Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL6A1
  • Mouse genes Col6a1
  • Rat genes Col6a1
  • Zfish genes col6a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col6a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	COL6A1	IPI	UniProtKB:P12110	Human	PMID:18400749
Molecular Function	GO:0048407	platelet-derived growth factor binding	COL6A1	IDA		Human	PMID:8900172
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL6A1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL6A1	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL6A1	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL6A1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL6A1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL6A1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col6a1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col6a1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col6a1	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0070062	extracellular exosome	COL6A1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	COL6A1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	COL6A1	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Col6a1	IDA		Mouse	PMID:16810681
Cellular Component	GO:0031012	extracellular matrix	Col6a1	IDA		Mouse	PMID:8806434
Cellular Component	GO:0005576	extracellular region	COL6A1	IDA		Human	PMID:18400749
Cellular Component	GO:0005576	extracellular region	COL6A1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	Col6a1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005765	lysosomal membrane	COL6A1	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	COL6A1	HDA		Human	PMID:16210410
Cellular Component	GO:0032991	protein-containing complex	COL6A1	IPI	UniProtKB:P12110	Human	PMID:18400749
Cellular Component	GO:0042383	sarcolemma	Col6a1	IDA		Mouse	PMID:16810681
Biological Process	GO:0071230	cellular response to amino acid stimulus	Col6a1	IDA		Mouse	PMID:20548288
Biological Process	GO:0035987	endodermal cell differentiation	COL6A1	IEP		Human	PMID:23154389
Biological Process	GO:0007626	locomotory behavior	col6a1	IMP	ZFIN:ZDB-MRPHLNO-100623-5	Zfish	PMID:24852368
Biological Process	GO:0061061	muscle structure development	col6a1	IMP	ZFIN:ZDB-MRPHLNO-100623-5	Zfish	PMID:24852368
Biological Process	GO:0001649	osteoblast differentiation	COL6A1	HDA		Human	PMID:16210410
Biological Process	GO:0007519	skeletal muscle tissue development	col6a1	IMP	ZFIN:ZDB-MRPHLNO-100623-5	Zfish	PMID:20338942
Biological Process	GO:0007519	skeletal muscle tissue development	col6a1	IMP	ZFIN:ZDB-MRPHLNO-100623-6	Zfish	PMID:20338942

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern