Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Col1a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes COL1A1
- Mouse genes Col1a1
- Rat genes Col1a1
- Zfish genes col1a1a,col1a1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col1a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	Col1a1	IDA		Mouse	PMID:15383546
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	COL1A1	HDA		Human	PMID:28344315
Molecular Function	GO:0042802	identical protein binding	COL1A1	IDA		Human	PMID:17211858
Molecular Function	GO:0042802	identical protein binding	Col1a1	IPI	PR:P11087	Mouse	PMID:9213002
Molecular Function	GO:0048407	platelet-derived growth factor binding	COL1A1	IDA		Human	PMID:8900172
Molecular Function	GO:0002020	protease binding	COL1A1	IPI	UniProtKB:P39900	Human	PMID:19932771
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:Q15035	Human	PMID:14749390
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:P08123	Human	PMID:18375391
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:O01949	Human	PMID:20015075
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:P02751	Human	PMID:20541508
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:P02751	Human	PMID:25290767
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:P02751	Human	PMID:26848503
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:P08123	Human	PMID:26848503
Molecular Function	GO:0005515	protein binding	COL1A1	IPI	UniProtKB:Q14145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	PR:P21274	Mouse	PMID:17018525
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	PR:P04202	Mouse	PMID:17018525
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	PR:P11087	Mouse	PMID:7629088
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	MGI:MGI:88468	Mouse	PMID:9213002
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	PR:Q01149	Mouse	PMID:7629088
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	RGD:1559436	Rat	PMID:15817460\|RGD:1579812
Molecular Function	GO:0005515	protein binding	Col1a1	IPI	UniProtKB:Q9UBG0	Rat	PMID:26481812\|RGD:13432280
Cellular Component	GO:0005581	collagen trimer	Col1a1	IDA		Mouse	PMID:8686743
Cellular Component	GO:0005581	collagen trimer	Col1a1	IDA		Mouse	PMID:10608859
Cellular Component	GO:0005581	collagen trimer	Col1a1	IDA		Mouse	PMID:7704020
Cellular Component	GO:0005581	collagen trimer	Col1a1	IDA		Mouse	PMID:15383546
Cellular Component	GO:0005581	collagen trimer	Col1a1	IMP	MGI:MGI:2179405	Mouse	PMID:14630726
Cellular Component	GO:0005581	collagen trimer	Col1a1	IDA		Mouse	PMID:17662583
Cellular Component	GO:0005584	collagen type I trimer	COL1A1	IPI		Human	PMID:26848503
Cellular Component	GO:0005584	collagen type I trimer	COL1A1	IPI		Human	PMID:28281531
Cellular Component	GO:0005584	collagen type I trimer	COL1A1	IMP		Human	PMID:14976317
Cellular Component	GO:0005584	collagen type I trimer	COL1A1	IMP		Human	PMID:17576241
Cellular Component	GO:0005584	collagen type I trimer	COL1A1	IDA		Human	PMID:19932771
Cellular Component	GO:0005584	collagen type I trimer	Col1a1	IDA		Mouse	PMID:8018053
Cellular Component	GO:0005584	collagen type I trimer	Col1a1	IMP	MGI:MGI:1857154	Mouse	PMID:7790374
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL1A1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col1a1	HDA		Mouse	MGI:MGI:6201853\|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col1a1	HDA		Mouse	MGI:MGI:6201834\|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col1a1	HDA		Mouse	MGI:MGI:5582867\|PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col1a1	IDA		Mouse	PMID:34368841
Cellular Component	GO:0005737	cytoplasm	Col1a1	IDA		Mouse	PMID:8018053
Cellular Component	GO:0005737	cytoplasm	Col1a1	IDA		Mouse	PMID:29636669
Cellular Component	GO:0005737	cytoplasm	col1a1a	IDA		Zfish	PMID:19757382
Cellular Component	GO:0005783	endoplasmic reticulum	Col1a1	IDA		Rat	PMID:15609627\|RGD:8552887
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:8984825
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:8906420
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:7589890
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:7573384
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:17029294
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:2209468
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:7629088
Cellular Component	GO:0031012	extracellular matrix	Col1a1	IDA		Mouse	PMID:10878613
Cellular Component	GO:0005576	extracellular region	COL1A1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	COL1A1	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	COL1A1	IMP		Human	PMID:20603131
Cellular Component	GO:0005615	extracellular space	Col1a1	HDA		Mouse	MGI:MGI:5640941\|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Col1a1	IDA		Mouse	PMID:34368841
Cellular Component	GO:0005615	extracellular space	Col1a1	IDA		Rat	PMID:2659889\|RGD:2316226
Cellular Component	GO:0005794	Golgi apparatus	Col1a1	IDA		Rat	PMID:15609627\|RGD:8552887
Cellular Component	GO:0030141	secretory granule	Col1a1	IDA		Rat	PMID:15609627\|RGD:8552887
Biological Process	GO:0001568	blood vessel development	COL1A1	IMP		Human	PMID:17211858
Biological Process	GO:0001568	blood vessel development	Col1a1	IMP	MGI:MGI:2179405	Mouse	PMID:14630726
Biological Process	GO:0030282	bone mineralization	col1a1a	IMP	ZFIN:ZDB-GENO-221115-1	Zfish	PMID:35282456
Biological Process	GO:0035630	bone mineralization involved in bone maturation	col1a1a	IMP		Zfish	PMID:29665086
Biological Process	GO:0046849	bone remodeling	col1a1a	IMP	ZFIN:ZDB-GENO-221115-1	Zfish	PMID:35282456
Biological Process	GO:0046849	bone remodeling	col1a1a	IMP		Zfish	PMID:29665086
Biological Process	GO:0060346	bone trabecula formation	Col1a1	IGI	MGI:MGI:97009	Mouse	PMID:17440987
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	Col1a1	IMP	MGI:MGI:3769585	Mouse	PMID:18248096
Biological Process	GO:0071230	cellular response to amino acid stimulus	Col1a1	IDA		Mouse	PMID:20548288
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Col1a1	IEP		Rat	PMID:2016852\|RGD:2316227
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Col1a1	IEP		Rat	PMID:16972247\|RGD:8552747
Biological Process	GO:1902618	cellular response to fluoride	Col1a1	IEP		Rat	PMID:21093551\|RGD:8552690
Biological Process	GO:0071260	cellular response to mechanical stimulus	Col1a1	IEP		Mouse	MGI:MGI:5294512\|PMID:21625049
Biological Process	GO:0071260	cellular response to mechanical stimulus	Col1a1	IEP		Rat	PMID:22615126\|RGD:8552682
Biological Process	GO:0071300	cellular response to retinoic acid	Col1a1	IEP		Rat	PMID:1921334\|RGD:2316228
Biological Process	GO:0071300	cellular response to retinoic acid	Col1a1	IEP		Rat	PMID:21181362\|RGD:8552777
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Col1a1	IEP		Rat	PMID:19362560\|RGD:8554531
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Col1a1	IEP		Rat	PMID:23560091\|RGD:8552683
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Col1a1	IEP		Rat	PMID:17485223\|RGD:8552773
Biological Process	GO:0071306	cellular response to vitamin E	Col1a1	IEP		Rat	PMID:23722449\|RGD:8552711
Biological Process	GO:0032964	collagen biosynthetic process	COL1A1	IMP		Human	PMID:15095409
Biological Process	GO:0030199	collagen fibril organization	COL1A1	IMP		Human	PMID:14976317
Biological Process	GO:0030199	collagen fibril organization	COL1A1	IMP		Human	PMID:15095409
Biological Process	GO:0030199	collagen fibril organization	COL1A1	IMP		Human	PMID:17211858
Biological Process	GO:0030199	collagen fibril organization	COL1A1	IMP		Human	PMID:18375391
Biological Process	GO:0030199	collagen fibril organization	col1a1a	IMP	ZFIN:ZDB-GENO-221115-1	Zfish	PMID:35282456
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col1a1	IDA		Rat	PMID:10970885\|RGD:11079513
Biological Process	GO:0048706	embryonic skeletal system development	COL1A1	IMP		Human	PMID:18553566
Biological Process	GO:0001958	endochondral ossification	Col1a1	IMP	MGI:MGI:1856671	Mouse	PMID:8130375
Biological Process	GO:0060325	face morphogenesis	Col1a1	IGI	MGI:MGI:97009	Mouse	PMID:17440987
Biological Process	GO:0033333	fin development	col1a1a	IMP	ZFIN:ZDB-GENO-111013-8	Zfish	PMID:9007245
Biological Process	GO:0033334	fin morphogenesis	col1a1a	IMP	ZFIN:ZDB-GENO-110630-21	Zfish	PMID:21420398
Biological Process	GO:0031101	fin regeneration	col1a1a	IMP	ZFIN:ZDB-GENO-110630-21	Zfish	PMID:21420398
Biological Process	GO:0001957	intramembranous ossification	Col1a1	IGI	MGI:MGI:97009	Mouse	PMID:17440987
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	Col1a1	IDA		Mouse	PMID:17018525
Biological Process	GO:0001503	ossification	Col1a1	IEP		Rat	PMID:14595530\|RGD:1600917
Biological Process	GO:0001649	osteoblast differentiation	Col1a1	IEP		Mouse	MGI:MGI:3828402\|PMID:16311053
Biological Process	GO:0033339	pectoral fin development	col1a1a	IMP	ZFIN:ZDB-MRPHLNO-110630-1	Zfish	PMID:21420398
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	COL1A1	IDA		Human	PMID:20018240
Biological Process	GO:0030335	positive regulation of cell migration	COL1A1	IDA		Human	PMID:20018240
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	COL1A1	IDA		Human	PMID:20018240
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	COL1A1	IDA		Human	PMID:20018240
Biological Process	GO:0034504	protein localization to nucleus	COL1A1	IDA		Human	PMID:20018240
Biological Process	GO:0015031	protein transport	Col1a1	IMP	MGI:MGI:1856671	Mouse	PMID:8906420
Biological Process	GO:0030278	regulation of ossification	col1a1a	IMP	ZFIN:ZDB-GENO-011017-1	Zfish	PMID:14623232
Biological Process	GO:0051591	response to cAMP	Col1a1	IEP		Rat	PMID:10679825\|RGD:1600920
Biological Process	GO:0031960	response to corticosteroid	Col1a1	IEP		Rat	PMID:14993121\|RGD:1598718
Biological Process	GO:0032355	response to estradiol	Col1a1	IEP		Rat	PMID:2456904\|RGD:727681
Biological Process	GO:1902617	response to fluoride	Col1a1	IEP		Rat	PMID:15552839\|RGD:1600913
Biological Process	GO:0042542	response to hydrogen peroxide	Col1a1	IEP		Rat	PMID:10051504\|RGD:1600921
Biological Process	GO:0055093	response to hyperoxia	Col1a1	IEP		Rat	PMID:11918316\|RGD:8552772
Biological Process	GO:0032868	response to insulin	Col1a1	IEP		Rat	PMID:20818503\|RGD:151667419
Biological Process	GO:0009612	response to mechanical stimulus	Col1a1	IEP		Rat	PMID:11748224\|RGD:1600918
Biological Process	GO:0009612	response to mechanical stimulus	Col1a1	IEP		Rat	PMID:18988763\|RGD:2316225
Biological Process	GO:0007584	response to nutrient	Col1a1	IEP		Rat	PMID:15042712\|RGD:1600915
Biological Process	GO:0031667	response to nutrient levels	Col1a1	IEP		Rat	PMID:20397200\|RGD:8552688
Biological Process	GO:0014070	response to organic cyclic compound	Col1a1	IEP		Rat	PMID:20818503\|RGD:151667419
Biological Process	GO:0043434	response to peptide hormone	Col1a1	IEP		Rat	PMID:10679825\|RGD:1600920
Biological Process	GO:0048545	response to steroid hormone	Col1a1	IEP		Rat	PMID:21842416\|RGD:8552703
Biological Process	GO:0009410	response to xenobiotic stimulus	Col1a1	IEP		Rat	PMID:23069578\|RGD:8552702
Biological Process	GO:0007605	sensory perception of sound	COL1A1	IMP		Human	PMID:17489845
Biological Process	GO:0001501	skeletal system development	COL1A1	IMP		Human	PMID:8097422
Biological Process	GO:0001501	skeletal system development	COL1A1	IMP		Human	PMID:14976317
Biological Process	GO:0001501	skeletal system development	COL1A1	IMP		Human	PMID:1874719
Biological Process	GO:0001501	skeletal system development	Col1a1	IMP		Mouse	PMID:8163675
Biological Process	GO:0001501	skeletal system development	col1a1b	IMP	ZFIN:ZDB-GENO-180503-7	Zfish	PMID:28835471
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-180503-7	Zfish	PMID:30082390
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-110630-21	Zfish	PMID:30082390
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-180503-6	Zfish	PMID:28835471
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-180504-3	Zfish	PMID:28835471
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-180503-8	Zfish	PMID:30082390
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-190402-1	Zfish	PMID:30082390
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-180503-6	Zfish	PMID:30082390
Biological Process	GO:0001501	skeletal system development	col1a1a	IMP	ZFIN:ZDB-GENO-180504-3	Zfish	PMID:30082390
Biological Process	GO:0048705	skeletal system morphogenesis	Col1a1	IGI	MGI:MGI:97009	Mouse	PMID:17440987
Biological Process	GO:0043588	skin development	Col1a1	IMP	MGI:MGI:3769585	Mouse	PMID:18248096
Biological Process	GO:0043589	skin morphogenesis	COL1A1	IMP		Human	PMID:17211858
Biological Process	GO:0044691	tooth eruption	Col1a1	IEP		Rat	PMID:12351664\|RGD:8552770
Biological Process	GO:0034505	tooth mineralization	COL1A1	IMP		Human	PMID:17118335
Biological Process	GO:0007601	visual perception	COL1A1	IMP		Human	PMID:17557158
Biological Process	GO:0042060	wound healing	Col1a1	IMP		Rat	PMID:20647009\|RGD:5688342

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.