Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLIC1
  • Mouse genes Clic1
  • Rat genes Clic1
  • Zfish genes clic1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clic1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CLIC1	HDA		Human	PMID:25468996
Molecular Function	GO:0005254	chloride channel activity	CLIC1	IDA		Human	PMID:9139710
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:Q99996	Human	PMID:12163479
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:P0DI81	Human	PMID:12681486
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:O15116	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:O75832	Human	PMID:24338975
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:Q4KMQ1-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:O15116	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:Q4KMQ1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:Q5HYW2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLIC1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Cellular Component	GO:0072562	blood microparticle	CLIC1	HDA		Human	PMID:22516433
Cellular Component	GO:0005737	cytoplasm	CLIC1	IDA		Human	PMID:10793131
Cellular Component	GO:0005737	cytoplasm	CLIC1	HDA		Human	PMID:16791210
Cellular Component	GO:0070062	extracellular exosome	CLIC1	IDA		Human	PMID:15326289
Cellular Component	GO:0070062	extracellular exosome	CLIC1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CLIC1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CLIC1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	CLIC1	HDA		Human	PMID:22664934
Cellular Component	GO:0016020	membrane	CLIC1	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Clic1	IDA		Mouse	PMID:19703605
Cellular Component	GO:0005635	nuclear envelope	CLIC1	IDA		Human	PMID:9139710
Cellular Component	GO:0005634	nucleus	CLIC1	HDA		Human	PMID:16791210
Cellular Component	GO:0005634	nucleus	Clic1	IDA		Mouse	PMID:19703605
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CLIC1	IDA		Human	PMID:12681486
Cellular Component	GO:0031982	vesicle	CLIC1	HDA		Human	PMID:19190083
Biological Process	GO:0006821	chloride transport	CLIC1	IDA		Human	PMID:9139710
Biological Process	GO:0070527	platelet aggregation	CLIC1	HMP		Human	PMID:23382103
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Clic1	IDA		Mouse	PMID:19703605
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Clic1	IDA		Mouse	PMID:19703605
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Clic1	IMP		Mouse	PMID:19703605

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern