Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cldn7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CLDN7
- Mouse genes Cldn7
- Rat genes Cldn7
- Zfish genes cldn7a,cldn7b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cldn7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	Cldn7	IPI	RGD:621365	Rat	PMID:19276185\|RGD:9685062
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P16422	Human	PMID:16054130
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:A2A2V5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O14569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O15155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O43169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O43561-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O43736	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O60883	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O75396	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:O95406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P01375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P05090	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P07306	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P17152	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P21854	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P29400-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P54852	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:P56851	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q07325	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q0D2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q14162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q16617	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q2T9K0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q5BJF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q5BJH2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q6N075	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q6UX06	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q7Z2K6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q86UF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q8N112	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q8NBI2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q969E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q96IV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9BVK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9H0Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9H1C4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NV12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NV29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NVV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NWW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9NX14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9UHJ9-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9UKR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLDN7	IPI	UniProtKB:Q9Y5Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cldn7	IPI	UniProtKB:P39447\|UniProtKB:Q9QXY1\|UniProtKB:Q9Z0U1	Mouse	MGI:MGI:1350677\|PMID:10601346
Molecular Function	GO:0019904	protein domain specific binding	Cldn7	IPI	RGD:621365	Rat	PMID:19276185\|RGD:9685062
Cellular Component	GO:0016327	apicolateral plasma membrane	Cldn7	IDA		Mouse	MGI:MGI:1355488\|PMID:9892664
Cellular Component	GO:0016323	basolateral plasma membrane	Cldn7	IDA		Mouse	PMID:16651389
Cellular Component	GO:0016323	basolateral plasma membrane	Cldn7	IDA		Rat	PMID:23180307\|RGD:9685072
Cellular Component	GO:0005923	bicellular tight junction	Cldn7	IDA		Mouse	MGI:MGI:1355488\|PMID:9892664
Cellular Component	GO:0005923	bicellular tight junction	Cldn7	IDA		Mouse	PMID:22275141
Cellular Component	GO:0005923	bicellular tight junction	Cldn7	IDA		Mouse	PMID:16651389
Cellular Component	GO:0005923	bicellular tight junction	Cldn7	IDA		Mouse	PMID:23610556
Cellular Component	GO:0005923	bicellular tight junction	Cldn7	IDA		Mouse	PMID:22946046
Cellular Component	GO:0016328	lateral plasma membrane	Cldn7	IDA		Mouse	PMID:22275141
Cellular Component	GO:0016328	lateral plasma membrane	Cldn7	IDA		Rat	PMID:17853415\|RGD:9685071
Cellular Component	GO:0005886	plasma membrane	CLDN7	IDA		Human	PMID:12673207
Cellular Component	GO:0005886	plasma membrane	CLDN7	IDA		Human	PMID:20375010
Cellular Component	GO:0005886	plasma membrane	Cldn7	IDA		Mouse	PMID:16651389
Biological Process	GO:0034332	adherens junction organization	cldn7b	IMP	ZFIN:ZDB-GENO-180705-3	Zfish	PMID:28834538
Biological Process	GO:0090136	epithelial cell-cell adhesion	cldn7b	IMP	ZFIN:ZDB-GENO-180705-3	Zfish	PMID:28834538
Biological Process	GO:0060322	head development	cldn7a	IGI	ZFIN:ZDB-MRPHLNO-150213-2,ZFIN:ZDB-MRPHLNO-150213-4	Zfish	PMID:25439725
Biological Process	GO:0060322	head development	cldn7a	IMP	ZFIN:ZDB-MRPHLNO-150213-4	Zfish	PMID:25439725
Biological Process	GO:0043066	negative regulation of apoptotic process	Cldn7	IDA		Rat	PMID:19276185\|RGD:9685062
Biological Process	GO:0007162	negative regulation of cell adhesion	Cldn7	IDA		Rat	PMID:19276185\|RGD:9685062
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	Cldn7	IDA		Rat	PMID:19276185\|RGD:9685062
Biological Process	GO:0048840	otolith development	cldn7b	IMP	ZFIN:ZDB-GENO-180705-3	Zfish	PMID:28834538
Biological Process	GO:2000147	positive regulation of cell motility	Cldn7	IDA		Rat	PMID:19276185\|RGD:9685062
Biological Process	GO:0008284	positive regulation of cell population proliferation	Cldn7	IDA		Rat	PMID:19276185\|RGD:9685062
Biological Process	GO:0045471	response to ethanol	Cldn7	IEP		Rat	PMID:17889313\|RGD:11344881
Biological Process	GO:0060876	semicircular canal formation	cldn7b	IMP	ZFIN:ZDB-GENO-180705-3	Zfish	PMID:28834538
Biological Process	GO:0007605	sensory perception of sound	cldn7b	IMP	ZFIN:ZDB-GENO-180705-3	Zfish	PMID:28834538

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/03/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.