Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COPS2
  • Mouse genes Cops2
  • Rat genes Cops2
  • Zfish genes cops2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cops2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:O00716	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:P06748	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:P19447	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q13888	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q15643	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q9NPJ6	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q9ULK4	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q9UNS2	Human	PMID:20399188
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:P29991:PRO_0000037946	Human	PMID:21911577
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:P45481	Human	PMID:23441852
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q09472	Human	PMID:23441852
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q92793	Human	PMID:23441852
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q9UNS2	Human	PMID:24421388
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q13098-7	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q9UNS2	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:O00231	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q13098-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:Q9NWS9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	COPS2	IPI	UniProtKB:P49821	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cops2	IPI	UniProtKB:Q9EQ80	Mouse	MGI:MGI:5619492|PMID:12522100
Molecular Function	GO:0005515	protein binding	Cops2	IPI	MGI:MGI:1915363	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops2	IPI	PR:O88545	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops2	IPI	PR:O88544	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops2	IPI	PR:O88543	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops2	IPI	PR:O35864	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops2	IPI	PR:Q99LD4	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops2	IPI	UniProtKB:Q9EQ80	Rat	PMID:12522100|RGD:10047265
Molecular Function	GO:0003714	transcription corepressor activity	Cops2	IDA		Mouse	PMID:15062575
Cellular Component	GO:0008180	COP9 signalosome	COPS2	IPI		Human	PMID:25043011
Cellular Component	GO:0008180	COP9 signalosome	COPS2	IDA		Human	PMID:18850735
Cellular Component	GO:0008180	COP9 signalosome	COPS2	IDA		Human	PMID:9535219
Cellular Component	GO:0008180	COP9 signalosome	Cops2	IDA		Mouse	PMID:9707402
Cellular Component	GO:0005737	cytoplasm	COPS2	IDA		Human	PMID:24421388
Cellular Component	GO:0005737	cytoplasm	COPS2	IDA		Human	PMID:9535219
Cellular Component	GO:0005634	nucleus	COPS2	IDA		Human	PMID:24421388
Cellular Component	GO:0005634	nucleus	Cops2	IDA		Mouse	MGI:MGI:5619492|PMID:12522100
Cellular Component	GO:0005634	nucleus	Cops2	IDA		Mouse	PMID:12606288
Cellular Component	GO:0005634	nucleus	Cops2	IDA		Rat	PMID:12524175|RGD:634483
Biological Process	GO:0001833	inner cell mass cell proliferation	Cops2	IMP	MGI:MGI:2678281	Mouse	PMID:12972599
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cops2	IDA		Mouse	PMID:15062575
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cops2	IDA		Rat	PMID:12522100|RGD:10047265
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cops2	IDA		Rat	PMID:12524175|RGD:634483
Biological Process	GO:0030182	neuron differentiation	Cops2	IDA		Rat	PMID:12524175|RGD:634483
Biological Process	GO:0000338	protein deneddylation	COPS2	IDA		Human	PMID:19141280
Biological Process	GO:0006468	protein phosphorylation	COPS2	IDA		Human	PMID:9535219
Biological Process	GO:0035914	skeletal muscle cell differentiation	Cops2	IMP		Mouse	PMID:22147266
Biological Process	GO:0001834	trophectodermal cell proliferation	Cops2	IMP	MGI:MGI:2678281	Mouse	PMID:12972599

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern