Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL18A1
  • Mouse genes Col18a1
  • Rat genes Col18a1
  • Zfish genes col18a1a,col18a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col18a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Col18a1	IPI	UniProtKB:Q9WVJ9	Mouse	MGI:MGI:3709425|PMID:17324935
Cellular Component	GO:0005604	basement membrane	Col18a1	IDA		Mouse	PMID:15254016
Cellular Component	GO:0005604	basement membrane	Col18a1	IDA		Mouse	PMID:7568013
Cellular Component	GO:0005604	basement membrane	Col18a1	IDA		Mouse	PMID:19651211
Cellular Component	GO:0005604	basement membrane	Col18a1	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005604	basement membrane	Col18a1	IDA		Mouse	PMID:12588956
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL18A1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL18A1	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL18A1	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL18A1	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL18A1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL18A1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col18a1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col18a1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	COL18A1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	COL18A1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	COL18A1	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	COL18A1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	COL18A1	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Col18a1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Col18a1	IDA		Rat	PMID:11353854|RGD:1600910
Biological Process	GO:0001525	angiogenesis	Col18a1	IMP	MGI:MGI:2179134	Mouse	PMID:11927538
Biological Process	GO:0001525	angiogenesis	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:0043534	blood vessel endothelial cell migration	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:0072577	endothelial cell apoptotic process	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:0001886	endothelial cell morphogenesis	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:0030198	extracellular matrix organization	Col18a1	IMP	MGI:MGI:2179134	Mouse	PMID:15254016
Biological Process	GO:0001755	neural crest cell migration	col18a1a	IMP	ZFIN:ZDB-MRPHLNO-130327-10,ZFIN:ZDB-MRPHLNO-130327-9	Zfish	PMID:23349938
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	Col18a1	IDA		Mouse	PMID:15188432
Biological Process	GO:0051599	response to hydrostatic pressure	Col18a1	IEP		Rat	PMID:12798059|RGD:1600908
Biological Process	GO:0009410	response to xenobiotic stimulus	Col18a1	IEP		Rat	PMID:11353854|RGD:1600910
Biological Process	GO:0101023	vascular endothelial cell proliferation	Col18a1	IDA		Mouse	PMID:15188432

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern