Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNOT1
  • Mouse genes Cnot1
  • Rat genes Cnot1
  • Zfish genes cnot1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnot1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070016	armadillo repeat domain binding	CNOT1	IPI	UniProtKB:Q92600	Human	PMID:24768540
Molecular Function	GO:0060090	molecular adaptor activity	CNOT1	IDA		Human	PMID:22977175
Molecular Function	GO:0030331	nuclear estrogen receptor binding	CNOT1	IDA		Human	PMID:16778766
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	CNOT1	IDA		Human	PMID:16778766
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	CNOT1	IDA		Human	PMID:21976065
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9NZN8	Human	PMID:10637334
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UFF9	Human	PMID:10637334
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:O75175	Human	PMID:16778766
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9NZN8	Human	PMID:16778766
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UFF9	Human	PMID:16778766
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q96LI5	Human	PMID:17452450
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9ULM6	Human	PMID:17452450
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P50616	Human	PMID:18377426
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q86TB9	Human	PMID:20584987
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P22893	Human	PMID:21278420
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UIV1	Human	PMID:21278420
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q8NDV7	Human	PMID:21981923
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9HCJ0	Human	PMID:21981923
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UPQ9	Human	PMID:21981923
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q96LI5	Human	PMID:21984185
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9HCJ0	Human	PMID:21984185
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q96LI5	Human	PMID:22977175
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UFF9	Human	PMID:22977175
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UIV1	Human	PMID:22977175
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9ULM6	Human	PMID:22977175
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UKZ1	Human	PMID:23232451
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9HCJ0	Human	PMID:23463101
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P26651	Human	PMID:23644599
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P60321	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P60323	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q8WY41	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q8NDV7	Human	PMID:24768540
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9HCJ0	Human	PMID:24768540
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P26651	Human	PMID:25038453
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:O75175	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:P50616	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q96LI5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9NZN8	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UFF9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UIV1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9UKZ1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9ULM6	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q9NRA8	Human	PMID:27342281
Molecular Function	GO:0005515	protein binding	CNOT1	IPI	UniProtKB:Q3ZCQ2	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	Cnot1	IPI	UniProtKB:P60322	Mouse	MGI:MGI:4431145|PMID:20133598
Molecular Function	GO:0005515	protein binding	Cnot1	IPI	PR:Q8VEG6	Mouse	PMID:17452450
Molecular Function	GO:0019904	protein domain specific binding	CNOT1	IPI	UniProtKB:P26196	Human	PMID:24768540
Molecular Function	GO:0003723	RNA binding	CNOT1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CNOT1	HDA		Human	PMID:22681889
Cellular Component	GO:0030014	CCR4-NOT complex	CNOT1	IDA		Human	PMID:19558367
Cellular Component	GO:0005829	cytosol	CNOT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	CNOT1	HDA		Human	PMID:22664934
Cellular Component	GO:0016020	membrane	CNOT1	HDA		Human	PMID:19946888
Cellular Component	GO:0000932	P-body	CNOT1	IDA		Human	PMID:21976065
Cellular Component	GO:0000932	P-body	Cnot1	IDA		Mouse	MGI:MGI:4431145|PMID:20133598
Biological Process	GO:0048589	developmental growth	cnot1	IMP	ZFIN:ZDB-MRPHLNO-151109-8	Zfish	PMID:25533962
Biological Process	GO:0035195	miRNA-mediated gene silencing	CNOT1	IDA		Human	PMID:23172285
Biological Process	GO:0035195	miRNA-mediated gene silencing	CNOT1	IDA		Human	PMID:24768540
Biological Process	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	CNOT1	IDA		Human	PMID:16778766
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	CNOT1	IDA		Human	PMID:16778766
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CNOT1	IDA		Human	PMID:16778766
Biological Process	GO:0017148	negative regulation of translation	CNOT1	IDA		Human	PMID:24736845
Biological Process	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly	CNOT1	IDA		Human	PMID:21976065
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	CNOT1	IMP		Human	PMID:22977175
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	CNOT1	IMP		Human	PMID:21278420
Biological Process	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	CNOT1	IMP		Human	PMID:21278420
Biological Process	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	CNOT1	IDA		Human	PMID:23644599
Biological Process	GO:2000036	regulation of stem cell population maintenance	CNOT1	IMP		Human	PMID:22367759
Biological Process	GO:2000036	regulation of stem cell population maintenance	Cnot1	IMP		Mouse	MGI:MGI:5487505|PMID:22367759
Biological Process	GO:0001829	trophectodermal cell differentiation	Cnot1	IMP		Mouse	MGI:MGI:5487505|PMID:22367759

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern