Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CLNK
  • Mouse genes Clnk
  • Rat genes Clnk
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Clnk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CLNK	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	CLNK	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	CLNK	IPI	UniProtKB:Q14739	Human	PMID:26009488
Molecular Function	GO:0005515	protein binding	CLNK	IPI	UniProtKB:Q9UKV8	Human	PMID:26009488
Molecular Function	GO:0005515	protein binding	Clnk	IPI	UniProtKB:Q3U9G9|UniProtKB:Q8CJG0	Mouse	MGI:MGI:6355741|PMID:26009488
Molecular Function	GO:0005515	protein binding	Clnk	IPI	UniProtKB:P27870|UniProtKB:Q60631|UniProtKB:Q8CIH5	Mouse	MGI:MGI:2179131|PMID:10744659
Molecular Function	GO:0005515	protein binding	Clnk	IPI	UniProtKB:P14234	Mouse	MGI:MGI:3774350|PMID:16439675
Molecular Function	GO:0005515	protein binding	Clnk	IPI	PR:Q08481	Mouse	PMID:10562326
Molecular Function	GO:0044877	protein-containing complex binding	Clnk	IPI	UniProtKB:O35601,UniProtKB:P25911,UniProtKB:Q4V7G1	Mouse	MGI:MGI:2654969|PMID:12681493
Cellular Component	GO:0005737	cytoplasm	CLNK	IMP		Human	PMID:26009488
Cellular Component	GO:0042629	mast cell granule	Clnk	IDA		Mouse	MGI:MGI:2179131|PMID:10744659
Cellular Component	GO:0032991	protein-containing complex	Clnk	IMP		Mouse	MGI:MGI:2654969|PMID:12681493
Biological Process	GO:0043303	mast cell degranulation	Clnk	IMP		Mouse	MGI:MGI:2179131|PMID:10744659
Biological Process	GO:0032815	negative regulation of natural killer cell activation	Clnk	IMP		Mouse	MGI:MGI:3047506|PMID:15199160
Biological Process	GO:0032815	negative regulation of natural killer cell activation	Clnk	IMP		Mouse	MGI:MGI:3774350|PMID:16439675
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	Clnk	IMP		Mouse	MGI:MGI:3774350|PMID:16439675
Biological Process	GO:0010941	regulation of cell death	Clnk	IMP		Mouse	MGI:MGI:6355741|PMID:26009488
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Clnk	IMP		Mouse	MGI:MGI:2179131|PMID:10744659
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Clnk	IDA		Mouse	PMID:10562326

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern