Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNR2
  • Mouse genes Cnr2
  • Rat genes Cnr2
  • Zfish genes cnr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cnr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004949	cannabinoid receptor activity	Cnr2	IDA		Rat	PMID:10688601|RGD:632458
Molecular Function	GO:0004930	G protein-coupled receptor activity	Cnr2	IDA		Rat	PMID:10688601|RGD:632458
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q13501	Human	PMID:31616248
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:I3L0A0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:P13236	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q14802-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q6ICL7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q6ZT21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q8IXM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q8N2M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q8N387	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q969S6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q96AA3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9BSR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9NP94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9NRZ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9NWH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9UKJ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9Y548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CNR2	IPI	UniProtKB:Q9Y6D0	Human	PMID:32296183
Cellular Component	GO:0030425	dendrite	Cnr2	IDA		Rat	PMID:18991891|RGD:2316198
Cellular Component	GO:0005783	endoplasmic reticulum	CNR2	IDA		Human	PMID:28364261
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	Cnr2	IDA		Rat	PMID:18798269|RGD:2316216
Cellular Component	GO:0043005	neuron projection	Cnr2	IDA		Rat	PMID:18829105|RGD:2316215
Cellular Component	GO:0043025	neuronal cell body	Cnr2	IDA		Rat	PMID:18991891|RGD:2316198
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Cnr2	IDA		Rat	PMID:12084572|RGD:632455
Biological Process	GO:0060218	hematopoietic stem cell differentiation	cnr2	IMP	ZFIN:ZDB-MRPHLNO-151124-6	Zfish	PMID:25931248
Biological Process	GO:0035701	hematopoietic stem cell migration	cnr2	IDA		Zfish	PMID:25931248
Biological Process	GO:0097241	hematopoietic stem cell migration to bone marrow	cnr2	IDA		Zfish	PMID:25931248
Biological Process	GO:0030097	hemopoiesis	cnr2	IDA		Zfish	PMID:25931248
Biological Process	GO:0030097	hemopoiesis	cnr2	IMP	ZFIN:ZDB-MRPHLNO-151124-6	Zfish	PMID:25931248
Biological Process	GO:0030595	leukocyte chemotaxis	Cnr2	IDA		Mouse	PMID:25348153
Biological Process	GO:0001889	liver development	cnr2	IGI	ZFIN:ZDB-GENE-070410-8	Zfish	PMID:26884397
Biological Process	GO:0001889	liver development	cnr2	IMP	ZFIN:ZDB-GENO-170314-2	Zfish	PMID:26884397
Biological Process	GO:0001889	liver development	cnr2	IGI	ZFIN:ZDB-GENE-090812-3	Zfish	PMID:26884397
Biological Process	GO:0006555	methionine metabolic process	cnr2	IMP	ZFIN:ZDB-GENO-170314-2	Zfish	PMID:26884397
Biological Process	GO:0045759	negative regulation of action potential	Cnr2	IMP		Rat	PMID:19616018|RGD:2316192
Biological Process	GO:0050728	negative regulation of inflammatory response	Cnr2	IDA		Rat	PMID:20067581|RGD:2316187
Biological Process	GO:0033004	negative regulation of mast cell activation	Cnr2	IDA		Rat	PMID:18552882|RGD:2316220
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	Cnr2	IMP		Rat	PMID:18561998|RGD:2316219
Biological Process	GO:0032229	negative regulation of synaptic transmission, GABAergic	Cnr2	IMP		Rat	PMID:19616018|RGD:2316192
Biological Process	GO:0001975	response to amphetamine	Cnr2	IEP		Rat	PMID:20067581|RGD:2316187
Biological Process	GO:0032496	response to lipopolysaccharide	Cnr2	IMP		Rat	PMID:18483180|RGD:2316221
Biological Process	GO:0019233	sensory perception of pain	Cnr2	IMP		Rat	PMID:19409856|RGD:2316193

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern