Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COA8
  • Mouse genes Coa8
  • Rat genes Coa8
  • Zfish genes coa8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Coa8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0099617	matrix side of mitochondrial inner membrane	COA8	IDA		Human	PMID:30552096
Cellular Component	GO:0005739	mitochondrion	COA8	IDA		Human	PMID:25175347
Cellular Component	GO:0005739	mitochondrion	Coa8	IDA		Mouse	MGI:MGI:5294538|PMID:18977203
Cellular Component	GO:0005739	mitochondrion	Coa8	IDA		Mouse	PMID:16782708
Cellular Component	GO:0005739	mitochondrion	Coa8	HDA		Mouse	PMID:18614015
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	Coa8	IDA		Mouse	PMID:16782708
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	COA8	IMP		Human	PMID:25175347
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	COA8	IDA		Human	PMID:30552096
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	Coa8	IDA		Mouse	MGI:MGI:6355662|PMID:30552096
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	COA8	IMP		Human	PMID:25175347
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	COA8	IMP		Human	PMID:25175347
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	COA8	IDA		Human	PMID:30552096
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	Coa8	IDA		Mouse	MGI:MGI:6355662|PMID:30552096
Biological Process	GO:0050821	protein stabilization	COA8	IDA		Human	PMID:30552096
Biological Process	GO:0050821	protein stabilization	Coa8	IDA		Mouse	MGI:MGI:6355662|PMID:30552096
Biological Process	GO:0000302	response to reactive oxygen species	COA8	IDA		Human	PMID:30552096
Biological Process	GO:0000302	response to reactive oxygen species	Coa8	IDA		Mouse	MGI:MGI:6355662|PMID:30552096

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern