Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNN2
  • Mouse genes Cnn2
  • Rat genes Cnn2
  • Zfish genes cnn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CNN2	HDA		Human	PMID:25468996
Cellular Component	GO:0005925	focal adhesion	CNN2	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	CNN2	HDA		Human	PMID:19946888
Cellular Component	GO:0001725	stress fiber	CNN2	IDA		Human	PMID:16236705
Biological Process	GO:0071260	cellular response to mechanical stimulus	CNN2	IDA		Human	PMID:16236705
Biological Process	GO:0051649	establishment of localization in cell	Cnn2	IMP	MGI:MGI:3820422	Mouse	PMID:18617524
Biological Process	GO:0030097	hemopoiesis	Cnn2	IMP	MGI:MGI:3820423	Mouse	PMID:18617524
Biological Process	GO:1905517	macrophage migration	Cnn2	IMP	MGI:MGI:3820422	Mouse	PMID:18617524
Biological Process	GO:1905522	negative regulation of macrophage migration	Cnn2	IMP	MGI:MGI:3820422	Mouse	PMID:18617524
Biological Process	GO:0050765	negative regulation of phagocytosis	Cnn2	IMP	MGI:MGI:3820422	Mouse	PMID:18617524
Biological Process	GO:0006909	phagocytosis	Cnn2	IMP	MGI:MGI:3820422	Mouse	PMID:18617524
Biological Process	GO:0010628	positive regulation of gene expression	Cnn2	IMP	MGI:MGI:3820423	Mouse	PMID:18617524
Biological Process	GO:0032970	regulation of actin filament-based process	CNN2	IDA		Human	PMID:16236705
Biological Process	GO:0043535	regulation of blood vessel endothelial cell migration	cnn2	IMP	ZFIN:ZDB-MRPHLNO-060315-2	Zfish	PMID:16317011
Biological Process	GO:0070663	regulation of leukocyte proliferation	Cnn2	IMP	MGI:MGI:3820422	Mouse	PMID:18617524
Biological Process	GO:0070663	regulation of leukocyte proliferation	Cnn2	IMP	MGI:MGI:3820421	Mouse	PMID:18617524
Biological Process	GO:0070663	regulation of leukocyte proliferation	Cnn2	IMP	MGI:MGI:3820423	Mouse	PMID:18617524
Biological Process	GO:0043408	regulation of MAPK cascade	cnn2	IMP		Zfish	PMID:16317011
Biological Process	GO:0048545	response to steroid hormone	cnn2	IEP		Zfish	PMID:28265462
Biological Process	GO:0042060	wound healing	Cnn2	IMP	MGI:MGI:3820423	Mouse	PMID:18617524

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern