Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLDN6
  • Mouse genes Cldn6
  • Rat genes Cldn6
  • Zfish genes cldn29,cldn3c,cldn3d,cldnd,cldng,cldnj,cldnk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cldn6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:P60033	Human	PMID:20375010
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:Q16625	Human	PMID:20375010
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN6	IPI	UniProtKB:Q96HJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cldn6	IPI	UniProtKB:P39447|UniProtKB:Q9QXY1|UniProtKB:Q9Z0U1	Mouse	MGI:MGI:1350677|PMID:10601346
Molecular Function	GO:0001618	virus receptor activity	CLDN6	IMP		Human	PMID:20375010
Cellular Component	GO:0016327	apicolateral plasma membrane	Cldn6	IDA		Mouse	MGI:MGI:1355488|PMID:9892664
Cellular Component	GO:0005923	bicellular tight junction	Cldn6	IDA		Mouse	MGI:MGI:1355488|PMID:9892664
Cellular Component	GO:0005923	bicellular tight junction	Cldn6	IDA		Mouse	PMID:17130295
Cellular Component	GO:0005886	plasma membrane	CLDN6	IDA		Human	PMID:20375010
Cellular Component	GO:0005886	plasma membrane	Cldn6	IDA		Mouse	PMID:12060405
Cellular Component	GO:0005886	plasma membrane	Cldn6	IDA		Mouse	PMID:17130295
Biological Process	GO:0045216	cell-cell junction organization	Cldn6	IDA		Mouse	PMID:17130295
Biological Process	GO:0031101	fin regeneration	cldn3d	IMP	ZFIN:ZDB-MRPHLNO-160627-5	Zfish	PMID:26933814
Biological Process	GO:0031174	lifelong otolith mineralization	cldnj	IMP	ZFIN:ZDB-GENO-040713-5	Zfish	PMID:15925497
Biological Process	GO:0003407	neural retina development	cldn3c	IMP	ZFIN:ZDB-MRPHLNO-210702-1	Zfish	PMID:32866532
Biological Process	GO:0003407	neural retina development	cldn3c	IMP	ZFIN:ZDB-MRPHLNO-210702-2	Zfish	PMID:32866532
Biological Process	GO:0035678	neuromast hair cell morphogenesis	cldn3c	IMP	ZFIN:ZDB-GENO-230126-5	Zfish	PMID:34046408
Biological Process	GO:0035678	neuromast hair cell morphogenesis	cldn3c	IMP	ZFIN:ZDB-MRPHLNO-220318-1	Zfish	PMID:34046408
Biological Process	GO:0007605	sensory perception of sound	cldn3c	IMP	ZFIN:ZDB-MRPHLNO-220318-1	Zfish	PMID:34046408
Biological Process	GO:0060116	vestibular receptor cell morphogenesis	cldn3c	IMP	ZFIN:ZDB-MRPHLNO-220318-1	Zfish	PMID:34046408
Biological Process	GO:0060116	vestibular receptor cell morphogenesis	cldn3c	IMP	ZFIN:ZDB-GENO-230126-5	Zfish	PMID:34046408

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern