Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLCN7
  • Mouse genes Clcn7
  • Rat genes Clcn7
  • Zfish genes clcn7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clcn7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:O00258	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:P35372-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q6P5T0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q8N2U9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q8TB36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q9UGI6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q9Y5Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q53GS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLCN7	IPI	UniProtKB:Q86WC4	Human	PMID:32851177
Molecular Function	GO:0005515	protein binding	Clcn7	IPI	UniProtKB:Q8BGT0	Mouse	MGI:MGI:3619836|PMID:16525474
Cellular Component	GO:0034707	chloride channel complex	CLCN7	IPI		Human	PMID:32851177
Cellular Component	GO:0031410	cytoplasmic vesicle	Clcn7	IDA		Rat	PMID:12637509|RGD:1600863
Cellular Component	GO:0005765	lysosomal membrane	CLCN7	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	clcn7	IMP		Zfish	PMID:32061435|ZFIN:ZDB-PUB-200221-2
Cellular Component	GO:0016020	membrane	CLCN7	HDA		Human	PMID:19946888
Biological Process	GO:1905146	lysosomal protein catabolic process	clcn7	IMP	ZFIN:ZDB-FISH-210602-5	Zfish	ZFIN:ZDB-PUB-200221-2
Biological Process	GO:0009268	response to pH	Clcn7	IDA		Rat	PMID:11846422|RGD:1600865
Biological Process	GO:0030321	transepithelial chloride transport	CLCN7	IDA		Human	PMID:32851177

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern