Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLK1
  • Mouse genes Clk1
  • Rat genes Clk1
  • Zfish genes clk4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLK1	IPI	UniProtKB:O76083	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CLK1	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Clk1	IPI	UniProtKB:Q5ZRQ0	Mouse	MGI:MGI:5486542|PMID:18284575
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CLK1	IDA		Human	PMID:10480872
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Clk1	IDA		Mouse	PMID:1825055
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Clk1	IDA		Mouse	PMID:1986248
Molecular Function	GO:0004713	protein tyrosine kinase activity	Clk1	IDA		Mouse	PMID:1825055
Molecular Function	GO:0004713	protein tyrosine kinase activity	Clk1	IDA		Mouse	PMID:1986248
Cellular Component	GO:0005737	cytoplasm	Clk1	IDA		Rat	PMID:10954422|RGD:2316185
Cellular Component	GO:0005634	nucleus	Clk1	IDA		Mouse	PMID:9307018
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Clk1	IDA		Mouse	PMID:1986248
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Clk1	IDA		Mouse	PMID:1825055
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Clk1	IDA		Mouse	PMID:1986248
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Clk1	IDA		Mouse	MGI:MGI:79278
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Clk1	IDA		Mouse	PMID:1986248
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Clk1	IDA		Mouse	PMID:1825055
Biological Process	GO:0046777	protein autophosphorylation	Clk1	IDA		Mouse	PMID:1825055
Biological Process	GO:0043484	regulation of RNA splicing	CLK1	IMP		Human	PMID:19168442

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern