Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CMKLR1
  • Mouse genes Cmklr1
  • Rat genes Cmklr1
  • Zfish genes cmklr1,cmklr1l1,cmklrl2,fpr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cmklr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097004	adipokinetic hormone binding	CMKLR1	IDA		Human	PMID:27716822
Molecular Function	GO:0097003	adipokinetic hormone receptor activity	CMKLR1	IDA		Human	PMID:27716822
Molecular Function	GO:0005515	protein binding	CMKLR1	IPI	UniProtKB:Q99969	Human	PMID:14530373
Cellular Component	GO:0005886	plasma membrane	CMKLR1	IDA		Human	PMID:14530373
Cellular Component	GO:0005886	plasma membrane	CMKLR1	IDA		Human	PMID:27716822
Biological Process	GO:0006935	chemotaxis	CMKLR1	IDA		Human	PMID:14530373
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CMKLR1	IDA		Human	PMID:14530373
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	CMKLR1	IDA		Human	PMID:27716822
Biological Process	GO:0032695	negative regulation of interleukin-12 production	Cmklr1	IMP		Mouse	MGI:MGI:5009414|PMID:15753205
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	CMKLR1	IDA		Human	PMID:15753205
Biological Process	GO:0002283	neutrophil activation involved in immune response	fpr1	IMP	ZFIN:ZDB-MRPHLNO-121227-1	Zfish	PMID:22980327
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Cmklr1	IMP		Mouse	MGI:MGI:5790918|PMID:26972253
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Cmklr1	IMP		Mouse	MGI:MGI:3758402|PMID:17635925
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	CMKLR1	IMP		Human	PMID:19443732
Biological Process	GO:0050848	regulation of calcium-mediated signaling	CMKLR1	IDA		Human	PMID:14530373

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern