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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cnr1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnr1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0004949cannabinoid receptor activityCNR1IDAHumanPMID:18761332
Molecular FunctionGO:0004949cannabinoid receptor activityCnr1IMPMousePMID:27826249
Molecular FunctionGO:0004949cannabinoid receptor activityCnr1IMPMousePMID:27828947
Molecular FunctionGO:0004949cannabinoid receptor activityCnr1IMPRatPMID:2165569|RGD:1298770
Molecular FunctionGO:0042802identical protein bindingCNR1IPIUniProtKB:P21554HumanPMID:20590567
Molecular FunctionGO:0042802identical protein bindingCNR1IPIUniProtKB:P21554HumanPMID:28734930
Molecular FunctionGO:0005515protein bindingCNR1IPIUniProtKB:P29274HumanPMID:17356572
Molecular FunctionGO:0005515protein bindingCNR1IPIUniProtKB:Q96F85HumanPMID:17895407
Molecular FunctionGO:0005515protein bindingCNR1IPIUniProtKB:P29274HumanPMID:23296780
Molecular FunctionGO:0005515protein bindingCNR1IPIUniProtKB:P29274HumanPMID:28102227
Molecular FunctionGO:0005515protein bindingCnr1IPIUniProtKB:P30543RatPMID:17356572|RGD:8554571
Molecular FunctionGO:0005515protein bindingCnr1IPIUniProtKB:Q5M7A7RatPMID:17895407|RGD:13461761
Cellular ComponentGO:0015629actin cytoskeletonCNR1IDAHumanGO_REF:0000052
Cellular ComponentGO:0030424axonCnr1IDAMousePMID:20962221
Cellular ComponentGO:0098982GABA-ergic synapseCnr1IDAMousePMID:11516401
Cellular ComponentGO:0098982GABA-ergic synapseCnr1IMPMousePMID:11516401
Cellular ComponentGO:0098982GABA-ergic synapseCnr1IDAMousePMID:27828947
Cellular ComponentGO:0098982GABA-ergic synapseCnr1IMPMousePMID:27828947
Cellular ComponentGO:0098978glutamatergic synapseCnr1IMPMousePMID:11516401
Cellular ComponentGO:0098978glutamatergic synapseCnr1IDAMousePMID:11516401
Cellular ComponentGO:0098978glutamatergic synapseCnr1IMPMousePMID:27828947
Cellular ComponentGO:0098978glutamatergic synapseCnr1IDAMousePMID:27828947
Cellular ComponentGO:0030426growth coneCnr1IDAMousePMID:20962221
Cellular ComponentGO:0043231intracellular membrane-bounded organelleCnr1IDARatPMID:19906012|RGD:2314635
Cellular ComponentGO:0045121membrane raftCnr1IDARatPMID:21895628|RGD:10047252
Cellular ComponentGO:0005739mitochondrionCnr1IDAMousePMID:27826249
Cellular ComponentGO:0005739mitochondrionCnr1IDAMousePMID:27828947
Cellular ComponentGO:0005886plasma membraneCNR1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneCNR1IDAHumanPMID:17895407
Cellular ComponentGO:0005886plasma membraneCnr1IDARatPMID:17895407|RGD:13461761
Cellular ComponentGO:0042734presynaptic membraneCnr1IDAMouseMGI:MGI:5819353|PMID:16540577
Cellular ComponentGO:0042734presynaptic membraneCnr1IDAMousePMID:27828947
Cellular ComponentGO:0042734presynaptic membraneCnr1IMPMousePMID:27828947
Biological ProcessGO:0007188adenylate cyclase-modulating G protein-coupled receptor signaling pathwayCNR1IDAHumanPMID:18761332
Biological ProcessGO:0007568agingCnr1IMPRatPMID:19679649|RGD:2314647
Biological ProcessGO:0007413axonal fasciculationCnr1IMPMGI:MGI:1857736MousePMID:20962221
Biological ProcessGO:0007413axonal fasciculationcnr1IMPZFIN:ZDB-MRPHLNO-080805-1ZfishPMID:18378465
Biological ProcessGO:0007413axonal fasciculationcnr1IMPZFIN:ZDB-MRPHLNO-080805-2ZfishPMID:18378465
Biological ProcessGO:0007409axonogenesiscnr1IMPZFIN:ZDB-MRPHLNO-080805-1ZfishPMID:18378465
Biological ProcessGO:0007409axonogenesiscnr1IMPZFIN:ZDB-MRPHLNO-080805-2ZfishPMID:18378465
Biological ProcessGO:0038171cannabinoid signaling pathwayCNR1IDAHumanPMID:17895407
Biological ProcessGO:0038171cannabinoid signaling pathwayCnr1IMPMouseMGI:MGI:5819353|PMID:16540577
Biological ProcessGO:0038171cannabinoid signaling pathwayCnr1IDARatPMID:17895407|RGD:13461761
Biological ProcessGO:0007186G protein-coupled receptor signaling pathwayCnr1IMPRatPMID:2165569|RGD:1298770
Biological ProcessGO:0042593glucose homeostasisCnr1IPIMGI:MGI:2684950MousePMID:23954414
Biological ProcessGO:0007611learning or memoryCnr1IMPRatPMID:19880592|RGD:2314636
Biological ProcessGO:0008610lipid biosynthetic processcnr1IMPZFIN:ZDB-GENO-130930-7ZfishPMID:23315130
Biological ProcessGO:0001889liver developmentcnr1IGIZFIN:ZDB-GENE-090812-3ZfishPMID:26884397
Biological ProcessGO:0001889liver developmentcnr1IMPZFIN:ZDB-GENO-170314-1ZfishPMID:26884397
Biological ProcessGO:0001889liver developmentcnr1IGIZFIN:ZDB-GENE-070410-8ZfishPMID:26884397
Biological ProcessGO:0060135maternal process involved in female pregnancyCnr1IEPRatPMID:19860893|RGD:2316191
Biological ProcessGO:0007613memoryCnr1IDARatPMID:19666083|RGD:2314648
Biological ProcessGO:0006555methionine metabolic processcnr1IMPZFIN:ZDB-GENO-170314-1ZfishPMID:26884397
Biological ProcessGO:0045759negative regulation of action potentialCnr1IMPRatPMID:20067581|RGD:2316187
Biological ProcessGO:0045776negative regulation of blood pressureCnr1IMPRatPMID:19295473|RGD:2314676
Biological ProcessGO:0033602negative regulation of dopamine secretionCnr1IMPRatPMID:19187091|RGD:2314679
Biological ProcessGO:0031999negative regulation of fatty acid beta-oxidationCnr1IMPRatPMID:19724020|RGD:2314644
Biological ProcessGO:0033004negative regulation of mast cell activationCnr1IDARatPMID:18552882|RGD:2316220
Biological ProcessGO:0043271negative regulation of monoatomic ion transportCnr1IDARatPMID:19463903|RGD:2314666
Biological ProcessGO:0051001negative regulation of nitric-oxide synthase activityCnr1IMPRatPMID:18561998|RGD:2316219
Biological ProcessGO:0014063negative regulation of serotonin secretionCnr1IMPRatPMID:30217553|RGD:15023474
Biological ProcessGO:0002866positive regulation of acute inflammatory response to antigenic stimulusCnr1IMPRatPMID:19282305|RGD:2314677
Biological ProcessGO:0043065positive regulation of apoptotic processCnr1IMPRatPMID:19560819|RGD:2314660
Biological ProcessGO:0045777positive regulation of blood pressureCnr1IMPRatPMID:19553924|RGD:2314662
Biological ProcessGO:2000253positive regulation of feeding behaviorcnr1IMPZFIN:ZDB-MRPHLNO-130312-11ZfishPMID:23300705
Biological ProcessGO:0031622positive regulation of fever generationCnr1IMPRatPMID:19681872|RGD:2314645
Biological ProcessGO:0010976positive regulation of neuron projection developmentCnr1IDARatPMID:19861414|RGD:2314637
Biological ProcessGO:0060259regulation of feeding behaviorCnr1IMPRatPMID:19575185|RGD:2314659
Biological ProcessGO:0050796regulation of insulin secretionCnr1IMPRatPMID:19644453|RGD:2314628
Biological ProcessGO:0019216regulation of lipid metabolic processCnr1IMPRatPMID:19325539|RGD:2314630
Biological ProcessGO:0060405regulation of penile erectionCnr1IMPRatPMID:17850365|RGD:2314634
Biological ProcessGO:0099509regulation of presynaptic cytosolic calcium ion concentrationCnr1IMPMousePMID:11516401
Biological ProcessGO:0099509regulation of presynaptic cytosolic calcium ion concentrationCnr1IDAMousePMID:11516401
Biological ProcessGO:0032228regulation of synaptic transmission, GABAergicCnr1IMPRatPMID:19725112|RGD:2314643
Biological ProcessGO:0051966regulation of synaptic transmission, glutamatergicCnr1IMPRatPMID:19725112|RGD:2314643
Biological ProcessGO:0042220response to cocaineCnr1IMPRatPMID:19401177|RGD:2314673
Biological ProcessGO:0045471response to ethanolCnr1IMPRatPMID:19860799|RGD:2314638
Biological ProcessGO:0032496response to lipopolysaccharideCnr1IMPRatPMID:19295473|RGD:2314676
Biological ProcessGO:0032496response to lipopolysaccharideCnr1IMPRatPMID:19681872|RGD:2314645
Biological ProcessGO:0043278response to morphineCnr1IMPRatPMID:19463710|RGD:2314667
Biological ProcessGO:0043278response to morphineCnr1IMPRatPMID:19804815|RGD:2314642
Biological ProcessGO:0035094response to nicotineCnr1IMPRatPMID:19463710|RGD:2314667
Biological ProcessGO:0007584response to nutrientCnr1IEPRatPMID:19807847|RGD:2314641
Biological ProcessGO:0098921retrograde trans-synaptic signaling by endocannabinoidCnr1IDAMousePMID:11516401
Biological ProcessGO:0098921retrograde trans-synaptic signaling by endocannabinoidCnr1IMPMousePMID:11516401
Biological ProcessGO:0019233sensory perception of painCnr1IMPRatPMID:20035773|RGD:2316190
Biological ProcessGO:0007283spermatogenesisCnr1IEPRatPMID:18614700|RGD:2316218
Biological ProcessGO:0099553trans-synaptic signaling by endocannabinoid, modulating synaptic transmissionCnr1IMPMouseMGI:MGI:5819353|PMID:16540577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory