular Function	GO:0005515	protein binding	Clasp1	IPI	MGI:MGI:1928401	Mouse	PMID:11290329
Cellular Component	GO:0045180	basal cortex	CLASP1	IDA		Human	PMID:23940118
Cellular Component	GO:0005938	cell cortex	CLASP1	IDA		Human	PMID:17113391
Cellular Component	GO:0031592	centrosomal corona	CLASP1	IDA		Human	PMID:16914514
Cellular Component	GO:0005813	centrosome	CLASP1	IDA		Human	PMID:12837247
Cellular Component	GO:0005813	centrosome	CLASP1	IDA		Human	PMID:15631994
Cellular Component	GO:0005813	centrosome	CLASP1	IDA		Human	PMID:21399614
Cellular Component	GO:0030981	cortical microtubule cytoskeleton	CLASP1	IDA		Human	PMID:12837247
Cellular Component	GO:0005737	cytoplasm	Clasp1	IDA		Rat	PMID:28351621|RGD:27096077
Cellular Component	GO:0005881	cytoplasmic microtubule	CLASP1	IDA		Human	PMID:11290329
Cellular Component	GO:0005925	focal adhesion	CLASP1	IDA		Human	PMID:24859005
Cellular Component	GO:0005794	Golgi apparatus	CLASP1	IDA		Human	PMID:15631994
Cellular Component	GO:0000776	kinetochore	CLASP1	IDA		Human	PMID:12837247
Cellular Component	GO:0000776	kinetochore	Clasp1	IDA		Rat	PMID:28351621|RGD:27096077
Cellular Component	GO:0016020	membrane	CLASP1	HDA		Human	PMID:19946888
Cellular Component	GO:0015630	microtubule cytoskeleton	Clasp1	IDA		Mouse	PMID:11290329
Cellular Component	GO:0005876	spindle microtubule	CLASP1	IDA		Human	PMID:12837247
Biological Process	GO:0030953	astral microtubule organization	CLASP1	IMP		Human	PMID:23783028
Biological Process	GO:0051301	cell division	CLASP1	IDA		Human	PMID:21822276
Biological Process	GO:0016477	cell migration	Clasp1	IGI	MGI:MGI:1916034	Mouse	PMID:27378169
Biological Process	GO:0030010	establishment of cell polarity	Clasp1	IGI	MGI:MGI:1916034	Mouse	PMID:27378169
Biological Process	GO:0040001	establishment of mitotic spindle localization	CLASP1	IMP		Human	PMID:23783028
Biological Process	GO:0051294	establishment of spindle orientation	CLASP1	IDA		Human	PMID:21822276
Biological Process	GO:0051294	establishment of spindle orientation	CLASP1	IGI	UniProtKB:P27816	Human	PMID:21822276
Biological Process	GO:0051294	establishment of spindle orientation	CLASP1	IMP		Human	PMID:21822276
Biological Process	GO:0010458	exit from mitosis	CLASP1	IMP		Human	PMID:16866869
Biological Process	GO:0007030	Golgi organization	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0034453	microtubule anchoring	CLASP1	IMP		Human	PMID:17543864
Biological Process	GO:0034453	microtubule anchoring	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0001578	microtubule bundle formation	CLASP1	IMP		Human	PMID:12837247
Biological Process	GO:0000226	microtubule cytoskeleton organization	CLASP1	IGI	UniProtKB:O75122	Human	PMID:15631994
Biological Process	GO:0000226	microtubule cytoskeleton organization	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0007020	microtubule nucleation	CLASP1	IMP		Human	PMID:17543864
Biological Process	GO:0031023	microtubule organizing center organization	CLASP1	IMP		Human	PMID:17543864
Biological Process	GO:0007052	mitotic spindle organization	CLASP1	IMP		Human	PMID:16866869
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	CLASP1	IGI	UniProtKB:O75122	Human	PMID:15631994
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	CLASP1	IMP		Human	PMID:16866869
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Clasp1	IDA		Mouse	PMID:11290329
Biological Process	GO:0031111	negative regulation of microtubule polymerization or depolymerization	CLASP1	IMP		Human	PMID:12837247
Biological Process	GO:0051497	negative regulation of stress fiber assembly	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:1903690	negative regulation of wound healing, spreading of epidermal cells	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP1	IGI	UniProtKB:Q86SQ0|UniProtKB:Q86UU1	Human	PMID:23940118
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP1	IMP		Human	PMID:23940118
Biological Process	GO:0010634	positive regulation of epithelial cell migration	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0045921	positive regulation of exocytosis	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	CLASP1	IMP		Human	PMID:23940118
Biological Process	GO:0051893	regulation of focal adhesion assembly	CLASP1	IMP		Human	PMID:24859005
Biological Process	GO:0010470	regulation of gastrulation	CLASP1	IMP		Human	PMID:23940118
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	CLASP1	IGI	UniProtKB:Q86SQ0|UniProtKB:Q86UU1	Human	PMID:23940118
Biological Process	GO:0006903	vesicle targeting	CLASP1	IMP		Human	PMID:24859005

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern