Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLN6
  • Mouse genes Cln6
  • Rat genes Cln6
  • Zfish genes cln6a,cln6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cln6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035727	lysophosphatidic acid binding	CLN6	IDA		Human	PMID:18317235
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q13286	Human	PMID:17237713
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q16555	Human	PMID:19235893
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q3UMW8	Human	PMID:19941651
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:A0A142I5B9	Human	PMID:30177828
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:A1A5C7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:O00559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:O14863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:P34910-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:P43628	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q5T7V8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q7Z5B4-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q8IUN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q8IV31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q8N386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q9H400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:Q9Y6I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:O00308	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CLN6	IPI	UniProtKB:P29323-3	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	CLN6	IDA		Human	PMID:15010453
Molecular Function	GO:0120146	sulfatide binding	CLN6	IDA		Human	PMID:18317235
Cellular Component	GO:0005769	early endosome	CLN6	IDA		Human	PMID:17237713
Cellular Component	GO:0005783	endoplasmic reticulum	CLN6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	CLN6	IDA		Human	PMID:15265688
Cellular Component	GO:0005783	endoplasmic reticulum	CLN6	IDA		Human	PMID:19941651
Cellular Component	GO:0005788	endoplasmic reticulum lumen	CLN6	IDA		Human	PMID:15010453
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CLN6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	CLN6	HDA		Human	PMID:19946888
Cellular Component	GO:0045121	membrane raft	CLN6	IDA		Human	PMID:17237713
Cellular Component	GO:0005730	nucleolus	CLN6	IDA		Human	GO_REF:0000052
Biological Process	GO:0008203	cholesterol metabolic process	CLN6	IMP		Human	PMID:16857350
Biological Process	GO:0001573	ganglioside metabolic process	CLN6	IMP		Human	PMID:16857350
Biological Process	GO:0030203	glycosaminoglycan metabolic process	CLN6	IMP		Human	PMID:16857350
Biological Process	GO:0031987	locomotion involved in locomotory behavior	Cln6	IMP	MGI:MGI:2159328	Mouse	PMID:9600738
Biological Process	GO:0007042	lysosomal lumen acidification	CLN6	IMP		Human	PMID:11722572
Biological Process	GO:0007040	lysosome organization	Cln6	IMP	MGI:MGI:2159328	Mouse	PMID:26681805
Biological Process	GO:0007040	lysosome organization	Cln6	IMP	MGI:MGI:2159328	Mouse	PMID:9600738
Biological Process	GO:0009057	macromolecule catabolic process	Cln6	IMP	MGI:MGI:2159328	Mouse	PMID:15647513
Biological Process	GO:0045862	positive regulation of proteolysis	CLN6	IMP		Human	PMID:15010453
Biological Process	GO:0007601	visual perception	Cln6	IMP	MGI:MGI:2159328	Mouse	PMID:9600738

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern