Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CNTNAP1
  • Mouse genes Cntnap1
  • Rat genes Cntnap1
  • Zfish genes cntnap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cntnap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CNTNAP1	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	Cntnap1	IPI	UniProtKB:Q9WV92	Mouse	PMID:21632923
Molecular Function	GO:0005515	protein binding	Cntnap1	IPI	UniProtKB:Q63198	Rat	PMID:12963709|RGD:8554274
Molecular Function	GO:0005515	protein binding	Cntnap1	IPI	RGD:1564762	Rat	PMID:9292722|RGD:727622
Molecular Function	GO:0017124	SH3 domain binding	Cntnap1	IDA		Rat	PMID:9118959|RGD:70689
Cellular Component	GO:0030424	axon	Cntnap1	IDA		Rat	PMID:9292722|RGD:727622
Cellular Component	GO:0098978	glutamatergic synapse	Cntnap1	IDA		Mouse	PMID:33148880
Cellular Component	GO:0098978	glutamatergic synapse	Cntnap1	IMP		Mouse	PMID:33148880
Cellular Component	GO:0016020	membrane	Cntnap1	IDA		Rat	PMID:9292722|RGD:727622
Cellular Component	GO:0043209	myelin sheath	Cntnap1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0033270	paranode region of axon	Cntnap1	IDA		Mouse	MGI:MGI:2675529|PMID:12975355
Cellular Component	GO:0033270	paranode region of axon	Cntnap1	IDA		Mouse	MGI:MGI:3621602|PMID:16551741
Cellular Component	GO:0033270	paranode region of axon	Cntnap1	IDA		Mouse	MGI:MGI:5613863|PMID:25378149
Cellular Component	GO:0033270	paranode region of axon	Cntnap1	IDA		Mouse	PMID:20188654
Cellular Component	GO:0033270	paranode region of axon	Cntnap1	IDA		Mouse	PMID:15102918
Cellular Component	GO:0033270	paranode region of axon	Cntnap1	IDA		Rat	PMID:10624965|RGD:8554062
Cellular Component	GO:0048786	presynaptic active zone	Cntnap1	EXP		Rat	PMID:19187093|RGD:10003050
Cellular Component	GO:0048786	presynaptic active zone	Cntnap1	IDA		Rat	PMID:19187093|RGD:10003050
Cellular Component	GO:0005918	septate junction	Cntnap1	IDA		Mouse	PMID:27583434
Biological Process	GO:0007409	axonogenesis	Cntnap1	IMP	MGI:MGI:2384080	Mouse	PMID:28370195
Biological Process	GO:0022010	central nervous system myelination	CNTNAP1	IMP		Human	PMID:28374019
Biological Process	GO:0007010	cytoskeleton organization	Cntnap1	IMP		Mouse	MGI:MGI:3621602|PMID:16551741
Biological Process	GO:0007005	mitochondrion organization	Cntnap1	IMP	MGI:MGI:2384080	Mouse	PMID:28370195
Biological Process	GO:0042552	myelination	Cntnap1	IGI	MGI:MGI:96912	Mouse	PMID:31641127
Biological Process	GO:0042552	myelination	Cntnap1	IGI	MGI:MGI:1914047	Mouse	PMID:31641127
Biological Process	GO:0022011	myelination in peripheral nervous system	CNTNAP1	IMP		Human	PMID:24319099
Biological Process	GO:0022011	myelination in peripheral nervous system	CNTNAP1	IMP		Human	PMID:27818385
Biological Process	GO:0022011	myelination in peripheral nervous system	CNTNAP1	IMP		Human	PMID:28374019
Biological Process	GO:0098529	neuromuscular junction development, skeletal muscle fiber	Cntnap1	IMP	MGI:MGI:2677631	Mouse	PMID:28370195
Biological Process	GO:0098529	neuromuscular junction development, skeletal muscle fiber	Cntnap1	IMP	MGI:MGI:2384080	Mouse	PMID:28370195
Biological Process	GO:0050905	neuromuscular process	Cntnap1	IMP	MGI:MGI:2677631	Mouse	PMID:28370195
Biological Process	GO:0050905	neuromuscular process	Cntnap1	IMP	MGI:MGI:2384080	Mouse	PMID:28370195
Biological Process	GO:0050885	neuromuscular process controlling balance	Cntnap1	IMP		Mouse	MGI:MGI:3621602|PMID:16551741
Biological Process	GO:0050884	neuromuscular process controlling posture	Cntnap1	IMP		Mouse	MGI:MGI:4838147|PMID:19816196
Biological Process	GO:0031175	neuron projection development	Cntnap1	IGI	MGI:MGI:105980	Mouse	PMID:19458237
Biological Process	GO:0048812	neuron projection morphogenesis	CNTNAP1	IMP		Human	PMID:24319099
Biological Process	GO:0048812	neuron projection morphogenesis	CNTNAP1	IMP		Human	PMID:27818385
Biological Process	GO:0048812	neuron projection morphogenesis	Cntnap1	IMP		Mouse	MGI:MGI:3621602|PMID:16551741
Biological Process	GO:0048812	neuron projection morphogenesis	Cntnap1	IMP		Mouse	MGI:MGI:4838147|PMID:19816196
Biological Process	GO:0048812	neuron projection morphogenesis	Cntnap1	IMP		Mouse	MGI:MGI:5613863|PMID:25378149
Biological Process	GO:0019227	neuronal action potential propagation	Cntnap1	IMP		Mouse	MGI:MGI:4838147|PMID:19816196
Biological Process	GO:0030913	paranodal junction assembly	CNTNAP1	IMP		Human	PMID:27818385
Biological Process	GO:0030913	paranodal junction assembly	Cntnap1	IMP		Mouse	MGI:MGI:3621602|PMID:16551741
Biological Process	GO:0030913	paranodal junction assembly	Cntnap1	IMP		Mouse	MGI:MGI:4838147|PMID:19816196
Biological Process	GO:0030913	paranodal junction assembly	Cntnap1	IMP	MGI:MGI:3026869	Mouse	PMID:16687515
Biological Process	GO:1990227	paranodal junction maintenance	Cntnap1	IMP	MGI:MGI:3026869	Mouse	PMID:16687515
Biological Process	GO:0097106	postsynaptic density organization	Cntnap1	IMP	MGI:MGI:2384080	Mouse	PMID:28370195
Biological Process	GO:0071205	protein localization to juxtaparanode region of axon	Cntnap1	IMP		Mouse	MGI:MGI:5613863|PMID:25378149
Biological Process	GO:0002175	protein localization to paranode region of axon	Cntnap1	IMP		Mouse	MGI:MGI:3621602|PMID:16551741
Biological Process	GO:0002175	protein localization to paranode region of axon	Cntnap1	IMP		Mouse	MGI:MGI:4838147|PMID:19816196
Biological Process	GO:0002175	protein localization to paranode region of axon	Cntnap1	IMP	MGI:MGI:3026869	Mouse	PMID:16687515
Biological Process	GO:0090128	regulation of synapse maturation	Cntnap1	IMP		Mouse	PMID:33148880
Biological Process	GO:0090128	regulation of synapse maturation	Cntnap1	IDA		Mouse	PMID:33148880

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern