Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL4A2
  • Mouse genes Col4a2
  • Rat genes Col4a2
  • Zfish genes col4a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col4a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	COL4A2	HDA		Human	PMID:28344315
Molecular Function	GO:0005515	protein binding	COL4A2	IPI	UniProtKB:P02462	Human	PMID:12011424
Cellular Component	GO:0005604	basement membrane	Col4a2	IDA		Mouse	MGI:MGI:3776221|PMID:16041630
Cellular Component	GO:0005604	basement membrane	Col4a2	IDA		Mouse	PMID:11732842
Cellular Component	GO:0005604	basement membrane	Col4a2	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005587	collagen type IV trimer	Col4a2	IDA		Mouse	PMID:12101409
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a2	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0070062	extracellular exosome	COL4A2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Col4a2	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0007568	aging	Col4a2	IEP		Rat	PMID:28803135|RGD:13450935
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Col4a2	IEP		Mouse	MGI:MGI:5284779|PMID:17525254
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a2	IGI	MGI:MGI:88456	Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a2	IGI	MGI:MGI:2152695	Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a2	IGI	MGI:MGI:104688	Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a2	IGI	MGI:MGI:88467	Mouse	PMID:10970885
Biological Process	GO:0006351	DNA-templated transcription	Col4a2	IDA		Mouse	MGI:MGI:5284779|PMID:17525254
Biological Process	GO:0035987	endodermal cell differentiation	COL4A2	IEP		Human	PMID:23154389
Biological Process	GO:0016525	negative regulation of angiogenesis	COL4A2	IDA		Human	PMID:10625665
Biological Process	GO:0014823	response to activity	Col4a2	IEP		Rat	PMID:28803135|RGD:13450935

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern