Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cnr1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CNR1
- Mouse genes Cnr1
- Rat genes Cnr1
- Zfish genes cnr1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004949	cannabinoid receptor activity	CNR1	IDA		Human	PMID:18761332
Molecular Function	GO:0004949	cannabinoid receptor activity	Cnr1	IMP		Mouse	PMID:27826249
Molecular Function	GO:0004949	cannabinoid receptor activity	Cnr1	IMP		Mouse	PMID:27828947
Molecular Function	GO:0004949	cannabinoid receptor activity	Cnr1	IMP		Rat	PMID:2165569\|RGD:1298770
Molecular Function	GO:0042802	identical protein binding	CNR1	IPI	UniProtKB:P21554	Human	PMID:20590567
Molecular Function	GO:0042802	identical protein binding	CNR1	IPI	UniProtKB:P21554	Human	PMID:28734930
Molecular Function	GO:0005515	protein binding	CNR1	IPI	UniProtKB:P29274	Human	PMID:17356572
Molecular Function	GO:0005515	protein binding	CNR1	IPI	UniProtKB:Q96F85	Human	PMID:17895407
Molecular Function	GO:0005515	protein binding	CNR1	IPI	UniProtKB:P29274	Human	PMID:23296780
Molecular Function	GO:0005515	protein binding	CNR1	IPI	UniProtKB:P29274	Human	PMID:28102227
Molecular Function	GO:0005515	protein binding	Cnr1	IPI	UniProtKB:P30543	Rat	PMID:17356572\|RGD:8554571
Molecular Function	GO:0005515	protein binding	Cnr1	IPI	UniProtKB:Q5M7A7	Rat	PMID:17895407\|RGD:13461761
Cellular Component	GO:0015629	actin cytoskeleton	CNR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030424	axon	Cnr1	IDA		Mouse	PMID:20962221
Cellular Component	GO:0098982	GABA-ergic synapse	Cnr1	IDA		Mouse	PMID:11516401
Cellular Component	GO:0098982	GABA-ergic synapse	Cnr1	IMP		Mouse	PMID:11516401
Cellular Component	GO:0098982	GABA-ergic synapse	Cnr1	IDA		Mouse	PMID:27828947
Cellular Component	GO:0098982	GABA-ergic synapse	Cnr1	IMP		Mouse	PMID:27828947
Cellular Component	GO:0098978	glutamatergic synapse	Cnr1	IMP		Mouse	PMID:11516401
Cellular Component	GO:0098978	glutamatergic synapse	Cnr1	IDA		Mouse	PMID:11516401
Cellular Component	GO:0098978	glutamatergic synapse	Cnr1	IMP		Mouse	PMID:27828947
Cellular Component	GO:0098978	glutamatergic synapse	Cnr1	IDA		Mouse	PMID:27828947
Cellular Component	GO:0030426	growth cone	Cnr1	IDA		Mouse	PMID:20962221
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Cnr1	IDA		Rat	PMID:19906012\|RGD:2314635
Cellular Component	GO:0045121	membrane raft	Cnr1	IDA		Rat	PMID:21895628\|RGD:10047252
Cellular Component	GO:0005739	mitochondrion	Cnr1	IDA		Mouse	PMID:27826249
Cellular Component	GO:0005739	mitochondrion	Cnr1	IDA		Mouse	PMID:27828947
Cellular Component	GO:0005886	plasma membrane	CNR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CNR1	IDA		Human	PMID:17895407
Cellular Component	GO:0005886	plasma membrane	Cnr1	IDA		Rat	PMID:17895407\|RGD:13461761
Cellular Component	GO:0042734	presynaptic membrane	Cnr1	IDA		Mouse	MGI:MGI:5819353\|PMID:16540577
Cellular Component	GO:0042734	presynaptic membrane	Cnr1	IDA		Mouse	PMID:27828947
Cellular Component	GO:0042734	presynaptic membrane	Cnr1	IMP		Mouse	PMID:27828947
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	CNR1	IDA		Human	PMID:18761332
Biological Process	GO:0007568	aging	Cnr1	IMP		Rat	PMID:19679649\|RGD:2314647
Biological Process	GO:0007413	axonal fasciculation	Cnr1	IMP	MGI:MGI:1857736	Mouse	PMID:20962221
Biological Process	GO:0007413	axonal fasciculation	cnr1	IMP	ZFIN:ZDB-MRPHLNO-080805-1	Zfish	PMID:18378465
Biological Process	GO:0007413	axonal fasciculation	cnr1	IMP	ZFIN:ZDB-MRPHLNO-080805-2	Zfish	PMID:18378465
Biological Process	GO:0007409	axonogenesis	cnr1	IMP	ZFIN:ZDB-MRPHLNO-080805-1	Zfish	PMID:18378465
Biological Process	GO:0007409	axonogenesis	cnr1	IMP	ZFIN:ZDB-MRPHLNO-080805-2	Zfish	PMID:18378465
Biological Process	GO:0038171	cannabinoid signaling pathway	CNR1	IDA		Human	PMID:17895407
Biological Process	GO:0038171	cannabinoid signaling pathway	Cnr1	IMP		Mouse	MGI:MGI:5819353\|PMID:16540577
Biological Process	GO:0038171	cannabinoid signaling pathway	Cnr1	IDA		Rat	PMID:17895407\|RGD:13461761
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Cnr1	IMP		Rat	PMID:2165569\|RGD:1298770
Biological Process	GO:0042593	glucose homeostasis	Cnr1	IPI	MGI:MGI:2684950	Mouse	PMID:23954414
Biological Process	GO:0007611	learning or memory	Cnr1	IMP		Rat	PMID:19880592\|RGD:2314636
Biological Process	GO:0008610	lipid biosynthetic process	cnr1	IMP	ZFIN:ZDB-GENO-130930-7	Zfish	PMID:23315130
Biological Process	GO:0001889	liver development	cnr1	IGI	ZFIN:ZDB-GENE-090812-3	Zfish	PMID:26884397
Biological Process	GO:0001889	liver development	cnr1	IMP	ZFIN:ZDB-GENO-170314-1	Zfish	PMID:26884397
Biological Process	GO:0001889	liver development	cnr1	IGI	ZFIN:ZDB-GENE-070410-8	Zfish	PMID:26884397
Biological Process	GO:0060135	maternal process involved in female pregnancy	Cnr1	IEP		Rat	PMID:19860893\|RGD:2316191
Biological Process	GO:0007613	memory	Cnr1	IDA		Rat	PMID:19666083\|RGD:2314648
Biological Process	GO:0006555	methionine metabolic process	cnr1	IMP	ZFIN:ZDB-GENO-170314-1	Zfish	PMID:26884397
Biological Process	GO:0045759	negative regulation of action potential	Cnr1	IMP		Rat	PMID:20067581\|RGD:2316187
Biological Process	GO:0045776	negative regulation of blood pressure	Cnr1	IMP		Rat	PMID:19295473\|RGD:2314676
Biological Process	GO:0033602	negative regulation of dopamine secretion	Cnr1	IMP		Rat	PMID:19187091\|RGD:2314679
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	Cnr1	IMP		Rat	PMID:19724020\|RGD:2314644
Biological Process	GO:0033004	negative regulation of mast cell activation	Cnr1	IDA		Rat	PMID:18552882\|RGD:2316220
Biological Process	GO:0043271	negative regulation of monoatomic ion transport	Cnr1	IDA		Rat	PMID:19463903\|RGD:2314666
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	Cnr1	IMP		Rat	PMID:18561998\|RGD:2316219
Biological Process	GO:0014063	negative regulation of serotonin secretion	Cnr1	IMP		Rat	PMID:30217553\|RGD:15023474
Biological Process	GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	Cnr1	IMP		Rat	PMID:19282305\|RGD:2314677
Biological Process	GO:0043065	positive regulation of apoptotic process	Cnr1	IMP		Rat	PMID:19560819\|RGD:2314660
Biological Process	GO:0045777	positive regulation of blood pressure	Cnr1	IMP		Rat	PMID:19553924\|RGD:2314662
Biological Process	GO:2000253	positive regulation of feeding behavior	cnr1	IMP	ZFIN:ZDB-MRPHLNO-130312-11	Zfish	PMID:23300705
Biological Process	GO:0031622	positive regulation of fever generation	Cnr1	IMP		Rat	PMID:19681872\|RGD:2314645
Biological Process	GO:0010976	positive regulation of neuron projection development	Cnr1	IDA		Rat	PMID:19861414\|RGD:2314637
Biological Process	GO:0060259	regulation of feeding behavior	Cnr1	IMP		Rat	PMID:19575185\|RGD:2314659
Biological Process	GO:0050796	regulation of insulin secretion	Cnr1	IMP		Rat	PMID:19644453\|RGD:2314628
Biological Process	GO:0019216	regulation of lipid metabolic process	Cnr1	IMP		Rat	PMID:19325539\|RGD:2314630
Biological Process	GO:0060405	regulation of penile erection	Cnr1	IMP		Rat	PMID:17850365\|RGD:2314634
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Cnr1	IMP		Mouse	PMID:11516401
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Cnr1	IDA		Mouse	PMID:11516401
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	Cnr1	IMP		Rat	PMID:19725112\|RGD:2314643
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	Cnr1	IMP		Rat	PMID:19725112\|RGD:2314643
Biological Process	GO:0042220	response to cocaine	Cnr1	IMP		Rat	PMID:19401177\|RGD:2314673
Biological Process	GO:0045471	response to ethanol	Cnr1	IMP		Rat	PMID:19860799\|RGD:2314638
Biological Process	GO:0032496	response to lipopolysaccharide	Cnr1	IMP		Rat	PMID:19295473\|RGD:2314676
Biological Process	GO:0032496	response to lipopolysaccharide	Cnr1	IMP		Rat	PMID:19681872\|RGD:2314645
Biological Process	GO:0043278	response to morphine	Cnr1	IMP		Rat	PMID:19463710\|RGD:2314667
Biological Process	GO:0043278	response to morphine	Cnr1	IMP		Rat	PMID:19804815\|RGD:2314642
Biological Process	GO:0035094	response to nicotine	Cnr1	IMP		Rat	PMID:19463710\|RGD:2314667
Biological Process	GO:0007584	response to nutrient	Cnr1	IEP		Rat	PMID:19807847\|RGD:2314641
Biological Process	GO:0098921	retrograde trans-synaptic signaling by endocannabinoid	Cnr1	IDA		Mouse	PMID:11516401
Biological Process	GO:0098921	retrograde trans-synaptic signaling by endocannabinoid	Cnr1	IMP		Mouse	PMID:11516401
Biological Process	GO:0019233	sensory perception of pain	Cnr1	IMP		Rat	PMID:20035773\|RGD:2316190
Biological Process	GO:0007283	spermatogenesis	Cnr1	IEP		Rat	PMID:18614700\|RGD:2316218
Biological Process	GO:0099553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	Cnr1	IMP		Mouse	MGI:MGI:5819353\|PMID:16540577

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.