Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLEC16A
  • Mouse genes Clec16a
  • Rat genes Clec16a
  • Zfish genes clec16a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clec16a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Clec16a	IPI	UniProtKB:Q8BH75	Mouse	MGI:MGI:5603233|PMID:24949970
Cellular Component	GO:0005829	cytosol	CLEC16A	IDA		Human	PMID:28223137
Cellular Component	GO:0036020	endolysosome membrane	Clec16a	IDA		Mouse	PMID:24949970
Cellular Component	GO:0005794	Golgi apparatus	CLEC16A	IDA		Human	PMID:28223137
Cellular Component	GO:0031982	vesicle	CLEC16A	IDA		Human	PMID:28223137
Biological Process	GO:0009267	cellular response to starvation	CLEC16A	IMP		Human	PMID:28223137
Biological Process	GO:1901097	negative regulation of autophagosome maturation	CLEC16A	IMP		Human	PMID:28223137
Biological Process	GO:1901525	negative regulation of mitophagy	Clec16a	IMP	MGI:MGI:5648633	Mouse	PMID:24949970
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Clec16a	IMP	MGI:MGI:5648633	Mouse	PMID:24949970
Biological Process	GO:1901098	positive regulation of autophagosome maturation	Clec16a	IMP	MGI:MGI:5648633	Mouse	PMID:24949970
Biological Process	GO:1904263	positive regulation of TORC1 signaling	CLEC16A	IMP		Human	PMID:28223137
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Clec16a	IMP	MGI:MGI:5648633	Mouse	PMID:24949970

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern