Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLN5
  • Mouse genes Cln5
  • Rat genes Cln5
  • Zfish genes cln5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cln5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005537	mannose binding	CLN5	IDA		Human	PMID:16399764
Molecular Function	GO:0005515	protein binding	CLN5	IPI	UniProtKB:O14773	Human	PMID:12134079
Molecular Function	GO:0005515	protein binding	CLN5	IPI	UniProtKB:Q13286	Human	PMID:12134079
Molecular Function	GO:0005515	protein binding	CLN5	IPI	UniProtKB:Q13286	Human	PMID:14699076
Molecular Function	GO:0005515	protein binding	CLN5	IPI	UniProtKB:P20339	Human	PMID:22431521
Molecular Function	GO:0005515	protein binding	CLN5	IPI	UniProtKB:P51149	Human	PMID:22431521
Molecular Function	GO:0005515	protein binding	CLN5	IPI	UniProtKB:Q99523	Human	PMID:22431521
Molecular Function	GO:0005515	protein binding	Cln5	IPI	UniProtKB:O14773|UniProtKB:O88531|UniProtKB:O89023|UniProtKB:P50897|UniProtKB:P56480|UniProtKB:Q03265|UniProtKB:Q13286|UniProtKB:Q61124|UniProtKB:Q9NWW5|UniProtKB:Q9QUK3	Mouse	MGI:MGI:5795821|PMID:19941651
Cellular Component	GO:0005783	endoplasmic reticulum	CLN5	IDA		Human	PMID:12134079
Cellular Component	GO:0070062	extracellular exosome	CLN5	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	CLN5	IDA		Human	PMID:12134079
Cellular Component	GO:0005765	lysosomal membrane	CLN5	IDA		Human	PMID:12134079
Cellular Component	GO:0005764	lysosome	CLN5	IDA		Human	PMID:11971870
Cellular Component	GO:0005764	lysosome	CLN5	IDA		Human	PMID:19941651
Cellular Component	GO:0005764	lysosome	CLN5	IDA		Human	PMID:22431521
Cellular Component	GO:0005764	lysosome	Cln5	IDA		Mouse	MGI:MGI:5795821|PMID:19941651
Cellular Component	GO:0005764	lysosome	Cln5	IDA		Mouse	PMID:29514215
Cellular Component	GO:0005764	lysosome	Cln5	IDA		Mouse	PMID:15207259
Cellular Component	GO:0016020	membrane	CLN5	IDA		Human	PMID:12134079
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CLN5	IDA		Human	PMID:10992246
Cellular Component	GO:0005775	vacuolar lumen	Cln5	IDA		Mouse	PMID:15207259
Biological Process	GO:0009060	aerobic respiration	cln5	IMP	ZFIN:ZDB-MRPHLNO-221005-1	Zfish	PMID:35681535
Biological Process	GO:0007420	brain development	CLN5	IEP		Human	PMID:10992246
Biological Process	GO:0070085	glycosylation	CLN5	IDA		Human	PMID:16399764
Biological Process	GO:0007042	lysosomal lumen acidification	CLN5	IMP		Human	PMID:11722572
Biological Process	GO:0007040	lysosome organization	Cln5	IMP	MGI:MGI:3521802	Mouse	PMID:15459177
Biological Process	GO:0022008	neurogenesis	CLN5	IEP		Human	PMID:10992246
Biological Process	GO:0072592	oxygen metabolic process	cln5	IMP	ZFIN:ZDB-MRPHLNO-221005-1	Zfish	PMID:35681535
Biological Process	GO:1904426	positive regulation of GTP binding	CLN5	IMP		Human	PMID:22431521
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	CLN5	IMP		Human	PMID:22431521
Biological Process	GO:0006465	signal peptide processing	CLN5	IDA		Human	PMID:20052765
Biological Process	GO:0036269	swimming behavior	cln5	IMP	ZFIN:ZDB-MRPHLNO-221005-1	Zfish	PMID:35681535
Biological Process	GO:0007601	visual perception	Cln5	IMP	MGI:MGI:3521802	Mouse	PMID:15459177

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern