Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNP
  • Mouse genes Cnp
  • Rat genes Cnp
  • Zfish genes cnp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	Cnp	IDA		Mouse	PMID:12590258
Molecular Function	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	Cnp	IDA		Rat	PMID:19357238|RGD:6480491
Molecular Function	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	cnp	IDA		Zfish	PMID:16765331
Molecular Function	GO:0030551	cyclic nucleotide binding	Cnp	IDA		Rat	PMID:19357238|RGD:6480491
Molecular Function	GO:0005515	protein binding	CNP	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	CNP	IPI	UniProtKB:P42858	Human	PMID:32814053
Cellular Component	GO:0042995	cell projection	Cnp	IDA		Rat	PMID:16051705|RGD:6483360
Cellular Component	GO:0005737	cytoplasm	CNP	IDA		Human	PMID:12379507
Cellular Component	GO:0005737	cytoplasm	Cnp	IDA		Mouse	PMID:29350434
Cellular Component	GO:0005737	cytoplasm	Cnp	IDA		Rat	PMID:16876328|RGD:6483359
Cellular Component	GO:0005829	cytosol	cnp	IDA		Zfish	PMID:16765331
Cellular Component	GO:0070062	extracellular exosome	CNP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CNP	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	CNP	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	CNP	IDA		Human	PMID:12379507
Cellular Component	GO:0016020	membrane	CNP	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Cnp	IDA		Mouse	PMID:12590258
Cellular Component	GO:0005902	microvillus	Cnp	IDA		Rat	PMID:16876328|RGD:6483359
Cellular Component	GO:0005743	mitochondrial inner membrane	Cnp	IDA		Rat	PMID:19357238|RGD:6480491
Cellular Component	GO:0005741	mitochondrial outer membrane	Cnp	IDA		Rat	PMID:19357238|RGD:6480491
Cellular Component	GO:0043209	myelin sheath	Cnp	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0043209	myelin sheath	Cnp	IDA		Mouse	PMID:24101522
Cellular Component	GO:0043209	myelin sheath	Cnp	IDA		Mouse	PMID:28251676
Cellular Component	GO:0043209	myelin sheath	Cnp	IDA		Rat	PMID:17960831|RGD:10047364
Cellular Component	GO:0035748	myelin sheath abaxonal region	Cnp	IDA		Rat	PMID:16051705|RGD:6483360
Cellular Component	GO:0035749	myelin sheath adaxonal region	Cnp	IDA		Rat	PMID:16051705|RGD:6483360
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cnp	IDA		Rat	PMID:11842207|RGD:1298767
Cellular Component	GO:0005886	plasma membrane	CNP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Cnp	IDA		Rat	PMID:11842207|RGD:1298767
Cellular Component	GO:0031143	pseudopodium	Cnp	IDA		Rat	PMID:16876328|RGD:6483359
Biological Process	GO:0008344	adult locomotory behavior	Cnp	IMP	MGI:MGI:3051635	Mouse	PMID:12590258
Biological Process	GO:0007568	aging	Cnp	IEP		Rat	PMID:21284091|RGD:6483356
Biological Process	GO:0031103	axon regeneration	cnp	IDA		Zfish	PMID:10098837
Biological Process	GO:0007409	axonogenesis	Cnp	IMP	MGI:MGI:3051635	Mouse	PMID:12590258
Biological Process	GO:0030900	forebrain development	Cnp	IEP		Rat	PMID:16876328|RGD:6483359
Biological Process	GO:0000226	microtubule cytoskeleton organization	Cnp	IMP		Rat	PMID:11842207|RGD:1298767
Biological Process	GO:0048709	oligodendrocyte differentiation	Cnp	IMP		Mouse	PMID:19139271
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Cnp	IMP		Rat	PMID:19357238|RGD:6480491
Biological Process	GO:0032496	response to lipopolysaccharide	Cnp	IEP		Rat	PMID:17000237|RGD:6483342
Biological Process	GO:0009636	response to toxic substance	Cnp	IDA		Mouse	PMID:20578039
Biological Process	GO:0021762	substantia nigra development	CNP	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern