Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL5A1
  • Mouse genes Col5a1
  • Rat genes Col5a1
  • Zfish genes col5a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col5a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	Col5a1	IDA		Mouse	PMID:15383546
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	COL5A1	HDA		Human	PMID:28344315
Molecular Function	GO:0008201	heparin binding	COL5A1	IDA		Human	PMID:2203476
Molecular Function	GO:0008201	heparin binding	Col5a1	IDA		Rat	PMID:10852920|RGD:70693
Molecular Function	GO:0048407	platelet-derived growth factor binding	COL5A1	IDA		Human	PMID:8900172
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:P01033	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:P02751-1	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:P08253	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:P13497	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:P24821	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:Q15113	Human	PMID:20979576
Molecular Function	GO:0005515	protein binding	COL5A1	IPI	UniProtKB:P08253	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Col5a1	IPI	PR:Q2QI47	Mouse	PMID:14676276
Molecular Function	GO:0043394	proteoglycan binding	COL5A1	IPI	UniProtKB:Q00657	Human	PMID:9099729
Cellular Component	GO:0005604	basement membrane	Col5a1	IDA		Mouse	PMID:14676276
Cellular Component	GO:0005581	collagen trimer	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:16492673
Cellular Component	GO:0005581	collagen trimer	Col5a1	IDA		Mouse	PMID:17683922
Cellular Component	GO:0005581	collagen trimer	Col5a1	IDA		Mouse	PMID:15383546
Cellular Component	GO:0005588	collagen type V trimer	COL5A1	IMP		Human	PMID:9683580
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	IMP		Human	PMID:14970208
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col5a1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col5a1	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col5a1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0031012	extracellular matrix	Col5a1	IDA		Mouse	PMID:17029294
Cellular Component	GO:0005576	extracellular region	COL5A1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	Col5a1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0001568	blood vessel development	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:16492673
Biological Process	GO:0007155	cell adhesion	COL5A1	IMP		Human	PMID:18305566
Biological Process	GO:0016477	cell migration	COL5A1	IMP		Human	PMID:18305566
Biological Process	GO:0032964	collagen biosynthetic process	COL5A1	IMP		Human	PMID:11278977
Biological Process	GO:0032964	collagen biosynthetic process	COL5A1	IMP		Human	PMID:15095409
Biological Process	GO:0030199	collagen fibril organization	COL5A1	IMP		Human	PMID:11278977
Biological Process	GO:0030199	collagen fibril organization	COL5A1	IMP		Human	PMID:15095409
Biological Process	GO:0030199	collagen fibril organization	COL5A1	IMP		Human	PMID:9683580
Biological Process	GO:0030199	collagen fibril organization	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:16492673
Biological Process	GO:0030199	collagen fibril organization	Col5a1	IGI	MGI:MGI:88446	Mouse	PMID:17029294
Biological Process	GO:0030199	collagen fibril organization	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:17029294
Biological Process	GO:0030199	collagen fibril organization	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:15383546
Biological Process	GO:0030199	collagen fibril organization	Col5a1	IGI	MGI:MGI:88446	Mouse	PMID:21467034
Biological Process	GO:0048592	eye morphogenesis	COL5A1	IMP		Human	PMID:16431952
Biological Process	GO:0003007	heart morphogenesis	Col5a1	IGI	MGI:MGI:88446	Mouse	PMID:17029294
Biological Process	GO:0045112	integrin biosynthetic process	COL5A1	IMP		Human	PMID:18305566
Biological Process	GO:1903225	negative regulation of endodermal cell differentiation	COL5A1	IDA		Human	PMID:23154389
Biological Process	GO:0051128	regulation of cellular component organization	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:15383546
Biological Process	GO:0043588	skin development	COL5A1	IMP		Human	PMID:9683580
Biological Process	GO:0043588	skin development	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:15383546
Biological Process	GO:0043588	skin development	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:16492673
Biological Process	GO:0097435	supramolecular fiber organization	COL5A1	IMP		Human	PMID:14970208
Biological Process	GO:0035989	tendon development	Col5a1	IMP	MGI:MGI:3664598	Mouse	PMID:21467034
Biological Process	GO:0035989	tendon development	Col5a1	IGI	MGI:MGI:88446	Mouse	PMID:21467034
Biological Process	GO:0035313	wound healing, spreading of epidermal cells	COL5A1	IMP		Human	PMID:18305566

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern