Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNGB1
  • Mouse genes Cngb1
  • Rat genes Cngb1
  • Zfish genes cngb1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cngb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030553	cGMP binding	CNGB1	IDA		Human	PMID:24164424
Molecular Function	GO:0043855	cyclic nucleotide-gated monoatomic ion channel activity	Cngb1	IMP	MGI:MGI:3527896	Mouse	PMID:16980309
Molecular Function	GO:0005222	intracellular cAMP-activated cation channel activity	Cngb1	IDA		Rat	PMID:22786723|RGD:7241219
Molecular Function	GO:0005223	intracellular cGMP-activated cation channel activity	CNGB1	IDA		Human	PMID:24164424
Molecular Function	GO:0005223	intracellular cGMP-activated cation channel activity	Cngb1	IDA		Rat	PMID:21809342|RGD:6902901
Molecular Function	GO:0005223	intracellular cGMP-activated cation channel activity	Cngb1	IDA		Rat	PMID:22786723|RGD:7241219
Molecular Function	GO:0005515	protein binding	CNGB1	IPI	UniProtKB:Q5ICW4	Human	PMID:20890309
Molecular Function	GO:0044877	protein-containing complex binding	Cngb1	IDA		Rat	PMID:22786723|RGD:7241219
Cellular Component	GO:0017071	intracellular cyclic nucleotide activated cation channel complex	Cngb1	IDA		Rat	PMID:21809342|RGD:6902901
Cellular Component	GO:0017071	intracellular cyclic nucleotide activated cation channel complex	Cngb1	IDA		Rat	PMID:22786723|RGD:7241219
Cellular Component	GO:0016020	membrane	Cngb1	IDA		Mouse	PMID:15634774
Cellular Component	GO:0001750	photoreceptor outer segment	Cngb1	IDA		Mouse	PMID:22183407
Cellular Component	GO:0005886	plasma membrane	Cngb1	IDA		Rat	PMID:22786723|RGD:7241219
Cellular Component	GO:0043195	terminal bouton	Cngb1	IDA		Rat	PMID:21809342|RGD:6902901
Cellular Component	GO:1902495	transmembrane transporter complex	CNGB1	IDA		Human	PMID:24164424
Biological Process	GO:0050911	detection of chemical stimulus involved in sensory perception of smell	Cngb1	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	CNGB1	IMP		Human	PMID:15557452
Biological Process	GO:0099105	ion channel modulating, G protein-coupled receptor signaling pathway	Cngb1	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0051899	membrane depolarization	Cngb1	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0006812	monoatomic cation transport	CNGB1	IDA		Human	PMID:24164424
Biological Process	GO:0021630	olfactory nerve maturation	Cngb1	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0045494	photoreceptor cell maintenance	Cngb1	IMP	MGI:MGI:3527896	Mouse	PMID:15634774
Biological Process	GO:0035845	photoreceptor cell outer segment organization	Cngb1	IMP	MGI:MGI:3851598	Mouse	PMID:23178122
Biological Process	GO:0007602	phototransduction	Cngb1	IMP	MGI:MGI:3527896	Mouse	PMID:15634774
Biological Process	GO:0010628	positive regulation of gene expression	Cngb1	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0033365	protein localization to organelle	Cngb1	IMP	MGI:MGI:3527896	Mouse	PMID:16980309
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Cngb1	IDA		Rat	PMID:21809342|RGD:6902901
Biological Process	GO:1990834	response to odorant	Cngb1	IMP		Mouse	MGI:MGI:5817509|PMID:28053034
Biological Process	GO:0001895	retina homeostasis	CNGB1	IMP		Human	PMID:15557452
Biological Process	GO:0007608	sensory perception of smell	Cngb1	IMP	MGI:MGI:3527896	Mouse	PMID:16980309

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern