Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNOT7
  • Mouse genes Cnot7
  • Rat genes Cnot7
  • Zfish genes cnot7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnot7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	CNOT7	IDA		Human	PMID:15769875
Molecular Function	GO:0140297	DNA-binding transcription factor binding	CNOT7	IPI	UniProtKB:P42224	Human	PMID:23386060
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	CNOT7	IDA		Human	PMID:15769875
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	CNOT7	IDA		Human	PMID:19276069
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	CNOT7	IDA		Human	PMID:21336257
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	CNOT7	IDA		Human	PMID:31439799
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	Cnot7	IMP		Mouse	PMID:18625844
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P62324	Human	PMID:11136725
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P78543	Human	PMID:11136725
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9ULM6	Human	PMID:11747467
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q96LI5	Human	PMID:17452450
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P50616	Human	PMID:18377426
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P50616	Human	PMID:19276069
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9UKV8	Human	PMID:19716330
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q86TB9	Human	PMID:20584987
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P22893	Human	PMID:20595389
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P50616	Human	PMID:20595394
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:A5YKK6	Human	PMID:21278420
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P22893	Human	PMID:21278420
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P50616	Human	PMID:21336257
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P62324	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9HCJ0	Human	PMID:21981923
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9UKV8	Human	PMID:21981923
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q96LI5	Human	PMID:21984185
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9HCJ0	Human	PMID:21984185
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:A5YKK6	Human	PMID:22977175
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P26651	Human	PMID:25038453
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P26651	Human	PMID:25106868
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P47974	Human	PMID:25106868
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q07352	Human	PMID:25106868
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P78543	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q14106	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:A5YKK6	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P62324	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P50616	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q14106	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q96LI5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P50616	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P78543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q14106	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q96LI5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9NUJ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:Q9NY30	Human	PMID:32502391
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CNOT7	IPI	UniProtKB:P62324	Human	PMID:9820826
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:O70552|UniProtKB:P06730	Mouse	MGI:MGI:5918927|PMID:27065194
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:P78543|UniProtKB:Q04211	Mouse	MGI:MGI:3785219|PMID:18337750
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:O70552	Mouse	MGI:MGI:5918927|PMID:27065194
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:Q8VEG6	Mouse	MGI:MGI:3828348|PMID:17452450
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:Q04211	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:P60322	Mouse	MGI:MGI:4431145|PMID:20133598
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:Q9UKZ1	Mouse	MGI:MGI:5487738|PMID:23232451
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:Q8VEG6	Mouse	MGI:MGI:5305011|PMID:21897366
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:P62324|UniProtKB:P78543	Mouse	MGI:MGI:5493222|PMID:9712883
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:Q14106	Mouse	MGI:MGI:5916992|PMID:19838187
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	UniProtKB:Q14106	Mouse	MGI:MGI:5915704|PMID:23340509
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	PR:O35710	Mouse	PMID:18625844
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	PR:Q8BGF7	Mouse	PMID:18625844
Molecular Function	GO:0005515	protein binding	Cnot7	IPI	RGD:2224	Rat	PMID:9820826|RGD:2298944
Molecular Function	GO:0004532	RNA exonuclease activity	CNOT7	IDA		Human	PMID:19276069
Molecular Function	GO:0003714	transcription corepressor activity	CNOT7	IMP		Human	PMID:23386060
Cellular Component	GO:0030014	CCR4-NOT complex	CNOT7	IDA		Human	PMID:19558367
Cellular Component	GO:0030014	CCR4-NOT complex	CNOT7	IDA		Human	PMID:21336257
Cellular Component	GO:0030014	CCR4-NOT complex	Cnot7	IPI	UniProtKB:P31384	Mouse	PMID:7791755
Cellular Component	GO:0005737	cytoplasm	CNOT7	IMP		Human	PMID:23386060
Cellular Component	GO:0005737	cytoplasm	Cnot7	IDA		Mouse	PMID:18625844
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	CNOT7	IDA		Human	PMID:31439799
Cellular Component	GO:0016020	membrane	CNOT7	HDA		Human	PMID:19946888
Cellular Component	GO:0016604	nuclear body	CNOT7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	CNOT7	IMP		Human	PMID:23386060
Cellular Component	GO:0005634	nucleus	CNOT7	IDA		Human	PMID:9820826
Cellular Component	GO:0005634	nucleus	Cnot7	IDA		Mouse	PMID:18625844
Cellular Component	GO:0005634	nucleus	Cnot7	IDA		Rat	PMID:9820826|RGD:2298944
Cellular Component	GO:0000932	P-body	Cnot7	IDA		Mouse	MGI:MGI:4431145|PMID:20133598
Cellular Component	GO:0000932	P-body	Cnot7	IDA		Mouse	PMID:18625844
Biological Process	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	CNOT7	IDA		Human	PMID:31439799
Biological Process	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	Cnot7	IGI	MGI:MGI:109382	Mouse	PMID:18625844
Biological Process	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	Cnot7	IMP		Mouse	PMID:18625844
Biological Process	GO:0051607	defense response to virus	CNOT7	IMP		Human	PMID:23386060
Biological Process	GO:0043928	exonucleolytic catabolism of deadenylated mRNA	CNOT7	IDA		Human	PMID:20065043
Biological Process	GO:0043928	exonucleolytic catabolism of deadenylated mRNA	CNOT7	IDA		Human	PMID:21336257
Biological Process	GO:0006402	mRNA catabolic process	cnot7	IMP		Zfish	PMID:28557307
Biological Process	GO:0008285	negative regulation of cell population proliferation	CNOT7	IDA		Human	PMID:19276069
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CNOT7	IMP		Human	PMID:23386060
Biological Process	GO:0010629	negative regulation of gene expression	CNOT7	IMP		Human	PMID:25038453
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	CNOT7	IMP		Human	PMID:23386060
Biological Process	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	Cnot7	IMP		Mouse	PMID:18625844
Biological Process	GO:0033962	P-body assembly	Cnot7	IGI	MGI:MGI:109382	Mouse	PMID:18625844
Biological Process	GO:0008284	positive regulation of cell population proliferation	CNOT7	IMP		Human	PMID:19605561
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	CNOT7	IMP		Human	PMID:23386060
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	CNOT7	IMP		Human	PMID:25038453
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	CNOT7	IMP		Human	PMID:21278420
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Cnot7	IMP		Mouse	MGI:MGI:5486537|PMID:19716330
Biological Process	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	CNOT7	IMP		Human	PMID:21278420
Biological Process	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	Cnot7	IMP		Mouse	MGI:MGI:5486537|PMID:19716330
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Cnot7	IDA		Mouse	PMID:7791755
Biological Process	GO:0045070	positive regulation of viral genome replication	CNOT7	IMP		Human	PMID:23386060
Biological Process	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	CNOT7	IMP		Human	PMID:23386060
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	Cnot7	IMP		Mouse	MGI:MGI:3807625|PMID:18625844
Biological Process	GO:0031047	RNA-mediated gene silencing	Cnot7	IMP		Mouse	MGI:MGI:5486537|PMID:19716330

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern