About   Help   FAQ
Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cntfr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cntfr
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0004897ciliary neurotrophic factor receptor activityCNTFRIDAHumanPMID:12643274
Molecular FunctionGO:0004897ciliary neurotrophic factor receptor activityCntfrIGIMGI:MGI:88439MousePMID:7585948
Molecular FunctionGO:0004897ciliary neurotrophic factor receptor activityCntfrIMPRatPMID:8381290|RGD:1304013
Molecular FunctionGO:0019955cytokine bindingCNTFRIPIUniProtKB:Q9UBD9HumanPMID:15272019
Molecular FunctionGO:0019955cytokine bindingCntfrIPIRGD:2370RatPMID:1648265|RGD:1626161
Molecular FunctionGO:0005515protein bindingCNTFRIPIUniProtKB:P26441HumanPMID:18775332
Molecular FunctionGO:0005515protein bindingCNTFRIPIUniProtKB:Q8IVG9HumanPMID:19386761
Molecular FunctionGO:0005515protein bindingCNTFRIPIUniProtKB:P26441HumanPMID:20584990
Molecular FunctionGO:0005515protein bindingCNTFRIPIUniProtKB:Q92673HumanPMID:26858303
Molecular FunctionGO:0005515protein bindingCNTFRIPIUniProtKB:Q9UBD9:PRO_0000015616HumanPMID:26858303
Molecular FunctionGO:0005515protein bindingCntfrIPIPR:P83714MousePMID:15051883
Molecular FunctionGO:0005102signaling receptor bindingCNTFRIPIUniProtKB:P40189HumanPMID:12707266
Molecular FunctionGO:0005102signaling receptor bindingCNTFRIPIUniProtKB:P42702HumanPMID:12707266
Cellular ComponentGO:0016324apical plasma membraneCNTFRIDAHumanPMID:21912637
Cellular ComponentGO:0070110ciliary neurotrophic factor receptor complexCNTFRIDAHumanPMID:12643274
Cellular ComponentGO:0097059CNTFR-CLCF1 complexCNTFRIDAHumanPMID:11285233
Biological ProcessGO:0003360brainstem developmentCntfrIMPMGI:MGI:2181046MousePMID:7585948
Biological ProcessGO:0070120ciliary neurotrophic factor-mediated signaling pathwayCNTFRIDAHumanPMID:12643274
Biological ProcessGO:0070120ciliary neurotrophic factor-mediated signaling pathwayCntfrIGIMGI:MGI:88439MousePMID:7585948
Biological ProcessGO:0097049motor neuron apoptotic processCntfrIMPMGI:MGI:2181046MousePMID:11312299
Biological ProcessGO:0097049motor neuron apoptotic processCntfrIMPMGI:MGI:3528869MousePMID:18588528
Biological ProcessGO:2000672negative regulation of motor neuron apoptotic processCntfrIMPMGI:MGI:3528869MousePMID:18588528
Biological ProcessGO:2000672negative regulation of motor neuron apoptotic processCntfrIMPMGI:MGI:2181046MousePMID:11312299
Biological ProcessGO:0043524negative regulation of neuron apoptotic processCNTFRIMPHumanPMID:19386761
Biological ProcessGO:0048680positive regulation of axon regenerationcntfrIMPZFIN:ZDB-MRPHLNO-140620-5ZfishPMID:24523552
Biological ProcessGO:0008284positive regulation of cell population proliferationCntfrIGIMGI:MGI:2684607MousePMID:15051883
Biological ProcessGO:0007548sex differentiationCntfrIMPMGI:MGI:2181046MousePMID:10526311
Biological ProcessGO:0060538skeletal muscle organ developmentCntfrIMPMGI:MGI:2181046MousePMID:10526311
Biological ProcessGO:0001967suckling behaviorCntfrIMPMGI:MGI:2181046MousePMID:7585948

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory