Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLEC5A
  • Mouse genes Clec5a
  • Rat genes Clec5a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clec5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Clec5a	IPI	UniProtKB:Q9QUJ0	Mouse	MGI:MGI:5009374|PMID:19074552
Molecular Function	GO:0005515	protein binding	Clec5a	IPI	UniProtKB:O54885|UniProtKB:Q9QUJ0	Mouse	MGI:MGI:3839503|PMID:19251634
Molecular Function	GO:0001618	virus receptor activity	CLEC5A	IDA		Human	PMID:18496526
Molecular Function	GO:0001618	virus receptor activity	Clec5a	IDA		Mouse	MGI:MGI:5009381|PMID:18496526
Cellular Component	GO:0009986	cell surface	Clec5a	IDA		Mouse	MGI:MGI:5009374|PMID:19074552
Cellular Component	GO:0005829	cytosol	CLEC5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CLEC5A	IDA		Human	GO_REF:0000052
Biological Process	GO:0045087	innate immune response	CLEC5A	IDA		Human	PMID:18496526
Biological Process	GO:0045087	innate immune response	Clec5a	IDA		Mouse	MGI:MGI:5009374|PMID:19074552
Biological Process	GO:0030099	myeloid cell differentiation	Clec5a	IGI	MGI:MGI:1339751	Mouse	PMID:24216483
Biological Process	GO:0043066	negative regulation of apoptotic process	Clec5a	IDA		Mouse	MGI:MGI:5009374|PMID:19074552
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	Clec5a	IDA		Mouse	PMID:19074552
Biological Process	GO:0002076	osteoblast development	Clec5a	IDA		Mouse	MGI:MGI:3839503|PMID:19251634
Biological Process	GO:0001819	positive regulation of cytokine production	Clec5a	IMP		Mouse	MGI:MGI:5009381|PMID:18496526

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern