Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLEC7A
  • Mouse genes Clec7a
  • Rat genes Clec7a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clec7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001872	(1->3)-beta-D-glucan binding	CLEC7A	IDA		Human	PMID:22267217
Molecular Function	GO:0001872	(1->3)-beta-D-glucan binding	CLEC7A	IDA		Human	PMID:24721111
Molecular Function	GO:0001872	(1->3)-beta-D-glucan binding	Clec7a	IDA		Mouse	PMID:12163569
Molecular Function	GO:0001872	(1->3)-beta-D-glucan binding	Clec7a	IDA		Mouse	PMID:14698225
Molecular Function	GO:0001872	(1->3)-beta-D-glucan binding	Clec7a	IDA		Mouse	PMID:14707091
Molecular Function	GO:0001874	(1->3)-beta-D-glucan immune receptor activity	Clec7a	IDA		Mouse	PMID:12719478
Molecular Function	GO:0030246	carbohydrate binding	CLEC7A	IDA		Human	PMID:11567029
Molecular Function	GO:0001846	opsonin binding	Clec7a	IDA		Mouse	PMID:12163569
Molecular Function	GO:0038187	pattern recognition receptor activity	CLEC7A	IDA		Human	PMID:11567029
Molecular Function	GO:0030247	polysaccharide binding	Clec7a	IDA		Mouse	PMID:12719478
Molecular Function	GO:0030247	polysaccharide binding	Clec7a	IDA		Mouse	PMID:12163569
Molecular Function	GO:0030247	polysaccharide binding	Clec7a	IDA		Mouse	PMID:14707091
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:O60238	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q8N205	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:P48616	Human	PMID:23674515
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:O60238	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:P53801	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q01638	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q12983	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q16625	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q86UP2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q8N5M9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9BRL5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9BSE2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9BU27	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9BZ11-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9BZL3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9NRS4-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9NZG7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLEC7A	IPI	UniProtKB:Q9BSE2	Human	PMID:31515488
Cellular Component	GO:0009986	cell surface	CLEC7A	IDA		Human	PMID:24721111
Cellular Component	GO:0009986	cell surface	CLEC7A	IDA		Human	PMID:25251945
Cellular Component	GO:0005737	cytoplasm	CLEC7A	IDA		Human	PMID:24721111
Cellular Component	GO:0009897	external side of plasma membrane	Clec7a	IDA		Mouse	PMID:14707091
Cellular Component	GO:0009897	external side of plasma membrane	Clec7a	IDA		Mouse	PMID:12163569
Cellular Component	GO:0009897	external side of plasma membrane	Clec7a	IDA		Mouse	PMID:14726497
Cellular Component	GO:0009897	external side of plasma membrane	Clec7a	IDA		Mouse	PMID:12719478
Biological Process	GO:0008037	cell recognition	CLEC7A	IDA		Human	PMID:11567029
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	Clec7a	IDA		Mouse	PMID:12719478
Biological Process	GO:0098609	cell-cell adhesion	Clec7a	IDA		Mouse	PMID:14698225
Biological Process	GO:0071226	cellular response to molecule of fungal origin	CLEC7A	IDA		Human	PMID:22267217
Biological Process	GO:0016046	detection of fungus	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032491	detection of molecule of fungal origin	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0001879	detection of yeast	Clec7a	IDA		Mouse	PMID:14698225
Biological Process	GO:0006911	phagocytosis, engulfment	Clec7a	IDA		Mouse	PMID:14707091
Biological Process	GO:0006910	phagocytosis, recognition	CLEC7A	IDA		Human	PMID:11567029
Biological Process	GO:0006910	phagocytosis, recognition	Clec7a	IDA		Mouse	PMID:14707091
Biological Process	GO:1903431	positive regulation of cell maturation	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0030335	positive regulation of cell migration	CLEC7A	IMP		Human	PMID:24721111
Biological Process	GO:0008284	positive regulation of cell population proliferation	CLEC7A	IMP		Human	PMID:24721111
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	CLEC7A	IMP		Human	PMID:22267217
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	CLEC7A	IDA		Human	PMID:22267217
Biological Process	GO:0010628	positive regulation of gene expression	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	CLEC7A	IDA		Human	PMID:22267217
Biological Process	GO:0032733	positive regulation of interleukin-10 production	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032735	positive regulation of interleukin-12 production	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032743	positive regulation of interleukin-2 production	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032757	positive regulation of interleukin-8 production	CLEC7A	IMP		Human	PMID:25251945
Biological Process	GO:0051712	positive regulation of killing of cells of another organism	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0051251	positive regulation of lymphocyte activation	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	CLEC7A	IMP		Human	PMID:25251945
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0050766	positive regulation of phagocytosis	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0050766	positive regulation of phagocytosis	Clec7a	IDA		Mouse	PMID:14707091
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	CLEC7A	IMP		Human	PMID:22267217
Biological Process	GO:0060267	positive regulation of respiratory burst	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032930	positive regulation of superoxide anion generation	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Clec7a	IDA		Mouse	PMID:14707091
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Clec7a	IDA		Mouse	PMID:12719478
Biological Process	GO:0032729	positive regulation of type II interferon production	CLEC7A	IDA		Human	PMID:19358895
Biological Process	GO:0090303	positive regulation of wound healing	CLEC7A	IMP		Human	PMID:24721111
Biological Process	GO:0002238	response to molecule of fungal origin	Clec7a	IDA		Mouse	PMID:12719478
Biological Process	GO:0001878	response to yeast	Clec7a	IDA		Mouse	PMID:12719478
Biological Process	GO:0001878	response to yeast	Clec7a	IDA		Mouse	PMID:14726497
Biological Process	GO:0001878	response to yeast	Clec7a	IDA		Mouse	PMID:14707091

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern