Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNTN2
  • Mouse genes Cntn2
  • Rat genes Cntn2
  • Zfish genes cntn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cntn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	Cntn2	IDA		Mouse	PMID:19458237
Molecular Function	GO:0005515	protein binding	CNTN2	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cntn2	IPI	UniProtKB:Q9CPW0	Mouse	PMID:25707359
Molecular Function	GO:0005515	protein binding	Cntn2	IPI	PR:Q9CPW0	Mouse	PMID:20962216
Molecular Function	GO:0005515	protein binding	Cntn2	IPI	PR:P63141	Mouse	PMID:20962216
Molecular Function	GO:0005515	protein binding	Cntn2	IPI	PR:P11627	Mouse	PMID:18550718
Molecular Function	GO:0005515	protein binding	Cntn2	IPI	PR:P12023	Mouse	PMID:19029034
Molecular Function	GO:0005515	protein binding	Cntn2	IPI	PR:P24807	Mouse	PMID:19458237
Molecular Function	GO:0043621	protein self-association	Cntn2	IPI	PR:Q61330	Mouse	PMID:18550718
Cellular Component	GO:0030424	axon	Cntn2	IDA		Mouse	PMID:8089271
Cellular Component	GO:0030424	axon	Cntn2	IDA		Mouse	PMID:16701205
Cellular Component	GO:0030424	axon	Cntn2	IDA		Mouse	PMID:15964824
Cellular Component	GO:0030424	axon	Cntn2	IDA		Mouse	PMID:18650339
Cellular Component	GO:0030424	axon	Cntn2	IDA		Mouse	PMID:17086203
Cellular Component	GO:0030424	axon	Cntn2	IDA		Mouse	PMID:12950086
Cellular Component	GO:0043194	axon initial segment	Cntn2	IDA		Mouse	PMID:18509034
Cellular Component	GO:0009986	cell surface	Cntn2	IDA		Mouse	PMID:8089271
Cellular Component	GO:0009986	cell surface	Cntn2	IDA		Mouse	PMID:17086203
Cellular Component	GO:0044224	juxtaparanode region of axon	Cntn2	IDA		Mouse	MGI:MGI:2675531|PMID:12963709
Cellular Component	GO:0043209	myelin sheath	Cntn2	IDA		Mouse	MGI:MGI:2675531|PMID:12963709
Cellular Component	GO:0043005	neuron projection	Cntn2	IDA		Mouse	PMID:18650339
Cellular Component	GO:0043025	neuronal cell body	Cntn2	IDA		Mouse	PMID:8089271
Cellular Component	GO:0033268	node of Ranvier	Cntn2	IDA		Mouse	MGI:MGI:2675531|PMID:12963709
Cellular Component	GO:0005886	plasma membrane	Cntn2	IDA		Rat	PMID:18179895|RGD:8553826
Cellular Component	GO:0045211	postsynaptic membrane	CNTN2	IDA		Human	PMID:26217189
Cellular Component	GO:0045211	postsynaptic membrane	CNTN2	IMP		Human	PMID:26217189
Cellular Component	GO:0045202	synapse	Cntn2	IDA		Rat	PMID:18179895|RGD:8553826
Biological Process	GO:0007628	adult walking behavior	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18760366
Biological Process	GO:0048677	axon extension involved in regeneration	cntn2	IMP	ZFIN:ZDB-MRPHLNO-130215-3	Zfish	PMID:23285014
Biological Process	GO:0007411	axon guidance	Cntn2	IMP	MGI:MGI:2677610	Mouse	PMID:18550718
Biological Process	GO:0007411	axon guidance	Cntn2	IGI	MGI:MGI:107558	Mouse	PMID:18550718
Biological Process	GO:0007411	axon guidance	Cntn2	IGI	MGI:MGI:96721	Mouse	PMID:18550718
Biological Process	GO:0007413	axonal fasciculation	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18650339
Biological Process	GO:0007409	axonogenesis	Cntn2	IDA		Rat	PMID:2317872|RGD:727707
Biological Process	GO:0007409	axonogenesis	cntn2	IMP	ZFIN:ZDB-MRPHLNO-051128-5	Zfish	PMID:18289389
Biological Process	GO:0007160	cell-matrix adhesion	Cntn2	IDA		Rat	PMID:2317872|RGD:727707
Biological Process	GO:0007417	central nervous system development	cntn2	IMP	ZFIN:ZDB-MRPHLNO-051128-5	Zfish	PMID:16280593
Biological Process	GO:0007417	central nervous system development	cntn2	IMP	ZFIN:ZDB-MRPHLNO-051128-6	Zfish	PMID:16280593
Biological Process	GO:0022010	central nervous system myelination	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18650339
Biological Process	GO:0021853	cerebral cortex GABAergic interneuron migration	Cntn2	IMP		Mouse	PMID:11714688
Biological Process	GO:0045163	clustering of voltage-gated potassium channels	Cntn2	IMP		Mouse	MGI:MGI:2675531|PMID:12963709
Biological Process	GO:0051649	establishment of localization in cell	Cntn2	IDA		Mouse	PMID:18550718
Biological Process	GO:0071206	establishment of protein localization to juxtaparanode region of axon	Cntn2	IDA		Mouse	MGI:MGI:2675529|PMID:12975355
Biological Process	GO:0045444	fat cell differentiation	Cntn2	IMP	MGI:MGI:2677610	Mouse	PMID:22752552
Biological Process	GO:0001973	G protein-coupled adenosine receptor signaling pathway	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:11178983
Biological Process	GO:0007612	learning	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18760366
Biological Process	GO:0000226	microtubule cytoskeleton organization	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18650339
Biological Process	GO:0045665	negative regulation of neuron differentiation	Cntn2	IGI	MGI:MGI:88059	Mouse	PMID:18278038
Biological Process	GO:0030182	neuron differentiation	Cntn2	IGI	MGI:MGI:88059	Mouse	PMID:18278038
Biological Process	GO:0001764	neuron migration	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:16225856
Biological Process	GO:0001764	neuron migration	Cntn2	IMP		Mouse	PMID:11807022
Biological Process	GO:0001764	neuron migration	cntn2	IGI	ZFIN:ZDB-MRPHLNO-041217-5,ZFIN:ZDB-MRPHLNO-051128-5	Zfish	PMID:19013446
Biological Process	GO:0001764	neuron migration	cntn2	IGI	ZFIN:ZDB-MRPHLNO-051128-5,ZFIN:ZDB-MRPHLNO-060119-1	Zfish	PMID:19013446
Biological Process	GO:0001764	neuron migration	cntn2	IMP	ZFIN:ZDB-MRPHLNO-051128-5	Zfish	PMID:19013446
Biological Process	GO:0031175	neuron projection development	Cntn2	IGI	MGI:MGI:88323	Mouse	PMID:19458237
Biological Process	GO:0031175	neuron projection development	Cntn2	IGI	MGI:MGI:1914047	Mouse	PMID:19458237
Biological Process	GO:0031175	neuron projection development	Cntn2	IGI	MGI:MGI:105980	Mouse	PMID:19458237
Biological Process	GO:0060168	positive regulation of adenosine receptor signaling pathway	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:11178983
Biological Process	GO:0045773	positive regulation of axon extension	cntn2	IMP	ZFIN:ZDB-MRPHLNO-051128-6	Zfish	PMID:16280593
Biological Process	GO:0045773	positive regulation of axon extension	cntn2	IMP	ZFIN:ZDB-MRPHLNO-051128-5	Zfish	PMID:16280593
Biological Process	GO:0010954	positive regulation of protein processing	Cntn2	IDA		Mouse	PMID:18278038
Biological Process	GO:0097090	presynaptic membrane organization	CNTN2	IMP		Human	PMID:23518707
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Cntn2	IMP		Mouse	MGI:MGI:2675531|PMID:12963709
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Cntn2	IGI	UniProtKB:P22063	Mouse	PMID:20962216
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18760366
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Cntn2	IMP	MGI:MGI:2677610	Mouse	PMID:19109503
Biological Process	GO:0016485	protein processing	Cntn2	IDA		Mouse	PMID:18278038
Biological Process	GO:0031623	receptor internalization	Cntn2	IDA		Mouse	PMID:18550718
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	Cntn2	IMP	MGI:MGI:2677610	Mouse	PMID:22752552
Biological Process	GO:0048710	regulation of astrocyte differentiation	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18650339
Biological Process	GO:0031133	regulation of axon diameter	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18650339
Biological Process	GO:0010769	regulation of cell morphogenesis involved in differentiation	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:18650339
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Cntn2	IMP	MGI:MGI:2181052	Mouse	PMID:11178983
Biological Process	GO:0002021	response to dietary excess	Cntn2	IMP	MGI:MGI:2677610	Mouse	PMID:22752552

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern