Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLDN12
  • Mouse genes Cldn12
  • Rat genes Cldn12
  • Zfish genes cldn12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cldn12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLDN12	IPI	UniProtKB:Q16625	Human	PMID:20375010
Molecular Function	GO:0005515	protein binding	CLDN12	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Cellular Component	GO:0071944	cell periphery	Cldn12	IDA		Mouse	PMID:19416898
Cellular Component	GO:0016328	lateral plasma membrane	Cldn12	IDA		Mouse	PMID:16651389
Cellular Component	GO:0005886	plasma membrane	CLDN12	IDA		Human	PMID:20375010
Cellular Component	GO:0070160	tight junction	Cldn12	IDA		Mouse	MGI:MGI:6369916|PMID:30734065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern