Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLEC14A
  • Mouse genes Clec14a
  • Rat genes Clec14a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clec14a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990430	extracellular matrix protein binding	CLEC14A	IDA		Human	PMID:25745997
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:P35916	Human	PMID:27991863
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:O14493	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:O14569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:O60636	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:P11836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:P27449	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:P50402	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q99735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLEC14A	IPI	UniProtKB:Q9BU79	Human	PMID:32296183
Cellular Component	GO:0062023	collagen-containing extracellular matrix	CLEC14A	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Clec14a	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0009897	external side of plasma membrane	CLEC14A	IDA		Human	PMID:25745997
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	Clec14a	IMP	MGI:MGI:5292853	Mouse	PMID:25745997
Biological Process	GO:0001946	lymphangiogenesis	Clec14a	IMP	MGI:MGI:6404416	Mouse	PMID:27991863
Biological Process	GO:0002040	sprouting angiogenesis	Clec14a	IMP	MGI:MGI:6404416	Mouse	PMID:27991863
Biological Process	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway	CLEC14A	IMP		Human	PMID:27991863
Biological Process	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway	Clec14a	IMP	MGI:6404416	Mouse	PMID:27991863
Biological Process	GO:0036325	vascular endothelial growth factor receptor-3 signaling pathway	CLEC14A	IMP		Human	PMID:27991863
Biological Process	GO:0036325	vascular endothelial growth factor receptor-3 signaling pathway	Clec14a	IMP	MGI:6404416	Mouse	PMID:27991863

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern